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Leit, Silvana
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1

Discovery of a Potent and Selective Tyrosine Kinase 2 Inhib..:

Leit, Silvana ; Greenwood, Jeremy ; Carriero, Samantha...
Journal of Medicinal Chemistry.  66 (2023)  15 - p. 10473-10496 , 2023
Link: https://doi.org/10.1021/..
 
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2

Targeting the Cbl-b-Notch1 axis as a novel immunotherapeuti..:

Monticone, Giulia ; Huang, Zhi ; Csibi, Fred...
Frontiers in Immunology.  13 (2022)  - p. , 2022
Link: https://doi.org/10.3389/..
 
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3

Potent and selective TYK2-JH1 inhibitors highly efficacious..:

Leit, Silvana ; Greenwood, Jeremy R. ; Mondal, Sayan...
Bioorganic & Medicinal Chemistry Letters.  73 (2022)  - p. 128891 , 2022
Link: https://doi.org/10.1016/..
 
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4

Preclinical evaluation of tyrosine kinase 2 inhibitors for ..:

Coomans de Brachène, Alexandra ; Castela, Angela ; Op de Beeck, Anne...
Diabetes, Obesity and Metabolism.  22 (2020)  10 - p. 1827-1836 , 2020
Link: https://doi.org/10.1111/..
 
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5

An allosteric mechanism for potent inhibition of human ATP-..:

Wei, Jia ; Leit, Silvana ; Kuai, Jun...
Nature.  568 (2019)  7753 - p. 566-570 , 2019
Link: https://doi.org/10.1038/..
 
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6

Novel HDAC6 isoform selective chiral small molecule histone..:

Smil, David V. ; Manku, Sukhdev ; Chantigny, Yves A....
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  3 - p. 688-692 , 2009
Link: https://doi.org/10.1016/..
 
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7

Diphenylmethylene hydroxamic acids as selective class IIa h..:

Tessier, Pierre ; Smil, David V. ; Wahhab, Amal...
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  19 - p. 5684-5688 , 2009
Link: https://doi.org/10.1016/..
 
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8

Sulfamides as novel histone deacetylase inhibitors:

Wahhab, Amal ; Smil, David ; Ajamian, Alain...
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  2 - p. 336-340 , 2009
Link: https://doi.org/10.1016/..
 
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9

SAR and biological evaluation of analogues of a small molec..:

Raeppel, Stéphane ; Zhou, Nancy ; Gaudette, Frédéric...
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  3 - p. 644-649 , 2009
Link: https://doi.org/10.1016/..
 
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10

Discovery of N-(2-Aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-..:

Zhou, Nancy ; Moradei, Oscar ; Raeppel, Stephane...
Journal of Medicinal Chemistry.  51 (2008)  14 - p. 4072-4075 , 2008
Link: https://doi.org/10.1021/..
 
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11

Design and synthesis of 4-[(s-triazin-2-ylamino)methyl]-N-(..:

Paquin, Isabelle ; Raeppel, Stéphane ; Leit, Silvana...
Bioorganic & Medicinal Chemistry Letters.  18 (2008)  3 - p. 1067-1071 , 2008
Link: https://doi.org/10.1016/..
 
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12

4-(Heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and ..:

Fréchette, Sylvie ; Leit, Silvana ; Woo, Soon Hyung...
Bioorganic & Medicinal Chemistry Letters.  18 (2008)  4 - p. 1502-1506 , 2008
Link: https://doi.org/10.1016/..
 
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13

N-(2-Amino-phenyl)-4-(heteroarylmethyl)-benzamides as new h..:

Vaisburg, Arkadii ; Paquin, Isabelle ; Bernstein, Naomy...
Bioorganic & Medicinal Chemistry Letters.  17 (2007)  24 - p. 6729-6733 , 2007
Link: https://doi.org/10.1016/..
 
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14

Substituted N-(2-aminophenyl)-benzamides, (E)-N-(2-aminophe..:

Moradei, Oscar ; Leit, Silvana ; Zhou, Nancy...
Bioorganic & Medicinal Chemistry Letters.  16 (2006)  15 - p. 4048-4052 , 2006
Link: https://doi.org/10.1016/..
 
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15

(2-Amino-phenyl)-amides of ω-substituted alkanoic acids as ..:

Vaisburg, Arkadii ; Bernstein, Naomy ; Frechette, Sylvie...
Bioorganic & Medicinal Chemistry Letters.  14 (2004)  1 - p. 283-287 , 2004
Link: https://doi.org/10.1016/..
 
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