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Knafels, John D.
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1

In Retrospect: Root-Cause Analysis of Structure–Activity Re..:

Wright, Stephen W. ; Farley, Kathleen A. ; Han, Seungil..
ACS Medicinal Chemistry Letters.  15 (2024)  4 - p. 540-545 , 2024
Link: https://doi.org/10.1021/..
 
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2

Structural studies identify angiotensin II receptor blocker..:

Liu, Shenping ; Kormos, Bethany L. ; Knafels, John D....
Journal of Biological Chemistry.  299 (2023)  3 - p. 102959 , 2023
Link: https://doi.org/10.1016/..
 
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3

Small molecule branched-chain ketoacid dehydrogenase kinase..:

Roth Flach, Rachel J. ; Bollinger, Eliza ; Reyes, Allan R....
Nature Communications.  14 (2023)  1 - p. , 2023
Link: https://doi.org/10.1038/..
 
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4

Macrocyclic Retinoic Acid Receptor-Related Orphan Receptor ..:

Schnute, Mark E. ; Trujillo, John I. ; Lee, Katherine L....
ACS Medicinal Chemistry Letters.  14 (2023)  2 - p. 191-198 , 2023
Link: https://doi.org/10.1021/..
 
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5

Discovery of a Series of Pyrimidine Carboxamides as Inhibit..:

Casimiro-Garcia, Agustin ; Allais, Christophe ; Brennan, Agnes...
Journal of Medicinal Chemistry.  65 (2021)  1 - p. 757-784 , 2021
Link: https://doi.org/10.1021/..
 
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6

Discovery of PF-06835919: A Potent Inhibitor of Ketohexokin..:

Futatsugi, Kentaro ; Smith, Aaron C. ; Tu, Meihua...
Journal of Medicinal Chemistry.  63 (2020)  22 - p. 13546-13560 , 2020
Link: https://doi.org/10.1021/..
 
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7

Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-0682664..:

Gerstenberger, Brian S. ; Ambler, Catherine ; Arnold, Eric P....
Journal of Medicinal Chemistry.  63 (2020)  22 - p. 13561-13577 , 2020
Link: https://doi.org/10.1021/..
 
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8

Demonstration of In Vitro to In Vivo Translation of a TYK2 ..:

Gerstenberger, Brian S. ; Banker, Mary Ellen ; Clark, James D....
Scientific Reports.  10 (2020)  1 - p. , 2020
Link: https://doi.org/10.1038/..
 
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9

An Intracellular Allosteric Modulator Binding Pocket in SK2..:

Cho, Lily T.-Y. ; Alexandrou, Aristos J. ; Torella, Rubben...
Structure.  26 (2018)  4 - p. 533-544.e3 , 2018
Link: https://doi.org/10.1016/..
 
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10

Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoi..:

Fensome, Andrew ; Ambler, Catherine M. ; Arnold, Eric...
Journal of Medicinal Chemistry.  61 (2018)  19 - p. 8597-8612 , 2018
Link: https://doi.org/10.1021/..
 
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11

Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Cov..:

Casimiro-Garcia, Agustin ; Trujillo, John I. ; Vajdos, Felix...
Journal of Medicinal Chemistry.  61 (2018)  23 - p. 10665-10699 , 2018
Link: https://doi.org/10.1021/..
 
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12

Discovery of Fragment-Derived Small Molecules for in Vivo I..:

Huard, Kim ; Ahn, Kay ; Amor, Paul...
Journal of Medicinal Chemistry.  60 (2017)  18 - p. 7835-7849 , 2017
Link: https://doi.org/10.1021/..
 
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13

Azetidine and Piperidine Carbamates as Efficient, Covalent ..:

Butler, Christopher R. ; Beck, Elizabeth M. ; Harris, Anthony...
Journal of Medicinal Chemistry.  60 (2017)  23 - p. 9860-9873 , 2017
Link: https://doi.org/10.1021/..
 
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14

Casein Kinase 1δ/ε Inhibitor PF-5006739 Attenuates Opioid D..:

Wager, Travis T. ; Chandrasekaran, Ramalakshmi Y. ; Bradley, Jenifer...
ACS Chemical Neuroscience.  5 (2014)  12 - p. 1253-1265 , 2014
Link: https://doi.org/10.1021/..
 
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15

Siderophore Receptor-Mediated Uptake of Lactivicin Analogue..:

Starr, Jeremy ; Brown, Matthew F. ; Aschenbrenner, Lisa...
Journal of Medicinal Chemistry.  57 (2014)  9 - p. 3845-3855 , 2014
Link: https://doi.org/10.1021/..
 
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