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Kume, Masaharu
31  results:
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1

Discovery of naldemedine: A potent and orally available opi..:

Inagaki, Masanao ; Kume, Masaharu ; Tamura, Yoshinori...
Bioorganic & Medicinal Chemistry Letters.  29 (2019)  1 - p. 73-77 , 2019
Link: https://doi.org/10.1016/..
 
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2

Discovery of NR2B-selective antagonists via scaffold hoppin..:

Anan, Kosuke ; Masui, Moriyasu ; Tazawa, Aya...
Bioorganic & Medicinal Chemistry Letters.  29 (2019)  9 - p. 1143-1147 , 2019
Link: https://doi.org/10.1016/..
 
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3

Pyrrolinone derivatives as a new class of P2X3 receptor ant..:

Tobinaga, Hiroyuki ; Kameyama, Takayuki ; Oohara, Miho...
Bioorganic & Medicinal Chemistry Letters.  28 (2018)  13 - p. 2338-2342 , 2018
Link: https://doi.org/10.1016/..
 
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4

Discovery of orally bioavailable cyclohexanol-based NR2B-se..:

Anan, Kosuke ; Masui, Moriyasu ; Hara, Shinichiro...
Bioorganic & Medicinal Chemistry Letters.  27 (2017)  17 - p. 4194-4198 , 2017
Link: https://doi.org/10.1016/..
 
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5

Novel Antibacterial Macrolides:  Synthesis of 15-Membered D..:

Ohara, Takafumi ; Kume, Masaharu ; Narukawa, Yukitoshi...
The Journal of Organic Chemistry.  67 (2002)  26 - p. 9146-9152 , 2002
Link: https://doi.org/10.1021/..
 
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6

Totalsynthese von Chinoxapeptin A–C: Bestimmung der absolut..:

Boger, Dale L. ; Ledeboer, Mark W. ; Kume, Masaharu.
Angewandte Chemie.  111 (1999)  16 - p. 2533-2536 , 1999
Link: https://doi.org/10.1002/..
 
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7

Total Synthesis of Quinoxapeptin A-C: Establishment of Abso..:

Boger, Dale L. ; Ledeboer, Mark W. ; Kume, Masaharu.
Angewandte Chemie International Edition.  38 (1999)  16 - p. 2424-2426 , 1999
Link: https://doi.org/10.1002/..
 
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8

Total Synthesis of Luzopeptins A−C:

Boger, Dale L. ; Ledeboer, Mark W. ; Kume, Masaharu
Journal of the American Chemical Society.  121 (1999)  5 - p. 1098-1099 , 1999
Link: https://doi.org/10.1021/..
 
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9

Total Synthesis and Comparative Evaluation of Luzopeptin A−..:

Boger, Dale L. ; Ledeboer, Mark W. ; Kume, Masaharu..
Journal of the American Chemical Society.  121 (1999)  49 - p. 11375-11383 , 1999
Link: https://doi.org/10.1021/..
 
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10

Efficient and practical synthesis of 1⊝methylcarbapenems:

Kume, Masaharu ; Ooka, Hiroaki ; Ishitobi, Hiroyuki
Tetrahedron.  53 (1997)  5 - p. 1635-1646 , 1997
Link: https://doi.org/10.1016/..
 
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11

Novel and efficient synthesis of 1β-methylcarbapenems utili..:

Kume, Masaharu ; Kubota, Tadatoshi ; Iso, Yasuyoshi
Tetrahedron Letters.  36 (1995)  44 - p. 8043-8046 , 1995
Link: https://doi.org/10.1016/..
 
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12

Enzymatic Hydrolyses of the σ-Symmetric Dicarboxylic Dieste..:

Tamai, Satoshi ; Miyauchi, Satoru ; Morizane, Chikako...
Chemistry Letters.  23 (1994)  12 - p. 2381-2384 , 1994
Link: https://doi.org/10.1246/..
 
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13

Orally active cephalosporins. II. Synthesis and structure-a..:

KUME, MASAHARU ; KUBOTA, TADATOSHI ; KIMURA, YASUO...
The Journal of Antibiotics.  46 (1993)  1 - p. 177-192 , 1993
Link: https://doi.org/10.7164/..
 
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14

Orally Active Cephalosporins. IV. Synthesis, Antibacterial ..:

KUME, Masaharu ; KUBOTA, Tadatoshi ; KIMURA, Yasuo..
Chemical and Pharmaceutical Bulletin.  41 (1993)  4 - p. 758-762 , 1993
Link: https://doi.org/10.1248/..
 
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15

Orally active cephalosporins. III. Synthesis and structure-..:

KUME, MASAHARU ; KUBOTA, TADATOSHI ; KIMURA, YASUO..
The Journal of Antibiotics.  46 (1993)  2 - p. 316-330 , 1993
Link: https://doi.org/10.7164/..
 
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