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Kaniskan, H. Ümit
94  results:
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1

Application of established computational techniques to iden..:

Nigam, AkshatKumar ; Hurley, Matthew F. D. ; Li, Fengling...
Digital Discovery.  , 2024
Link: https://doi.org/10.1039/..
 
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2

Discovery of the First-in-Class G9a/GLP PROTAC Degrader:

Velez, Julia ; Han, Yulin ; Yim, Hyerin...
Journal of Medicinal Chemistry.  67 (2024)  8 - p. 6397-6409 , 2024
Link: https://doi.org/10.1021/..
 
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3

Structurally Specific Z-DNA Proteolysis Targeting Chimera E..:

Wang, Zhen ; Zhang, Dingpeng ; Qiu, Xing...
Journal of the American Chemical Society.  146 (2024)  11 - p. 7584-7593 , 2024
Link: https://doi.org/10.1021/..
 
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4

Discovery of a novel, highly potent EZH2 PROTAC degrader fo..:

Velez, Julia ; Dale, Brandon ; Park, Kwang-Su...
European Journal of Medicinal Chemistry.  267 (2024)  - p. 116154 , 2024
Link: https://doi.org/10.1016/..
 
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5

Chemically induced degradation of epigenetic targets:

Kabir, Md ; Yu, Xufen ; Kaniskan, H. Ümit.
Chemical Society Reviews.  52 (2023)  13 - p. 4313-4342 , 2023
Link: https://doi.org/10.1039/..
 
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6

Correction: An MDM2 degrader for treatment of acute leukemi..:

Marcellino, Bridget K. ; Yang, Xiaobao ; Ümit Kaniskan, H....
Leukemia.  37 (2023)  8 - p. 1764-1765 , 2023
Link: https://doi.org/10.1038/..
 
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7

Telomere Targeting Chimera Enables Targeted Destruction of ..:

Wang, Zhen ; Liu, Jing ; Chen, He...
Journal of the American Chemical Society.  145 (2023)  19 - p. 10872-10879 , 2023
Link: https://doi.org/10.1021/..
 
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8

Inhibition of USP7 induces p53-independent tumor growth sup..:

Yi, Jingjie ; Li, Huan ; Chu, Bo...
Cell Death & Differentiation.  30 (2023)  7 - p. 1799-1810 , 2023
Link: https://doi.org/10.1038/..
 
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9

Structure-Based Discovery of Inhibitors of the SARS-CoV-2 N..:

Singh, Isha ; Li, Fengling ; Fink, Elissa A....
Journal of Medicinal Chemistry.  66 (2023)  12 - p. 7785-7803 , 2023
Link: https://doi.org/10.1021/..
 
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10

Epigenetic balance ensures mechanistic control of MLL ampli..:

Gray, Zach H. ; Chakraborty, Damayanti ; Duttweiler, Reuben R....
Cell.  186 (2023)  21 - p. 4528-4545.e18 , 2023
Link: https://doi.org/10.1016/..
 
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11

Recent advances in developing degraders & inhibitors of lys..:

Velez, Julia ; Kaniskan, H. Ümit ; Jin, Jian
Current Opinion in Chemical Biology.  76 (2023)  - p. 102356 , 2023
Link: https://doi.org/10.1016/..
 
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12

Generation of host-directed and virus-specific antivirals u..:

Zhao, Nan ; Ho, Jessica Sook Yuin ; Meng, Fanye...
Cell Host & Microbe.  31 (2023)  7 - p. 1154-1169.e10 , 2023
Link: https://doi.org/10.1016/..
 
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13

Methylated Nucleotide-Based Proteolysis-Targeting Chimera E..:

Wang, Zhen ; Liu, Jing ; Qiu, Xing...
Journal of the American Chemical Society.  145 (2023)  40 - p. 21871-21878 , 2023
Link: https://doi.org/10.1021/..
 
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14

Acetylation Targeting Chimera Enables Acetylation of the Tu..:

Kabir, Md ; Sun, Ning ; Hu, Xiaoping...
Journal of the American Chemical Society.  145 (2023)  27 - p. 14932-14944 , 2023
Link: https://doi.org/10.1021/..
 
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15

An MDM2 degrader for treatment of acute leukemias:

Marcellino, Bridget K. ; Yang, Xiaobao ; Ümit Kaniskan, H....
Leukemia.  37 (2022)  2 - p. 370-378 , 2022
Link: https://doi.org/10.1038/..
 
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