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Litchfield, John
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1

Pharmacological inhibition of IRAK4 kinase activity does no..:

Qiao, Shuxi ; LaViolette, Brianna ; Paulhus, Brianna LaCarubba...
JCSM Rapid Communications.  6 (2023)  2 - p. 122-133 , 2023
Link: https://doi.org/10.1002/..
 
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2

Target occupancy study and whole-body dosimetry with a MAGL..:

Arakawa, Ryosuke ; Takano, Akihiro ; Nag, Sangram...
EJNMMI Research.  12 (2022)  1 - p. , 2022
Link: https://doi.org/10.1186/..
 
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3

Effect of a Ketohexokinase Inhibitor (PF‐06835919) on In Vi..:

Tess, David A. ; Kimoto, Emi ; King‐Ahmad, Amanda...
Clinical Pharmacology & Therapeutics.  112 (2022)  3 - p. 605-614 , 2022
Link: https://doi.org/10.1002/..
 
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4

A Physiologically Based in Silico Tool to Assess the Risk o..:

Li, Zhenhong ; Litchfield, John ; Tess, David A....
Journal of Medicinal Chemistry.  63 (2020)  12 - p. 6489-6498 , 2020
Link: https://doi.org/10.1021/..
 
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5

Estimation of the Effect of OAT2-Mediated Active Uptake on ..:

Li, Rui ; Mathialagan, Sumathy ; Novak, Jonathan J....
The AAPS Journal.  22 (2020)  2 - p. , 2020
Link: https://doi.org/10.1208/..
 
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6

Structural attributes influencing unbound tissue distributi..:

Orozco, Christine C. ; Atkinson, Karen ; Ryu, Sangwoo...
European Journal of Medicinal Chemistry.  185 (2020)  - p. 111813 , 2020
Link: https://doi.org/10.1016/..
 
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7

Predicting the Human Hepatic Clearance of Acidic and Zwitte..:

Tess, David A. ; Eng, Heather ; Kalgutkar, Amit S....
Journal of Medicinal Chemistry.  63 (2020)  20 - p. 11831-11844 , 2020
Link: https://doi.org/10.1021/..
 
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8

Discovery of Diphenylacetamides as CXCR7 Inhibitors with No..:

Menhaji-Klotz, Elnaz ; Ward, Jessica ; Brown, Janice A....
ACS Medicinal Chemistry Letters.  11 (2020)  6 - p. 1330-1334 , 2020
Link: https://doi.org/10.1021/..
 
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9

Global Portrait of Protein Targets of Metabolites of the Ne..:

Huang, Zhen ; Ogasawara, Daisuke ; Seneviratne, Uthpala I....
ACS Chemical Biology.  14 (2019)  2 - p. 192-197 , 2019
Link: https://doi.org/10.1021/..
 
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10

Effect of Hepatic Organic Anion‐Transporting Polypeptide 1B..:

Bergman, Arthur ; Bi, Yi‐an ; Mathialagan, Sumathy...
Clinical Pharmacology & Therapeutics.  106 (2019)  4 - p. 792-802 , 2019
Link: https://doi.org/10.1002/..
 
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11

Metabolism of PF-04958242: Substrate concentration-dependen..:

Obach, R. Scott ; Doran, Angela C. ; Shaffer, Christopher L..
Drug Metabolism and Pharmacokinetics.  33 (2018)  1 - p. S47 , 2018
Link: https://doi.org/10.1016/..
 
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12

Discovery of a Novel Small-Molecule Modulator of C–X–C Chem..:

Menhaji-Klotz, Elnaz ; Hesp, Kevin D. ; Londregan, Allyn T....
Journal of Medicinal Chemistry.  61 (2018)  8 - p. 3685-3696 , 2018
Link: https://doi.org/10.1021/..
 
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13

Identification of a novel conformationally constrained gluc..:

Lee, Esther C.Y. ; Tu, Meihua ; Stevens, Benjamin D....
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  3 - p. 839-844 , 2014
Link: https://doi.org/10.1016/..
 
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14

Mediastinal pancreatic pseudocyst with hemorrhage and left ..:

Brahmbhatt, Parag ; McKinney, Jason ; Litchfield, John...
Gastroenterology Report.  4 (2014)  3 - p. 241-245 , 2014
Link: https://doi.org/10.1093/..
 
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15

The Relationship of Glucokinase Activator–induced Hypoglyce..:

Pettersen, John C. ; Litchfield, John ; Neef, Natasha...
Toxicologic Pathology.  42 (2014)  4 - p. 696-708 , 2014
Link: https://doi.org/10.1177/..
 
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