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Hubert Josien
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1

Design-rules for stapled peptides with in vivo activity and..:

Chandramohan, Arun ; Josien, Hubert ; Yuen, Tsz Ying...
Nature Communications.  15 (2024)  1 - p. , 2024
Link: https://doi.org/10.1038/..
 
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2

Leveraging High-Resolution Ion Mobility-Mass Spectrometry f..:

Fawaz, Maria ; Sun, Congliang ; Feng, Yu...
Journal of the American Society for Mass Spectrometry.  , 2024
Link: https://doi.org/10.1021/..
 
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3

A high‐throughput microfluidic mechanoporation platform to ..:

Kasper, Stephen H. ; Otten, Stephanie ; Squadroni, Brian...
Bioengineering & Translational Medicine.  8 (2023)  5 - p. , 2023
Link: https://doi.org/10.1002/..
 
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4

Orally Bioavailable Macrocyclic Peptide That Inhibits Bindi..:

Johns, Douglas G. ; Campeau, Louis-Charles ; Banka, Puja...
Circulation.  148 (2023)  2 - p. 144-158 , 2023
Link: https://doi.org/10.1161/..
 
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5

Design, synthesis and biological evaluation of indane deriv..:

Pio, Barbara ; Chobanian, Harry R. ; Guo, Yan...
Bioorganic & Medicinal Chemistry Letters.  29 (2019)  14 - p. 1842-1848 , 2019
Link: https://doi.org/10.1016/..
 
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6

Bioactivation of GPR40 Agonist MK-8666: Formation of Protei..:

Shang, Jackie ; Tschirret-Guth, Richard ; Cancilla, Mark...
Chemical Research in Toxicology.  33 (2019)  1 - p. 191-201 , 2019
Link: https://doi.org/10.1021/..
 
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7

Design and Synthesis of Novel, Selective GPR40 AgoPAMs:

Plummer, Christopher W. ; Clements, Matthew J. ; Chen, Helen...
ACS Medicinal Chemistry Letters.  8 (2017)  2 - p. 221-226 , 2017
Link: https://doi.org/10.1021/..
 
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8

Iminopyrimidinones: A novel pharmacophore for the developme..:

McKittrick, Brian A. ; Caldwell, John P. ; Bara, Thomas...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  7 - p. 1592-1596 , 2015
Link: https://doi.org/10.1016/..
 
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9

Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a..:

Neelamkavil, Santhosh F. ; Agrawal, Sony ; Bara, Thomas...
ACS Medicinal Chemistry Letters.  7 (2015)  1 - p. 111-116 , 2015
Link: https://doi.org/10.1021/..
 
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10

Structure activity relationship studies of tricyclic bispyr..:

Wu, Wen-Lian ; Asberom, Theodros ; Bara, Thomas...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  3 - p. 844-849 , 2013
Link: https://doi.org/10.1016/..
 
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11

The discovery of fused oxadiazepines as gamma secretase mod..:

Li, Hongmei ; Qin, Jun ; Dhondi, Pawan...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  2 - p. 466-471 , 2013
Link: https://doi.org/10.1016/..
 
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12

Discovery of SCH 900229, a Potent Presenilin 1 Selective γ-..:

Wu, Wen-Lian ; Domalski, Martin ; Burnett, Duane A....
ACS Medicinal Chemistry Letters.  3 (2012)  11 - p. 892-896 , 2012
Link: https://doi.org/10.1021/..
 
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13

Efficient synthesis and reaction pathway studies of novel f..:

Huang, Xianhai ; Pissarnitski, Dmitri ; Li, Hongmei...
Tetrahedron Letters.  53 (2012)  47 - p. 6451-6455 , 2012
Link: https://doi.org/10.1016/..
 
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14

Identification of Presenilin 1-Selective γ-Secretase Inhibi..:

Lee, Julie ; Song, Lixin ; Terracina, Giuseppe...
Biochemistry.  50 (2011)  22 - p. 4973-4980 , 2011
Link: https://doi.org/10.1021/..
 
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15

Cyclic Hydroxyamidines as Amide Isosteres: Discovery of Oxa..:

Sun, Zhong-Yue ; Asberom, Theodros ; Bara, Thomas...
Journal of Medicinal Chemistry.  55 (2011)  1 - p. 489-502 , 2011
Link: https://doi.org/10.1021/..
 
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