E-LIB Suche - Ergebnisse für: Lynch, James T.

1

Development of a Series of Pyrrolopyridone MAT2A Inhibitors:

Atkinson, Stephen J. ; Bagal, Sharan K. ; Argyrou, Argyrides...
Journal of Medicinal Chemistry. 67 (2024) 6 - p. 4541-4559 , 2024

Link: https://doi.org/10.1021/..

2

Large-scale Pan-cancer Cell Line Screening Identifies Actio..:

Bashi, Azadeh C. ; Coker, Elizabeth A. ; Bulusu, Krishna C....
Cancer Discovery. 14 (2024) 5 - p. 846-865 , 2024

Link: https://doi.org/10.1158/..

3

mTOR inhibition amplifies the anti-lymphoma effect of PI3Kβ..:

Xu, Wendan ; Berning, Philipp ; Erdmann, Tabea...
Leukemia. 37 (2022) 1 - p. 178-189 , 2022

Link: https://doi.org/10.1038/..

4

AKT-mTORC1 reactivation is the dominant resistance driver f..:

Dunn, Shanade ; Eberlein, Cath ; Yu, Jason...
Oncogene. 41 (2022) 46 - p. 5046-5060 , 2022

Link: https://doi.org/10.1038/..

5

Fragment-Based Design of a Potent MAT2a Inhibitor and in Vi..:

De Fusco, Claudia ; Schimpl, Marianne ; Börjesson, Ulf...
Journal of Medicinal Chemistry. 64 (2021) 10 - p. 6814-6826 , 2021

Link: https://doi.org/10.1021/..

6

Drug mechanism‐of‐action discovery through the integration ..:

Gonçalves, Emanuel ; Segura‐Cabrera, Aldo ; Pacini, Clare...
Molecular Systems Biology. 16 (2020) 7 - p. , 2020

Link: https://doi.org/10.15252..

7

Enhancer Activation by Pharmacologic Displacement of LSD1 f..:

Maiques-Diaz, Alba ; Spencer, Gary J. ; Lynch, James T....
Cell Reports. 22 (2018) 13 - p. 3641-3659 , 2018

Link: https://doi.org/10.1016/..

8

Identification of differential PI3K pathway target dependen..:

Lynch, James T. ; McEwen, Robert ; Crafter, Claire...
Oncotarget. 7 (2016) 16 - p. 22128-22139 , 2016

Link: https://doi.org/10.18632..

9

CD86 expression as a surrogate cellular biomarker for pharm..:

Lynch, James T. ; Cockerill, Mark J. ; Hitchin, James R...
Analytical Biochemistry. 442 (2013) 1 - p. 104-106 , 2013

Link: https://doi.org/10.1016/..

10

The Histone Demethylase KDM1A Sustains the Oncogenic Potent..:

Harris, William J. ; Huang, Xu ; Lynch, James T....
Cancer Cell. 21 (2012) 4 - p. 473-487 , 2012

Link: https://doi.org/10.1016/..

11

The role of glucocorticoid receptor phosphorylation in Mcl-..:

Lynch, James T ; Rajendran, Ramkumar ; Xenaki, Georgia...
Molecular Cancer. 9 (2010) 1 - p. , 2010

Link: https://doi.org/10.1186/..

12

Rotary Vacuum Filtration of Sludge and the Effect of War on..:

Lynch, James T. ; Mann, Uhl T.
Sewage Works Journal. 15 (1943) 5 - p. 807-816 , 1943

Link: https://www.jstor.org/st..

13

mTOR inhibition amplifies the anti-lymphoma effect of PI3Kβ..:

Xu, Wendan ; Berning, Philipp ; Erdmann, Tabea...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883168/. , 2022

Link: http://www.ncbi.nlm.nih...

14

AKT-mTORC1 reactivation is the dominant resistance driver f..:

Dunn, Shanade ; Eberlein, Cath ; Yu, Jason...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652152/. , 2022

Link: http://www.ncbi.nlm.nih...

15

Drug mechanism‐of‐action discovery through the integration ..:

Gonçalves, Emanuel ; Segura‐Cabrera, Aldo ; Pacini, Clare...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336273/. , 2020

Link: http://www.ncbi.nlm.nih...