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Kyle R. Brimacombe
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1

Report of the Assay Guidance Workshop on 3-Dimensional Tiss..:

Jordan, Robert ; Ford-Scheimer, Stephanie L ; Alarcon, Rodolfo M...
The Journal of Infectious Diseases.  , 2023
Link: https://doi.org/10.1093/..
 
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2

The NCATS Assay Guidance Manual programme: advancing the pr..:

Markossian, Sarine ; Brimacombe, Kyle R. ; Sittampalam, G. Sitta...
Nature Reviews Drug Discovery.  21 (2022)  12 - p. 863-864 , 2022
Link: https://doi.org/10.1038/..
 
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3

Report of the National Institutes of Health SARS-CoV-2 Anti..:

Hall, Matthew D ; Anderson, James M ; Anderson, Annaliesa...
The Journal of Infectious Diseases.  224 (2021)  Supplement_1 - p. S1-S21 , 2021
Link: https://doi.org/10.1093/..
 
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4

Discovery and Optimization of 2H-1λ2-Pyridin-2-one Inhibito..:

Rohde, Jason M. ; Karavadhi, Surendra ; Pragani, Rajan...
Journal of Medicinal Chemistry.  64 (2021)  8 - p. 4913-4946 , 2021
Link: https://doi.org/10.1021/..
 
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5

Optimization of ether and aniline based inhibitors of lacta..:

Christov, Plamen P. ; Kim, Kwangho ; Jana, Somnath...
Bioorganic & Medicinal Chemistry Letters.  41 (2021)  - p. 127974 , 2021
Link: https://doi.org/10.1016/..
 
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6

Correction: Inhibition of glutathione peroxidase mediates t..:

Hall, Matthew D. ; Marshall, Travis S. ; Kwit, Alexandra D.T....
Journal of Biological Chemistry.  295 (2020)  13 - p. 4370 , 2020
Link: https://doi.org/10.1074/..
 
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7

Retraction of "Collateral Sensitivity of Multidrug-Resistan..:

Goldsborough, Andrew S. ; Handley, Misty D. ; Dulcey, Andres E....
Journal of Medicinal Chemistry.  63 (2020)  3 - p. 1443-1443 , 2020
Link: https://doi.org/10.1021/..
 
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8

Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimi..:

Rai, Ganesha ; Urban, Daniel J. ; Mott, Bryan T....
Journal of Medicinal Chemistry.  63 (2020)  19 - p. 10984-11011 , 2020
Link: https://doi.org/10.1021/..
 
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9

Discovery and optimization of piperazine-1-thiourea-based h..:

Rohde, Jason M. ; Brimacombe, Kyle R. ; Liu, Li...
Bioorganic & Medicinal Chemistry.  26 (2018)  8 - p. 1727-1739 , 2018
Link: https://doi.org/10.1016/..
 
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10

High-throughput screening with nucleosome substrate identif..:

Coussens, Nathan P. ; Kales, Stephen C. ; Henderson, Mark J....
Journal of Biological Chemistry.  293 (2018)  35 - p. 13750-13765 , 2018
Link: https://doi.org/10.1074/..
 
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11

Discovery and Optimization of Potent, Cell-Active Pyrazole-..:

Rai, Ganesha ; Brimacombe, Kyle R. ; Mott, Bryan T....
Journal of Medicinal Chemistry.  60 (2017)  22 - p. 9184-9204 , 2017
Link: https://doi.org/10.1021/..
 
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12

PKM2 activation sensitizes cancer cells to growth inhibitio..:

Tee, Sui Seng ; Park, Jae Mo ; Hurd, Ralph E....
Oncotarget.  8 (2017)  53 - p. 90959-90968 , 2017
Link: https://doi.org/10.18632..
 
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13

Assessing inhibitors of mutant isocitrate dehydrogenase usi..:

Urban, Daniel J. ; Martinez, Natalia J. ; Davis, Mindy I....
Scientific Reports.  7 (2017)  1 - p. , 2017
Link: https://doi.org/10.1038/..
 
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14

A high-content imaging-based screening pipeline for the sys..:

Kubben, Nard ; Brimacombe, Kyle R. ; Donegan, Megan..
Methods.  96 (2016)  - p. 46-58 , 2016
Link: https://doi.org/10.1016/..
 
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15

Small Molecule Inhibitor of NRF2 Selectively Intervenes The..:

Singh, Anju ; Venkannagari, Sreedhar ; Oh, Kyu H....
ACS Chemical Biology.  11 (2016)  11 - p. 3214-3225 , 2016
Link: https://doi.org/10.1021/..
 
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