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Leidner, Florian
38  results:
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1

Regulation of the fungal fatty acid synthase through confor..:

Leidner, Florian ; Grubmuller, Helmut
Biophysical Journal.  122 (2023)  3 - p. 186a , 2023
Link: https://doi.org/10.1016/..
 
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2

Deciphering Complex Mechanisms of Resistance and Loss of Po..:

Leidner, Florian ; Kurt Yilmaz, Nese ; Schiffer, Celia A.
Journal of Chemical Theory and Computation.  17 (2021)  4 - p. 2054-2064 , 2021
Link: https://doi.org/10.1021/..
 
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3

Deciphering Antifungal Drug Resistance in Pneumocystis jiro..:

Leidner, Florian ; Kurt Yilmaz, Nese ; Schiffer, Celia A.
Journal of Chemical Information and Modeling.  61 (2021)  6 - p. 2537-2541 , 2021
Link: https://doi.org/10.1021/..
 
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4

Drug Design Strategies to Avoid Resistance in Direct-Acting..:

Matthew, Ashley N. ; Leidner, Florian ; Lockbaum, Gordon J....
Chemical Reviews.  121 (2021)  6 - p. 3238-3270 , 2021
Link: https://doi.org/10.1021/..
 
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5

Molecular Mechanisms of Drug Resistance in HIV-1 Protease:

Leidner, Florian , 2020
Link: https://nbn-resolving.de..
 
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6

Molecular Determinants of Epistasis in HIV-1 Protease: Eluc..:

Henes, Mina ; Kosovrasti, Klajdi ; Lockbaum, Gordon J....
Biochemistry.  58 (2019)  35 - p. 3711-3726 , 2019
Link: https://doi.org/10.1021/..
 
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7

Correction to Structural Adaptation of Darunavir Analogues ..:

Lockbaum, Gordon J. ; Leidner, Florian ; Rusere, Linah N....
ACS Infectious Diseases.  5 (2019)  6 - p. 1044-1044 , 2019
Link: https://doi.org/10.1021/..
 
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8

Picomolar to Micromolar: Elucidating the Role of Distal Mut..:

Henes, Mina ; Lockbaum, Gordon J. ; Kosovrasti, Klajdi...
ACS Chemical Biology.  14 (2019)  11 - p. 2441-2452 , 2019
Link: https://doi.org/10.1021/..
 
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9

Molecular and Structural Mechanism of Pan-Genotypic HCV NS3..:

Timm, Jennifer ; Kosovrasti, Klajdi ; Henes, Mina...
ACS Chemical Biology.  15 (2019)  2 - p. 342-352 , 2019
Link: https://doi.org/10.1021/..
 
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10

Target-Specific Prediction of Ligand Affinity with Structur..:

Leidner, Florian ; Kurt Yilmaz, Nese ; Schiffer, Celia A.
Journal of Chemical Information and Modeling.  59 (2019)  9 - p. 3679-3691 , 2019
Link: https://doi.org/10.1021/..
 
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11

pM to μM: Elucidating the Interdependence of Highly Resista..:

Lockbaum, Gordon J ; Henes, Mina ; Leidner, Florian...
The FASEB Journal.  33 (2019)  S1 - p. , 2019
Link: https://doi.org/10.1096/..
 
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12

Hydration Structure and Dynamics of Inhibitor-Bound HIV-1 P..:

Leidner, Florian ; Kurt Yilmaz, Nese ; Paulsen, Janet..
Journal of Chemical Theory and Computation.  14 (2018)  5 - p. 2784-2796 , 2018
Link: https://doi.org/10.1021/..
 
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13

Molecular Mechanism of Resistance in a Clinically Significa..:

Matthew, Ashley N. ; Leidner, Florian ; Newton, Alicia...
Structure.  26 (2018)  10 - p. 1360-1372.e5 , 2018
Link: https://doi.org/10.1016/..
 
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14

Structural analysis of the active site and DNA binding of h..:

Hou, Shurong ; Silvas, Tania V. ; Leidner, Florian...
The FASEB Journal.  32 (2018)  S1 - p. , 2018
Link: https://doi.org/10.1096/..
 
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15

Structural Analysis of Darunavir Analogs Against Primary Re..:

Lockbaum, Gordon Joseph ; Leidner, Florian ; Rusere, Linah...
The FASEB Journal.  32 (2018)  S1 - p. , 2018
Link: https://doi.org/10.1096/..
 
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