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Longenecker, Kenton
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1

Minimising the payload solvent exposed hydrophobic surface ..:

Hobson, Adrian D. ; Zhu, Haizhong ; Qiu, Wei..
RSC Medicinal Chemistry.  15 (2024)  3 - p. 832-838 , 2024
Link: https://doi.org/10.1039/..
 
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2

Correction: Minimising the payload solvent exposed hydropho..:

Hobson, Adrian D. ; Zhu, Haizhong ; Qiu, Wei..
RSC Medicinal Chemistry.  15 (2024)  3 - p. 1072-1072 , 2024
Link: https://doi.org/10.1039/..
 
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3

The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent ant..:

Baumgartner, Christina K. ; Ebrahimi-Nik, Hakimeh ; Iracheta-Vellve, Arvin...
Nature.  622 (2023)  7984 - p. 850-862 , 2023
Link: https://doi.org/10.1038/..
 
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4

The HPK1 Inhibitor A-745 Verifies the Potential of Modulati..:

Malchow, Sven ; Korepanova, Alla ; Panchal, Sanjay C....
ACS Chemical Biology.  17 (2022)  3 - p. 556-566 , 2022
Link: https://doi.org/10.1021/..
 
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5

Balancing Properties with Carboxylates: A Lead Optimization..:

Tong, Yunsong ; Florjancic, Alan S. ; Clark, Rick F....
ACS Medicinal Chemistry Letters.  12 (2021)  7 - p. 1108-1115 , 2021
Link: https://doi.org/10.1021/..
 
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6

Complex of human Melanotransferrin and SC57.32 Fab fragment..:

Hayashi, Kristyn ; Longenecker, Kenton L. ; Liu, Yi-Liang...
Scientific Reports.  11 (2021)  1 - p. , 2021
Link: https://doi.org/10.1038/..
 
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7

Development of Orally Efficacious Allosteric Inhibitors of ..:

Dietrich, Justin D. ; Longenecker, Kenton L. ; Wilson, Noel S....
Journal of Medicinal Chemistry.  64 (2020)  1 - p. 417-429 , 2020
Link: https://doi.org/10.1021/..
 
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8

Structure of human DPEP3 in complex with the SC-003 antibod..:

Hayashi, Kristyn ; Longenecker, Kenton L. ; Koenig, Patrick...
Journal of Structural Biology.  211 (2020)  1 - p. 107512 , 2020
Link: https://doi.org/10.1016/..
 
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9

Discovery of N-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5..:

Sheppard, George S. ; Wang, Le ; Fidanze, Steven D....
Journal of Medicinal Chemistry.  63 (2020)  10 - p. 5585-5623 , 2020
Link: https://doi.org/10.1021/..
 
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10

Selective inhibition of the BD2 bromodomain of BET proteins..:

Faivre, Emily J. ; McDaniel, Keith F. ; Albert, Daniel H....
Nature.  578 (2020)  7794 - p. 306-310 , 2020
Link: https://doi.org/10.1038/..
 
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11

Synthesis and Biological Characterization of Aryl Uracil In..:

Randolph, John T. ; Krueger, A. Chris ; Donner, Pamela L....
Journal of Medicinal Chemistry.  61 (2018)  3 - p. 1153-1163 , 2018
Link: https://doi.org/10.1021/..
 
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12

Fragment-based discovery of a potent NAMPT inhibitor:

Korepanova, Alla ; Longenecker, Kenton L. ; Pratt, Steve D....
Bioorganic & Medicinal Chemistry Letters.  28 (2018)  3 - p. 437-440 , 2018
Link: https://doi.org/10.1016/..
 
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13

Crystal structure of full-lengthZika virusNS5 protein revea..:

Upadhyay, Anup K. ; Cyr, Matthew ; Longenecker, Kenton...
Acta Crystallographica Section F Structural Biology Communications.  73 (2017)  3 - p. 116-122 , 2017
Link: https://doi.org/10.1107/..
 
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14

Identification of novel resistance mechanisms to NAMPT inhi..:

Guo, Jun ; Lam, Lloyd T. ; Longenecker, Kenton L....
Biochemical and Biophysical Research Communications.  491 (2017)  3 - p. 681-686 , 2017
Link: https://doi.org/10.1016/..
 
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15

SAR and characterization of non-substrate isoindoline urea ..:

Curtin, Michael L. ; Heyman, H. Robin ; Clark, Richard F....
Bioorganic & Medicinal Chemistry Letters.  27 (2017)  15 - p. 3317-3325 , 2017
Link: https://doi.org/10.1016/..
 
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