E-LIB Suche - Ergebnisse für: Kayser, Frank

1

Prospective discovery of small molecule enhancers of an E3 ..:

Simonetta, Kyle R. ; Taygerly, Joshua ; Boyle, Kathleen...
Nature Communications. 10 (2019) 1 - p. , 2019

Link: https://doi.org/10.1038/..

2

Direct activation of G-protein-gated inward rectifying K+ c..:

Zou, Bende ; Cao, William S ; Guan, Zhiwei...
Sleep. 42 (2018) 3 - p. , 2018

Link: https://doi.org/10.1093/..

3

A Selective Prostaglandin E2 Receptor Subtype 2 (EP2) Antag..:

Fox, Brian M. ; Beck, Hilary P. ; Roveto, Philip M....
Journal of Medicinal Chemistry. 58 (2015) 13 - p. 5256-5273 , 2015

Link: https://doi.org/10.1021/..

4

Discovery and optimization of 5-(2-((1-(phenylsulfonyl)-1,2..:

Wang, Yingcai ; Yu, Ming ; Zhu, Jiang...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 4 - p. 1133-1137 , 2014

Link: https://doi.org/10.1016/..

5

Optimization beyond AMG 232: Discovery and SAR of sulfonami..:

Wang, Yingcai ; Zhu, Jiang ; Liu, Jiwen (Jim)...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 16 - p. 3782-3785 , 2014

Link: https://doi.org/10.1016/..

6

Structure-assisted discovery of the first non-retinoid liga..:

Wang, Yingcai ; Connors, Richard ; Fan, Pingchen...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 13 - p. 2885-2891 , 2014

Link: https://doi.org/10.1016/..

7

Discovery of AMG 232, a Potent, Selective, and Orally Bioav..:

Sun, Daqing ; Li, Zhihong ; Rew, Yosup...
Journal of Medicinal Chemistry. 57 (2014) 4 - p. 1454-1472 , 2014

Link: https://doi.org/10.1021/..

8

Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1..:

Yu, Ming ; (Ken) Zhang, Jian ; Wang, Yingcai...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 1 - p. 156-160 , 2014

Link: https://doi.org/10.1016/..

9

Rational Design and Binding Mode Duality of MDM2–p53 Inhibi..:

Gonzalez-Lopez de Turiso, Felix ; Sun, Daqing ; Rew, Yosup...
Journal of Medicinal Chemistry. 56 (2013) 10 - p. 4053-4070 , 2013

Link: https://doi.org/10.1021/..

10

Structure guided design of a series of sphingosine kinase (..:

Gustin, Darin J. ; Li, Yihong ; Brown, Matthew L....
Bioorganic & Medicinal Chemistry Letters. 23 (2013) 16 - p. 4608-4616 , 2013

Link: https://doi.org/10.1016/..

11

Discovery and optimization of arylsulfonyl 3-(pyridin-2-ylo..:

Zhang, Jian (Ken) ; Li, An-Rong ; Yu, Ming...
Bioorganic & Medicinal Chemistry Letters. 23 (2013) 12 - p. 3609-3613 , 2013

Link: https://doi.org/10.1016/..

12

Discovery of a new binding mode for a series of liver X rec..:

Kopecky, David J. ; Jiao, Xian Yun ; Fisher, Ben...
Bioorganic & Medicinal Chemistry Letters. 22 (2012) 7 - p. 2407-2410 , 2012

Link: https://doi.org/10.1016/..

13

Structure-Based Design of Novel Inhibitors of the MDM2–p53 ..:

Rew, Yosup ; Sun, Daqing ; Gonzalez-Lopez De Turiso, Felix...
Journal of Medicinal Chemistry. 55 (2012) 11 - p. 4936-4954 , 2012

Link: https://doi.org/10.1021/..

14

Synthesis and optimization of substituted furo[2,3-d]-pyrim..:

Jiao, XianYun ; Kopecky, David J. ; Liu, JinSong...
Bioorganic & Medicinal Chemistry Letters. 22 (2012) 19 - p. 6212-6217 , 2012

Link: https://doi.org/10.1016/..

15

Discovery and optimization of a series of liver X receptor ..:

Jiao, XianYun ; Kopecky, David J. ; Fisher, Ben...
Bioorganic & Medicinal Chemistry Letters. 22 (2012) 18 - p. 5966-5970 , 2012

Link: https://doi.org/10.1016/..