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Lapham, Kimberly
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1

Is CYP3A4 induction a good indicator for CYP2CS in cryopres..:

Lapham, Kimberly ; Lin, Zhiwu ; Burchett, Woodrow
Drug Metabolism and Pharmacokinetics.  55 (2024)  - p. 100884 , 2024
Link: https://doi.org/10.1016/..
 
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2

Improved PBPK model of carbamazepine as a strong CYP3A indu..:

Lin, Jian ; Lin, Zhiwu ; Johnson, Nathaniel..
Drug Metabolism and Pharmacokinetics.  55 (2024)  - p. 100885 , 2024
Link: https://doi.org/10.1016/..
 
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3

Discovery of High-Affinity Small-Molecule Binders of the Ep..:

Londregan, Allyn T. ; Aitmakhanova, Karlygash ; Bennett, James...
Journal of Medicinal Chemistry.  66 (2022)  1 - p. 460-472 , 2022
Link: https://doi.org/10.1021/..
 
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4

Evidence-based strategies for the characterisation of human..:

Miners, John O. ; Rowland, Andrew ; Novak, Jonathan J...
Pharmacology & Therapeutics.  218 (2021)  - p. 107689 , 2021
Link: https://doi.org/10.1016/..
 
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5

P100 - In vitro evaluation of UDP-glucuronosyltransferase (..:

Lapham, Kimberly ; Ferguson, Nicholas ; Novak, Jonathan..
Drug Metabolism and Pharmacokinetics.  35 (2020)  1 - p. S52-S53 , 2020
Link: https://doi.org/10.1016/..
 
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6

In vitro characterization of ertugliflozin glucuronidation:

Lapham, Kimberly ; Callegari, Ernesto ; Lin, Jian...
Drug Metabolism and Pharmacokinetics.  34 (2019)  1 - p. S24 , 2019
Link: https://doi.org/10.1016/..
 
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7

Global Portrait of Protein Targets of Metabolites of the Ne..:

Huang, Zhen ; Ogasawara, Daisuke ; Seneviratne, Uthpala I....
ACS Chemical Biology.  14 (2019)  2 - p. 192-197 , 2019
Link: https://doi.org/10.1021/..
 
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8

Industry standard UGT1A3 probe substrate CDCA: A second loo:

Novak, Jonathan J. ; Lin, Jian ; Riccardi, Keith..
Drug Metabolism and Pharmacokinetics.  33 (2018)  1 - p. S29-S30 , 2018
Link: https://doi.org/10.1016/..
 
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9

Design and Synthesis of Clinical Candidate PF-06751979: A P..:

O'Neill, Brian T. ; Beck, Elizabeth M. ; Butler, Christopher R....
Journal of Medicinal Chemistry.  61 (2018)  10 - p. 4476-4504 , 2018
Link: https://doi.org/10.1021/..
 
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10

Enantioselective glucuronidation of lorazepam by UGT2B7 and..:

Lin, Jian ; Niosi, Mark ; Lapham, Kimberly..
Drug Metabolism and Pharmacokinetics.  33 (2018)  1 - p. S27 , 2018
Link: https://doi.org/10.1016/..
 
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11

Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Enga..:

Butler, Christopher R. ; Ogilvie, Kevin ; Martinez-Alsina, Luis...
Journal of Medicinal Chemistry.  60 (2016)  1 - p. 386-402 , 2016
Link: https://doi.org/10.1021/..
 
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12

Inhibition of Hepatobiliary Transport Activity by the Antib..:

Lapham, Kimberly ; Novak, Jonathan ; Marroquin, Lisa D....
Chemical Research in Toxicology.  29 (2016)  10 - p. 1778-1788 , 2016
Link: https://doi.org/10.1021/..
 
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13

Discovery of PF-5190457, a Potent, Selective, and Orally Bi..:

Bhattacharya, Samit K. ; Andrews, Kim ; Beveridge, Ramsay...
ACS Medicinal Chemistry Letters.  5 (2014)  5 - p. 474-479 , 2014
Link: https://doi.org/10.1021/..
 
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14

Evaluation and Synthesis of Polar Aryl- and Heteroaryl Spir..:

Orr, Suvi T. M. ; Beveridge, Ramsay ; Bhattacharya, Samit K....
ACS Medicinal Chemistry Letters.  6 (2014)  2 - p. 156-161 , 2014
Link: https://doi.org/10.1021/..
 
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15

Insights into the Novel Hydrolytic Mechanism of a Diethyl 2..:

Ryder, Tim ; Walker, Gregory S. ; Goosen, Theunis C....
Chemical Research in Toxicology.  25 (2012)  10 - p. 2138-2152 , 2012
Link: https://doi.org/10.1021/..
 
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