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Huszar, Sarah L.
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1

Discovery of MK-8189, a Highly Potent and Selective PDE10A ..:

Layton, Mark E. ; Kern, Jeffrey C. ; Hartingh, Timothy J....
Journal of Medicinal Chemistry.  66 (2023)  2 - p. 1157-1171 , 2023
Link: https://doi.org/10.1021/..
 
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2

Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-..:

Layton, Mark E. ; Reif, Alexander J. ; Hartingh, Timothy J....
Bioorganic & Medicinal Chemistry Letters.  26 (2016)  4 - p. 1260-1264 , 2016
Link: https://doi.org/10.1016/..
 
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3

Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with ..:

Pero, Joseph E. ; Rossi, Michael A. ; Kelly III, Michael J....
ACS Medicinal Chemistry Letters.  7 (2016)  3 - p. 312-317 , 2016
Link: https://doi.org/10.1021/..
 
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4

Discovery of pyrazolopyrimidine phosphodiesterase 10A inhib..:

Raheem, Izzat T. ; Schreier, John D. ; Fuerst, Joy...
Bioorganic & Medicinal Chemistry Letters.  26 (2016)  1 - p. 126-132 , 2016
Link: https://doi.org/10.1016/..
 
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5

Mechanism based neurotoxicity of mGlu5 positive allosteric ..:

Parmentier-Batteur, Sophie ; Hutson, Peter H. ; Menzel, Karsten...
Neuropharmacology.  82 (2014)  - p. 161-173 , 2014
Link: https://doi.org/10.1016/..
 
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6

The novel phosphodiesterase 10A inhibitor THPP-1 has antips..:

Smith, Sean M. ; Uslaner, Jason M. ; Cox, Christopher D....
Neuropharmacology.  64 (2013)  - p. 215-223 , 2013
Link: https://doi.org/10.1016/..
 
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7

Discovery of tetrahydropyridopyrimidine phosphodiesterase 1..:

Raheem, Izzat T. ; Breslin, Michael J. ; Fandozzi, Christine...
Bioorganic & Medicinal Chemistry Letters.  22 (2012)  18 - p. 5903-5908 , 2012
Link: https://doi.org/10.1016/..
 
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8

T-type calcium channel antagonism produces antipsychotic-li..:

Uslaner, Jason M. ; Smith, Sean M. ; Huszar, Sarah L....
Neuropharmacology.  62 (2012)  3 - p. 1413-1421 , 2012
Link: https://doi.org/10.1016/..
 
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9

Discovery of Oxazolobenzimidazoles as Positive Allosteric M..:

Garbaccio, Robert M. ; Brnardic, Edward J. ; Fraley, Mark E....
ACS Medicinal Chemistry Letters.  1 (2010)  8 - p. 406-410 , 2010
Link: https://doi.org/10.1021/..
 
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10

MK-801 produces a deficit in sucrose preference that is rev..:

Vardigan, Joshua D. ; Huszar, Sarah L. ; McNaughton, Caitlyn H...
Pharmacology Biochemistry and Behavior.  95 (2010)  2 - p. 223-229 , 2010
Link: https://doi.org/10.1016/..
 
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11

3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive al..:

Brnardic, Edward J. ; Fraley, Mark E. ; Garbaccio, Robert M....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  10 - p. 3129-3133 , 2010
Link: https://doi.org/10.1016/..
 
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12

Combined administration of an mGlu2/3 receptor agonist and ..:

Uslaner, Jason M. ; Smith, Sean M. ; Huszar, Sarah L....
Psychopharmacology.  206 (2009)  4 - p. 641-651 , 2009
Link: https://doi.org/10.1007/..
 
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13

Discovery of MK-8189, a Highly Potent and Selective PDE10A ..:

Layton, Mark E ; Kern, Jeffrey C ; Hartingh, Timothy J...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884086/.  , 2023
Link: http://www.ncbi.nlm.nih...
 
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14

Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with ..:

Pero, Joseph E ; Rossi, Michael A ; Kelly, Michael J...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789683/.  , 2016
Link: http://www.ncbi.nlm.nih...
 
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15

Discovery of Oxazolobenzimidazoles as Positive Allosteric M..:

Garbaccio, Robert M ; Brnardic, Edward J ; Fraley, Mark E...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC.  , 2010
Link: http://www.ncbi.nlm.nih...
 
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