E-LIB Suche - Ergebnisse für: Kern, Jeffrey C.

1

Discovery of MK-8189, a Highly Potent and Selective PDE10A ..:

Layton, Mark E. ; Kern, Jeffrey C. ; Hartingh, Timothy J....
Journal of Medicinal Chemistry. 66 (2023) 2 - p. 1157-1171 , 2023

Link: https://doi.org/10.1021/..

2

Structures of active-state orexin receptor 2 rationalize pe..:

Hong, Chuan ; Byrne, Noel J. ; Zamlynny, Beata...
Nature Communications. 12 (2021) 1 - p. , 2021

Link: https://doi.org/10.1038/..

3

Novel Phosphate Modified Cathepsin B Linkers: Improving Aqu..:

Kern, Jeffrey C. ; Dooney, Deborah ; Zhang, Rena...
Bioconjugate Chemistry. 27 (2016) 9 - p. 2081-2088 , 2016

Link: https://doi.org/10.1021/..

4

Discovery of Pyrophosphate Diesters as Tunable, Soluble, an..:

Kern, Jeffrey C. ; Cancilla, Mark ; Dooney, Deborah...
Journal of the American Chemical Society. 138 (2016) 4 - p. 1430-1445 , 2016

Link: https://doi.org/10.1021/..

5

3-(Pyridin-2-yl-ethynyl)benzamide metabotropic glutamate re..:

Gilbert, Adam M. ; Bursavich, Matthew G. ; Lombardi, Sabrina...
Bioorganic & Medicinal Chemistry Letters. 21 (2011) 1 - p. 195-199 , 2011

Link: https://doi.org/10.1016/..

6

Synthesis and evaluation of azabicyclo[3.2.1]octane derivat..:

Crombie, Aimee L. ; Antrilli, Thomas M. ; Campbell, Brandon A....
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 12 - p. 3742-3745 , 2010

Link: https://doi.org/10.1016/..

7

Modulation of Wnt signaling through inhibition of secreted ..:

Moore, William J. ; Kern, Jeffrey C. ; Bhat, Ramesh...
Bioorganic & Medicinal Chemistry. 18 (2010) 1 - p. 190-201 , 2010

Link: https://doi.org/10.1016/..

8

1-Methyl-1H-pyrrole-2-carbonitrile containing tetrahydronap..:

Kern, Jeffrey C. ; Terefenko, Eugene ; Trybulski, Eugene...
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 16 - p. 4816-4818 , 2010

Link: https://doi.org/10.1016/..

9

5-Aryl indanones and derivatives as non-steroidal progester..:

Kern, Jeffrey C. ; Terefenko, Eugene ; Trybulski, Eugene...
Bioorganic & Medicinal Chemistry Letters. 19 (2009) 23 - p. 6666-6669 , 2009

Link: https://doi.org/10.1016/..

10

A small molecule inhibitor of the Wnt antagonist secreted f..:

Bodine, Peter V.N. ; Stauffer, Barbara ; Ponce-de-Leon, Helga...
Bone. 44 (2009) 6 - p. 1063-1068 , 2009

Link: https://doi.org/10.1016/..

11

Modulation of Wnt Signaling Through Inhibition of Secreted ..:

Moore, William J. ; Kern, Jeffrey C. ; Bhat, Ramesh...
Journal of Medicinal Chemistry. 52 (2008) 1 - p. 105-116 , 2008

Link: https://doi.org/10.1021/..

12

Design, Synthesis, and SAR of New Pyrrole-Oxindole Progeste..:

Fensome, Andrew ; Adams, William R. ; Adams, Andrea L....
Journal of Medicinal Chemistry. 51 (2008) 6 - p. 1861-1873 , 2008

Link: https://doi.org/10.1021/..

13

7-Aryl 1,5-dihydro-benzo[e][1,4]oxazepin-2-ones and analogs..:

Zhang, Puwen ; Kern, Jeffrey C. ; Terefenko, Eugene A....
Bioorganic & Medicinal Chemistry. 16 (2008) 13 - p. 6589-6600 , 2008

Link: https://doi.org/10.1016/..

14

1,5-Dihydro-benzo[e][1,4]oxazepin-2(1H)-ones containing a 7..:

Kern, Jeffrey C. ; Terefenko, Eugene A. ; Fensome, Andrew...
Bioorganic & Medicinal Chemistry Letters. 18 (2008) 18 - p. 5015-5017 , 2008

Link: https://doi.org/10.1016/..

15

SAR studies of 6-(arylamino)-4,4-disubstituted-1-methyl-1,4..:

Kern, Jeffrey C. ; Terefenko, Eugene A. ; Fensome, Andrew...
Bioorganic & Medicinal Chemistry Letters. 17 (2007) 1 - p. 189-192 , 2007

Link: https://doi.org/10.1016/..