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Lo, Mei-Chu
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1

Creating a more strategic small molecule biophysical hit ch..:

Fotsch, Christopher ; Basu, Debaleena ; Case, Ryan...
SLAS Discovery.  29 (2024)  4 - p. 100159 , 2024
Link: https://doi.org/10.1016/..
 
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2

Imidazolone as an Amide Bioisostere in the Development of β..:

Jackson, Jeffrey J. ; Siegmund, Aaron C. ; Bai, Wen-Ju...
Journal of Medicinal Chemistry.  66 (2023)  23 - p. 16120-16140 , 2023
Link: https://doi.org/10.1021/..
 
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3

An Automated High-Throughput Fluorescence In Situ Hybridiza..:

Dou, Hui H. ; Mallari, Rommel ; Pipathsouk, Andrew..
SLAS Discovery.  26 (2021)  2 - p. 281-291 , 2021
Link: https://doi.org/10.1177/..
 
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4

Structures and mechanism of human glycosyltransferase β1,3-..:

Hao, Yue ; Créquer-Grandhomme, Amandine ; Javier, Noelle...
Journal of Biological Chemistry.  296 (2021)  - p. 100042 , 2021
Link: https://doi.org/10.1074/..
 
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5

Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhib..:

Rescourio, Gwenaella ; Gonzalez, Ana Z. ; Jabri, Salman...
Journal of Medicinal Chemistry.  62 (2019)  22 - p. 10258-10271 , 2019
Link: https://doi.org/10.1021/..
 
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6

A "Click Chemistry Platform" for the Rapid Synthesis of Bis..:

Wurz, Ryan P. ; Dellamaggiore, Ken ; Dou, Hannah...
Journal of Medicinal Chemistry.  61 (2017)  2 - p. 453-461 , 2017
Link: https://doi.org/10.1021/..
 
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7

Development of a scintillation proximity binding assay for ..:

Meleza, Cesar ; Thomasson, Bobbie ; Ramachandran, Chidambaram...
Analytical Biochemistry.  511 (2016)  - p. 17-23 , 2016
Link: https://doi.org/10.1016/..
 
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8

Development of a nucleotide sugar purification method using..:

Eastwood, Heather ; Xia, Fang ; Lo, Mei-Chu...
Journal of Pharmaceutical and Biomedical Analysis.  115 (2015)  - p. 402-409 , 2015
Link: https://doi.org/10.1016/..
 
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9

Selective and Potent Morpholinone Inhibitors of the MDM2–p5..:

Gonzalez, Ana Z. ; Eksterowicz, John ; Bartberger, Michael D....
Journal of Medicinal Chemistry.  57 (2014)  6 - p. 2472-2488 , 2014
Link: https://doi.org/10.1021/..
 
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10

Discovery of AMG 232, a Potent, Selective, and Orally Bioav..:

Sun, Daqing ; Li, Zhihong ; Rew, Yosup...
Journal of Medicinal Chemistry.  57 (2014)  4 - p. 1454-1472 , 2014
Link: https://doi.org/10.1021/..
 
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11

Discovery of AMG 925, a FLT3 and CDK4 Dual Kinase Inhibitor..:

Li, Zhihong ; Wang, Xianghong ; Eksterowicz, John...
Journal of Medicinal Chemistry.  57 (2014)  8 - p. 3430-3449 , 2014
Link: https://doi.org/10.1021/..
 
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12

Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydr..:

Gonzalez, Ana Z. ; Li, Zhihong ; Beck, Hilary P....
Journal of Medicinal Chemistry.  57 (2014)  7 - p. 2963-2988 , 2014
Link: https://doi.org/10.1021/..
 
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13

Optimization beyond AMG 232: Discovery and SAR of sulfonami..:

Wang, Yingcai ; Zhu, Jiang ; Liu, Jiwen (Jim)...
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  16 - p. 3782-3785 , 2014
Link: https://doi.org/10.1016/..
 
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14

Discovery of AM-7209, a Potent and Selective 4-Amidobenzoic..:

Rew, Yosup ; Sun, Daqing ; Yan, Xuelei...
Journal of Medicinal Chemistry.  57 (2014)  24 - p. 10499-10511 , 2014
Link: https://doi.org/10.1021/..
 
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15

Discovery of Potent and Simplified Piperidinone-Based Inhib..:

Yu, Ming ; Wang, Yingcai ; Zhu, Jiang...
ACS Medicinal Chemistry Letters.  5 (2014)  8 - p. 894-899 , 2014
Link: https://doi.org/10.1021/..
 
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