E-LIB Suche - Ergebnisse für: Lamont, Gillian M.

1

Discovery of a Series of Orally Bioavailable Androgen Recep..:

Bagal, Sharan K. ; Astles, Peter C. ; Diène, Coura...
Journal of Medicinal Chemistry. , 2024

2

Development of a Series of Pyrrolopyridone MAT2A Inhibitors:

Atkinson, Stephen J. ; Bagal, Sharan K. ; Argyrou, Argyrides...
Journal of Medicinal Chemistry. 67 (2024) 6 - p. 4541-4559 , 2024

Link: https://doi.org/10.1021/..

3

Chemical Biology Approaches Confirm MCT4 as the Therapeutic..:

Kawatkar, Aarti ; Clark, Roger A. ; Hopcroft, Lorna...
ACS Chemical Biology. 18 (2023) 2 - p. 296-303 , 2023

Link: https://doi.org/10.1021/..

4

Discovery of AZD4747, a Potent and Selective Inhibitor of M..:

Kettle, Jason G. ; Bagal, Sharan K. ; Barratt, Derek...
Journal of Medicinal Chemistry. 66 (2023) 13 - p. 9147-9160 , 2023

Link: https://doi.org/10.1021/..

5

Optimization of hERG and Pharmacokinetic Properties for Bas..:

Goldberg, Frederick W. ; Ting, Attilla K. T. ; Beattie, David...
ACS Medicinal Chemistry Letters. 13 (2022) 8 - p. 1295-1301 , 2022

Link: https://doi.org/10.1021/..

6

Discovery of Clinical Candidate AZD0095, a Selective Inhibi..:

Goldberg, Frederick W. ; Kettle, Jason G. ; Lamont, Gillian M....
Journal of Medicinal Chemistry. 66 (2022) 1 - p. 384-397 , 2022

Link: https://doi.org/10.1021/..

7

The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a..:

Goldberg, Frederick W. ; Finlay, M. Raymond V. ; Ting, Attilla K. T....
Journal of Medicinal Chemistry. 63 (2019) 7 - p. 3461-3471 , 2019

Link: https://doi.org/10.1021/..

8

AZD7648 is a potent and selective DNA-PK inhibitor that enh..:

Fok, Jacqueline H. L. ; Ramos-Montoya, Antonio ; Vazquez-Chantada, Mercedes...
Nature Communications. 10 (2019) 1 - p. , 2019

Link: https://doi.org/10.1038/..

9

Synthesis of 3-(Hetero)aryl Tetrahydropyrazolo[3,4-c]pyridi..:

Kemmitt, Paul D. ; Blades, Kevin ; Box, Matthew R....
The Journal of Organic Chemistry. 79 (2014) 16 - p. 7682-7688 , 2014

Link: https://doi.org/10.1021/..

10

Identification and optimisation of 7-azaindole PAK1 inhibit..:

McCoull, William ; Hennessy, Edward J. ; Blades, Kevin...
Med. Chem. Commun.. 5 (2014) 10 - p. 1533-1539 , 2014

Link: https://doi.org/10.1039/..

11

Sulfonyl-morpholino-pyrimidines: SAR and development of a n..:

Finlay, M. Raymond V. ; Buttar, David ; Critchlow, Susan E....
Bioorganic & Medicinal Chemistry Letters. 22 (2012) 12 - p. 4163-4168 , 2012

Link: https://doi.org/10.1016/..

12

Optimized scale up of 3-pyrimidinylpyrazolo[1,5-a]pyridine ..:

Bethel, Paul A. ; Campbell, Andrew D. ; Goldberg, Frederick W....
Tetrahedron. 68 (2012) 27-28 - p. 5434-5444 , 2012

Link: https://doi.org/10.1016/..

13

Metabolism-driven in vitro/in vivo disconnect of an oral ER..:

Hayhow, Thomas G. ; Williamson, Beth ; Lawson, Mandy...
Communications Biology. 7 (2024) 1 - p. , 2024

Link: https://doi.org/10.1038/..

14

Discovery of a Potent and Selective EGFR Inhibitor (AZD9291..:

Finlay, M. Raymond V. ; Anderton, Mark ; Ashton, Susan...
Journal of Medicinal Chemistry. 57 (2014) 20 - p. 8249-8267 , 2014

Link: https://doi.org/10.1021/..

15

AZD7648 is a potent and selective DNA-PK inhibitor that enh..:

Jacqueline H. L. Fok ; Antonio Ramos-Montoya ; Mercedes Vazquez-Chantada...
https://doi.org/10.1038/s41467-019-12836-9. , 2019

Link: https://doi.org/10.1038/..