E-LIB Suche - Ergebnisse für: Le Grand, Darren

1

Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Trans..:

Grand, Darren Le ; Gosling, Martin ; Baettig, Urs...
Journal of Medicinal Chemistry. 64 (2021) 11 - p. 7241-7260 , 2021

2

Development of autotaxin inhibitors: A series of tetrazole ..:

Thomson, Christopher G. ; Le Grand, Darren ; Dowling, Mark...
Bioorganic & Medicinal Chemistry Letters. 31 (2021) - p. 127663 , 2021

Link: https://doi.org/10.1016/..

3

Deazaflavin Inhibitors of TDP2 with Cellular Activity Can A..:

Komulainen, Emilia ; Pennicott, Lewis ; Le Grand, Darren.
ACS Chemical Biology. 14 (2019) 6 - p. 1110-1114 , 2019

Link: https://doi.org/10.1021/..

4

Development of autotaxin inhibitors: A series of zinc bindi..:

Thomson, Christopher G. ; Le Grand, Darren ; Dowling, Mark...
Bioorganic & Medicinal Chemistry Letters. 28 (2018) 13 - p. 2279-2284 , 2018

Link: https://doi.org/10.1016/..

5

A first generation inhibitor of human Greatwall kinase, ena..:

Ocasio, Cory A. ; Rajasekaran, Mohan B. ; Walker, Sarah...
Oncotarget. 7 (2016) 44 - p. 71182-71197 , 2016

Link: https://doi.org/10.18632..

6

Development of isoform selective PI3-kinase inhibitors as p..:

Bruce, Ian ; Akhlaq, Mohammed ; Bloomfield, Graham C....
Bioorganic & Medicinal Chemistry Letters. 22 (2012) 17 - p. 5445-5450 , 2012

Link: https://doi.org/10.1016/..

7

The discovery of orally available thrombin inhibitors: Opti..:

Ambler, John ; Bentley, David ; Brown, Lyndon...
Bioorganic & Medicinal Chemistry Letters. 9 (1999) 8 - p. 1103-1108 , 1999

Link: https://doi.org/10.1016/..

8

Studies towards the identification of potent, selective and..:

Ambler, John ; Baker, Emma ; Bentley, Dave...
Bioorganic & Medicinal Chemistry Letters. 9 (1999) 5 - p. 737-742 , 1999

Link: https://doi.org/10.1016/..

9

The Discovery of orally available thrombin inhibitors : Stu..:

Ambler, John ; Baker, Emma ; Brown, Lyndon...
Bioorganic & Medicinal Chemistry Letters. 8 (1998) 24 - p. 3583-3588 , 1998

Link: https://doi.org/10.1016/..

10

Deazaflavin inhibitors of TDP2 with cellular activity can a..:

Komulainen, Emilia ; Pennicott, Lewis ; Grand, Darren Le.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613159/. , 2019

Link: http://www.ncbi.nlm.nih...

11

A first generation inhibitor of human Greatwall kinase, ena..:

Ocasio, Cory A ; Rajasekaran, Mohan B ; Walker, Sarah...
http://sro.sussex.ac.uk/id/eprint/63037/1/11511-174023-1-PB.pdf. , 2016

Link: http://sro.sussex.ac.uk/..

12

A first generation inhibitor of human Greatwall kinase, ena..:

Cory A Ocasio ; Mohan Rajasekaran ; Sarah Walker...
10779/uos.23433059.v2. , 2016

Link: https://figshare.com/art..

13

Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Trans..:

Darren Le Grand (10864828) ; Martin Gosling (571081) ; Urs Baettig (1663810)...
https://figshare.com/articles/journal_contribution/Discovery_of_Icenticaftor_QBW251_a_Cystic_Fibrosis_Transmembrane_Conductance_Regulator_Potentiator_with_Clinical_Efficacy_in_Cystic_Fibrosis_and_Chronic_Obstructive_Pulmonary_Disease/14664763. , 2021

Link: https://doi.org/10.1021/..

14

Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Trans..:

Darren Le Grand (10864828) ; Martin Gosling (571081) ; Urs Baettig (1663810)...
https://figshare.com/articles/dataset/Discovery_of_Icenticaftor_QBW251_a_Cystic_Fibrosis_Transmembrane_Conductance_Regulator_Potentiator_with_Clinical_Efficacy_in_Cystic_Fibrosis_and_Chronic_Obstructive_Pulmonary_Disease/14664760. , 2021

Link: https://doi.org/10.1021/..

15

Molecular Analysis at Relapse of Patients Treated on the Ib..:

Sarma, Anita ; Evans, Charlotte ; Dalal, Surita...
https://hull-repository.worktribe.com/output/4519308. , 2023

Link: https://hull-repository...