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Hurth, Konstanze
26
results:
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Online (26)
Mediatypes
Articles (Online) (18)
OpenAccess-fulltext (8)
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?
1
Ligandability Assessment of IL-1β by Integrated Hit Identif..:
Vulpetti, Anna
;
Rondeau, Jean-Michel
;
Bellance, Marie-Hélène
...
Journal of Medicinal Chemistry. 67 (2024) 10 - p. 8141-8160 , 2024
Link:
https://doi.org/10.1021/..
?
2
Discovery of a selective and biologically active low-molecu..:
Hommel, Ulrich
;
Hurth, Konstanze
;
Rondeau, Jean-Michel
...
Nature Communications. 14 (2023) 1 - p. , 2023
Link:
https://doi.org/10.1038/..
?
3
Discovery of Umibecestat (CNP520): A Potent, Selective, and..:
Machauer, Rainer
;
Lueoend, Rainer
;
Hurth, Konstanze
...
Journal of Medicinal Chemistry. 64 (2021) 20 - p. 15262-15279 , 2021
Link:
https://doi.org/10.1021/..
?
4
Synthesis of the Potent, Selective, and Efficacious β-Secre..:
Rueeger, Heinrich
;
Lueoend, Rainer
;
Machauer, Rainer
...
Journal of Medicinal Chemistry. 64 (2021) 8 - p. 4677-4696 , 2021
Link:
https://doi.org/10.1021/..
?
5
TheBACE‐1 inhibitorCNP520 for prevention trials in Alzheime..:
Neumann, Ulf
;
Ufer, Mike
;
Jacobson, Laura H
...
EMBO Molecular Medicine. 10 (2018) 11 - p. , 2018
Link:
https://doi.org/10.15252..
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6
Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors:
Veenstra, Siem Jakob
;
Rueeger, Heinrich
;
Voegtle, Markus
...
Bioorganic & Medicinal Chemistry Letters. 28 (2018) 12 - p. 2195-2200 , 2018
Link:
https://doi.org/10.1016/..
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7
AQW051, a novel, potent and selective α7 nicotinic ACh rece..:
Feuerbach, Dominik
;
Pezous, Nicole
;
Weiss, Markus
...
British Journal of Pharmacology. 172 (2015) 5 - p. 1292-1304 , 2015
Link:
https://doi.org/10.1111/..
?
8
Regioselective nitration of 3-fluoro-2-substituted benzoic ..:
Hurth, Konstanze
;
Jacquier, Sébastien
;
Lehmann, Hansjörg
.
Tetrahedron Letters. 56 (2015) 22 - p. 2860-2862 , 2015
Link:
https://doi.org/10.1016/..
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9
Exploring subtype selectivity and metabolic stability of a ..:
Hintermann, Samuel
;
Hurth, Konstanze
;
Nozulak, Joachim
...
Bioorganic & Medicinal Chemistry Letters. 21 (2011) 5 - p. 1523-1526 , 2011
Link:
https://doi.org/10.1016/..
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10
Decahydroisoquinoline derivatives as novel non-peptidic, po..:
Troxler, Thomas
;
Hurth, Konstanze
;
Schuh, Karl-Heinrich
...
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 5 - p. 1728-1734 , 2010
Link:
https://doi.org/10.1016/..
?
11
Discovery of novel non-peptidic β-alanine piperazine amide ..:
Troxler, Thomas
;
Hurth, Konstanze
;
Mattes, Henri
...
Bioorganic & Medicinal Chemistry Letters. 19 (2009) 5 - p. 1305-1309 , 2009
Link:
https://doi.org/10.1016/..
?
12
Gamma-lactams—A novel scaffold for highly potent and select..:
Enz, Albert
;
Feuerbach, Dominik
;
Frederiksen, Mathias U.
...
Bioorganic & Medicinal Chemistry Letters. 19 (2009) 5 - p. 1287-1291 , 2009
Link:
https://doi.org/10.1016/..
?
13
Ergoline derivatives as highly potent and selective antagon..:
Troxler, Thomas
;
Enz, Albert
;
Hoyer, Daniel
...
Bioorganic & Medicinal Chemistry Letters. 18 (2008) 3 - p. 979-982 , 2008
Link:
https://doi.org/10.1016/..
?
14
Identification and SAR of potent and selective non-peptide ..:
Troxler, Thomas
;
Hoyer, Daniel
;
Langenegger, Daniel
...
Bioorganic & Medicinal Chemistry Letters. 17 (2007) 14 - p. 3983-3987 , 2007
Link:
https://doi.org/10.1016/..
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15
SAR of the arylpiperazine moiety of obeline somatostatin ss..:
Hurth, Konstanze
;
Enz, Albert
;
Floersheim, Philipp
...
Bioorganic & Medicinal Chemistry Letters. 17 (2007) 14 - p. 3988-3991 , 2007
Link:
https://doi.org/10.1016/..
1-15