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Jayaraman, Muthusamy
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1

Investigating the pharmacodynamic durability of GalNAc–siRN..:

Brown, Christopher R ; Gupta, Swati ; Qin, June...
Nucleic Acids Research.  48 (2020)  21 - p. 11827-11844 , 2020
Link: https://doi.org/10.1093/..
 
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2

Chirality Dependent Potency Enhancement and Structural Impa..:

Schlegel, Mark K. ; Foster, Donald J. ; Kel'in, Alexander V....
Journal of the American Chemical Society.  139 (2017)  25 - p. 8537-8546 , 2017
Link: https://doi.org/10.1021/..
 
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3

Structural Basis of Duplex Thermodynamic Stability and Enha..:

Kel′in, Alexander V. ; Zlatev, Ivan ; Harp, Joel...
The Journal of Organic Chemistry.  81 (2016)  6 - p. 2261-2279 , 2016
Link: https://doi.org/10.1021/..
 
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4

Hepatocyte‐Specific Delivery of siRNAs Conjugated to Novel ..:

Rajeev, Kallanthottathil G. ; Nair, Jayaprakash K. ; Jayaraman, Muthusamy...
ChemBioChem.  16 (2015)  6 - p. 903-908 , 2015
Link: https://doi.org/10.1002/..
 
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5

Cover Picture: Hepatocyte‐Specific Delivery of siRNAs Conju..:

Rajeev, Kallanthottathil G. ; Nair, Jayaprakash K. ; Jayaraman, Muthusamy...
ChemBioChem.  16 (2015)  6 - p. 873-873 , 2015
Link: https://doi.org/10.1002/..
 
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6

An immobilized and reusable Cu(i) catalyst for metal ion-fr..:

Eltepu, Laxman ; Jayaraman, Muthusamy ; Rajeev, Kallanthottathil G..
Chem. Commun..  49 (2013)  2 - p. 184-186 , 2013
Link: https://doi.org/10.1039/..
 
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7

Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nano..:

Maier, Martin A ; Jayaraman, Muthusamy ; Matsuda, Shigeo...
Molecular Therapy.  21 (2013)  8 - p. 1570-1578 , 2013
Link: https://doi.org/10.1038/..
 
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8

Lipid Nanoparticles Improve Activity of Single-Stranded siR..:

Prakash, Thazha P. ; Lima, Walt F. ; Murray, Heather M....
ACS Chemical Biology.  8 (2013)  7 - p. 1402-1406 , 2013
Link: https://doi.org/10.1021/..
 
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9

Influence of Polyethylene Glycol Lipid Desorption Rates on ..:

Mui, Barbara L ; Tam, Ying K ; Jayaraman, Muthusamy...
Molecular Therapy - Nucleic Acids.  2 (2013)  - p. e139 , 2013
Link: https://doi.org/10.1038/..
 
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10

Maximizing the Potency of siRNA Lipid Nanoparticles for Hep..:

Jayaraman, Muthusamy ; Ansell, Steven M. ; Mui, Barbara L....
Angewandte Chemie International Edition.  51 (2012)  34 - p. 8529-8533 , 2012
Link: https://doi.org/10.1002/..
 
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11

Maximizing the Potency of siRNA Lipid Nanoparticles for Hep..:

Jayaraman, Muthusamy ; Ansell, Steven M. ; Mui, Barbara L....
Angewandte Chemie.  124 (2012)  34 - p. 8657-8661 , 2012
Link: https://doi.org/10.1002/..
 
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12

Systemic RNAi-mediated Gene Silencing in Nonhuman Primate a..:

Novobrantseva, Tatiana I ; Borodovsky, Anna ; Wong, Jamie...
Molecular Therapy - Nucleic Acids.  1 (2012)  - p. e4 , 2012
Link: https://doi.org/10.1038/..
 
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13

Discovery of (+)-N-(3-Aminopropyl)-N-[1-(5-benzyl-3-methyl-..:

Theoclitou, Maria-Elena ; Aquila, Brian ; Block, Michael H....
Journal of Medicinal Chemistry.  54 (2011)  19 - p. 6734-6750 , 2011
Link: https://doi.org/10.1021/..
 
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14

Targeted Delivery of RNAi Therapeutics With Endogenous and ..:

Akinc, Akin ; Querbes, William ; De, Soma...
Molecular Therapy.  18 (2010)  7 - p. 1357-1364 , 2010
Link: https://doi.org/10.1038/..
 
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15

Rational design of cationic lipids for siRNA delivery:

Semple, Sean C ; Akinc, Akin ; Chen, Jianxin...
Nature Biotechnology.  28 (2010)  2 - p. 172-176 , 2010
Link: https://doi.org/10.1038/..
 
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