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Lupardus, Patrick
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1

Isoform-selective TGF-β3 inhibition for systemic sclerosis:

Sun, Tianhe ; Vander Heiden, Jason A. ; Gao, Xia...
Med.  5 (2024)  2 - p. 132-147.e7 , 2024
Link: https://doi.org/10.1016/..
 
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2

Novel Anti-LY6G6D/CD3 T-Cell–Dependent Bispecific Antibody ..:

Wang, Peiyin ; Sun, Liping L. ; Clark, Robyn...
Molecular Cancer Therapeutics.  21 (2022)  6 - p. 974-985 , 2022
Link: https://doi.org/10.1158/..
 
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3

Structure of a Janus kinase cytokine receptor complex revea..:

Glassman, Caleb R. ; Tsutsumi, Naotaka ; Saxton, Robert A....
Science.  376 (2022)  6589 - p. 163-169 , 2022
Link: https://doi.org/10.1126/..
 
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4

Dramatic activation of an antibody by a single amino acid c..:

Liang, Wei-Ching ; Yin, Jianping ; Lupardus, Patrick...
Scientific Reports.  11 (2021)  1 - p. , 2021
Link: https://doi.org/10.1038/..
 
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5

Structural basis for IL-12 and IL-23 receptor sharing revea..:

Glassman, Caleb R. ; Mathiharan, Yamuna Kalyani ; Jude, Kevin M....
Cell.  184 (2021)  4 - p. 983-999.e24 , 2021
Link: https://doi.org/10.1016/..
 
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6

T cell receptor interactions with human leukocyte antigen g..:

Coles, Charlotte H. ; McMurran, Catriona ; Lloyd, Angharad...
Journal of Biological Chemistry.  295 (2020)  33 - p. 11486-11494 , 2020
Link: https://doi.org/10.1074/..
 
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7

Mutation position is an important determinant for predictin..:

Capietto, Aude-Hélène ; Jhunjhunwala, Suchit ; Pollock, Samuel B....
Journal of Experimental Medicine.  217 (2020)  4 - p. , 2020
Link: https://doi.org/10.1084/..
 
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8

RIP1 inhibition blocks inflammatory diseases but not tumor ..:

Patel, Snahel ; Webster, Joshua D. ; Varfolomeev, Eugene...
Cell Death & Differentiation.  27 (2019)  1 - p. 161-175 , 2019
Link: https://doi.org/10.1038/..
 
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9

Discovery of Potent Benzolactam IRAK4 Inhibitors with Robus..:

Rajapaksa, Naomi S. ; Gobbi, Alberto ; Drobnick, Joy...
ACS Medicinal Chemistry Letters.  11 (2019)  3 - p. 327-333 , 2019
Link: https://doi.org/10.1021/..
 
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10

Potent and selective inhibitors of receptor-interacting pro..:

Hamilton, Gregory L. ; Chen, Huifen ; Deshmukh, Gauri...
Bioorganic & Medicinal Chemistry Letters.  29 (2019)  12 - p. 1497-1501 , 2019
Link: https://doi.org/10.1016/..
 
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11

Development of Potent and Selective Pyrazolopyrimidine IRAK..:

Bryan, Marian C. ; Drobnick, Joy ; Gobbi, Alberto...
Journal of Medicinal Chemistry.  62 (2019)  13 - p. 6223-6240 , 2019
Link: https://doi.org/10.1021/..
 
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12

Discovery of a class of highly potent Janus Kinase 1/2 (JAK..:

Zak, Mark ; Hanan, Emily J. ; Lupardus, Patrick...
Bioorganic & Medicinal Chemistry Letters.  29 (2019)  12 - p. 1522-1531 , 2019
Link: https://doi.org/10.1016/..
 
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13

Receptor-mediated dimerization of JAK2 FERM domains is requ..:

Ferrao, Ryan D ; Wallweber, Heidi JA ; Lupardus, Patrick J
eLife.  7 (2018)  - p. , 2018
Link: https://doi.org/10.7554/..
 
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14

A novel NMDA receptor positive allosteric modulator that ac..:

Wang, Tzu-Ming ; Brown, Brandon M. ; Deng, Lunbin...
Neuropharmacology.  121 (2017)  - p. 204-218 , 2017
Link: https://doi.org/10.1016/..
 
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15

Correction: Corrigendum: A broadly protective therapeutic a..:

Chai, Ning ; Swem, Lee R. ; Park, Summer...
Nature Communications.  8 (2017)  1 - p. , 2017
Link: https://doi.org/10.1038/..
 
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