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Isobe, Yoshiaki
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1

N-(6-phenylpyridazin-3-yl)benzenesulfonamides as highly pot..:

Kimura, Hidenori ; Suda, Hitoshi ; Kassai, Momoe...
Bioorganic & Medicinal Chemistry Letters.  33 (2021)  - p. 127753 , 2021
Link: https://doi.org/10.1016/..
 
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2

Identification of 2-fluoro-8-methyl-11-(1-methyl-1,2,3,6-te..:

Watanabe, Hitoshi ; Ishida, Kyoji ; Yamamoto, Masanori...
Bioorganic & Medicinal Chemistry Letters.  40 (2021)  - p. 127911 , 2021
Link: https://doi.org/10.1016/..
 
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3

Discovery of N-(6-(5-fluoro-2-(piperidin-1-yl)phenyl)pyrida..:

Tsuboi, Katsunori ; Kimura, Hidenori ; Nakatsuji, Yoshie...
Bioorganic & Medicinal Chemistry Letters.  44 (2021)  - p. 128115 , 2021
Link: https://doi.org/10.1016/..
 
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4

Structural analysis reveals TLR7 dynamics underlying antago..:

Tojo, Shingo ; Zhang, Zhikuan ; Matsui, Hiroyuki...
Nature Communications.  11 (2020)  1 - p. , 2020
Link: https://doi.org/10.1038/..
 
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5

Synthesis and pharmacological evaluation of 11-(1,6-dimethy..:

Watanabe, Hitoshi ; Ishida, Kyoji ; Yamamoto, Masanori..
Bioorganic & Medicinal Chemistry Letters.  30 (2020)  21 - p. 127563 , 2020
Link: https://doi.org/10.1016/..
 
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6

Synthesis and biological evaluation of novel orally availab..:

Tobe, Masanori ; Tsuboi, Katsunori ; Hasegawa, Futoshi...
Bioorganic & Medicinal Chemistry Letters.  26 (2016)  4 - p. 1292-1295 , 2016
Link: https://doi.org/10.1016/..
 
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7

Dihydropyrrolo[2,3-d]pyrimidines: Selective Toll-Like Recep..:

Watanabe, Manabu ; Kasai, Mai ; Tomizawa, Hideyuki...
ACS Medicinal Chemistry Letters.  5 (2014)  11 - p. 1235-1239 , 2014
Link: https://doi.org/10.1021/..
 
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8

Crystal Structures and Structure–Activity Relationships of ..:

Tojo, Shingo ; Kohno, Tetsuya ; Tanaka, Tomoyuki...
ACS Medicinal Chemistry Letters.  5 (2014)  10 - p. 1119-1123 , 2014
Link: https://doi.org/10.1021/..
 
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9

Synthesis and evaluation of 8-oxoadenine derivatives as pot..:

Nakamura, Tomoaki ; Wada, Hiroki ; Kurebayashi, Hirotaka...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  3 - p. 669-672 , 2013
Link: https://doi.org/10.1016/..
 
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10

Synthesis of Novel Benzo-Fused Heteroaryl Derivatives as Ca..:

Komiya, Masafumi ; Asano, Shigehiro ; Koike, Nobuyuki...
Chemical and Pharmaceutical Bulletin.  61 (2013)  10 - p. 1094-1097 , 2013
Link: https://doi.org/10.1248/..
 
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11

Synthesis and structure based optimization of 2-(4-phenoxyb..:

Komiya, Masafumi ; Asano, Shigehiro ; Koike, Nobuyuki...
Bioorganic & Medicinal Chemistry.  20 (2012)  23 - p. 6840-6847 , 2012
Link: https://doi.org/10.1016/..
 
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12

Suzuki–Miyaura cross-coupling reaction of aryl and heteroar..:

Asano, Shigehiro ; Kamioka, Seiji ; Isobe, Yoshiaki
Tetrahedron.  68 (2012)  1 - p. 272-279 , 2012
Link: https://doi.org/10.1016/..
 
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13

Structure and activity relationship of 2-(substituted benzo..:

Komiya, Masafumi ; Asano, Shigehiro ; Koike, Nobuyuki...
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  5 - p. 1456-1458 , 2011
Link: https://doi.org/10.1016/..
 
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14

Synthesis and structure–activity relationship of tricyclic ..:

Kubota, Katsumi ; Kurebayashi, Hirotaka ; Miyachi, Hirotaka...
Bioorganic & Medicinal Chemistry.  19 (2011)  9 - p. 3005-3021 , 2011
Link: https://doi.org/10.1016/..
 
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15

Circadian rhythm of enolase in suprachiasmatic nucleus depe..:

Isobe, Yoshiaki ; Hida, Hideki ; Nishino, Hitoo
Journal of Neuroscience Research.  89 (2011)  6 - p. 936-944 , 2011
Link: https://doi.org/10.1002/..
 
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