E-LIB Suche - Ergebnisse für: LaMarche, Matthew J.

1

Application of artificial intelligence and machine learning..:

Kombo, David C. ; LaMarche, Matthew J. ; Konkankit, Chilaluck C..
Proteins: Structure, Function, and Bioinformatics. , 2024

Link: https://doi.org/10.1002/..

2

Predictions of Colloidal Molecular Aggregation Using AI/ML ..:

Kombo, David C. ; Stepp, J. David ; Lim, Sungtaek...
ACS Omega. 9 (2024) 26 - p. 28691-28706 , 2024

Link: https://doi.org/10.1021/..

3

Discovery of Darovasertib (NVP-LXS196), a Pan-PKC Inhibitor..:

Visser, Michael ; Papillon, Julien P. N. ; Luzzio, Michael...
Journal of Medicinal Chemistry. 67 (2024) 2 - p. 1447-1459 , 2024

Link: https://doi.org/10.1021/..

4

Think Biologically, Act Chemically: Miniperspective:

LaMarche, Matthew J.
Journal of Medicinal Chemistry. 65 (2022) 17 - p. 11478-11484 , 2022

Link: https://doi.org/10.1021/..

5

Time-resolved phosphoproteomics reveals scaffolding and cat..:

Vemulapalli, Vidyasiri ; Chylek, Lily A ; Erickson, Alison...
eLife. 10 (2021) - p. , 2021

Link: https://doi.org/10.7554/..

6

Identification of TNO155, an Allosteric SHP2 Inhibitor for ..:

LaMarche, Matthew J. ; Acker, Michael ; Argintaru, Andreea...
Journal of Medicinal Chemistry. 63 (2020) 22 - p. 13578-13594 , 2020

Link: https://doi.org/10.1021/..

7

Resistance to allosteric SHP2 inhibition in FGFR-driven can..:

Lu, Hengyu ; Liu, Chen ; Huynh, Hung...
Oncotarget. 11 (2020) 3 - p. 265-281 , 2020

Link: https://doi.org/10.18632..

8

Correction to Optimization of Fused Bicyclic Allosteric SHP..:

Bagdanoff, Jeffrey T. ; Chen, Zhouliang ; Acker, Michael...
Journal of Medicinal Chemistry. 62 (2019) 7 - p. 3780-3780 , 2019

Link: https://doi.org/10.1021/..

9

6-Amino-3-methylpyrimidinones as Potent, Selective, and Ora..:

Sarver, Patrick ; Acker, Michael ; Bagdanoff, Jeffrey T....
Journal of Medicinal Chemistry. 62 (2019) 4 - p. 1793-1802 , 2019

Link: https://doi.org/10.1021/..

10

Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors:

Bagdanoff, Jeffrey T. ; Chen, Zhouliang ; Acker, Michael...
Journal of Medicinal Chemistry. 62 (2019) 4 - p. 1781-1792 , 2019

Link: https://doi.org/10.1021/..

11

Structural reorganization of SHP2 by oncogenic mutations an..:

LaRochelle, Jonathan R. ; Fodor, Michelle ; Vemulapalli, Vidyasiri...
Nature Communications. 9 (2018) 1 - p. , 2018

Link: https://doi.org/10.1038/..

12

Dual Allosteric Inhibition of SHP2 Phosphatase:

Fodor, Michelle ; Price, Edmund ; Wang, Ping...
ACS Chemical Biology. 13 (2018) 3 - p. 647-656 , 2018

Link: https://doi.org/10.1021/..

13

Identification of an allosteric benzothiazolopyrimidone inh..:

LaRochelle, Jonathan R. ; Fodor, Michelle ; Ellegast, Jana M....
Bioorganic & Medicinal Chemistry. 25 (2017) 24 - p. 6479-6485 , 2017

Link: https://doi.org/10.1016/..

14

Allosteric inhibition of SHP2 phosphatase inhibits cancers ..:

Chen, Ying-Nan P. ; LaMarche, Matthew J. ; Chan, Ho Man...
Nature. 535 (2016) 7610 - p. 148-152 , 2016

Link: https://doi.org/10.1038/..

15

Structural and Functional Consequences of Three Cancer-Asso..:

LaRochelle, Jonathan R. ; Fodor, Michelle ; Xu, Xiang...
Biochemistry. 55 (2016) 15 - p. 2269-2277 , 2016

Link: https://doi.org/10.1021/..