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Mac Sweeney, Aengus
26  results:
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1

Inverse agonist efficacy of selatogrel blunts constitutive ..:

Pons, Véronique ; Garcia, Cédric ; Tidten-Luksch, Naomi...
Biochemical Pharmacology.  206 (2022)  - p. 115291 , 2022
Link: https://doi.org/10.1016/..
 
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2

Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-..:

Mainolfi, Nello ; Ehara, Takeru ; Karki, Rajeshri G....
Journal of Medicinal Chemistry.  63 (2020)  11 - p. 5697-5722 , 2020
Link: https://doi.org/10.1021/..
 
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3

Small-molecule factor B inhibitor for the treatment of comp..:

Schubart, Anna ; Anderson, Karen ; Mainolfi, Nello...
Proceedings of the National Academy of Sciences.  116 (2019)  16 - p. 7926-7931 , 2019
Link: https://doi.org/10.1073/..
 
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4

Discovery of Novel Inhibitors of LpxC Displaying Potent in ..:

Surivet, Jean-Philippe ; Panchaud, Philippe ; Specklin, Jean-Luc...
Journal of Medicinal Chemistry.  63 (2019)  1 - p. 66-87 , 2019
Link: https://doi.org/10.1021/..
 
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5

Design, Synthesis, and Preclinical Characterization of Sele..:

Karki, Rajeshri G. ; Powers, James ; Mainolfi, Nello...
Journal of Medicinal Chemistry.  62 (2019)  9 - p. 4656-4668 , 2019
Link: https://doi.org/10.1021/..
 
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6

Discovery and Design of First Benzylamine-Based Ligands Bin..:

Vulpetti, Anna ; Ostermann, Nils ; Randl, Stefan...
ACS Medicinal Chemistry Letters.  9 (2018)  5 - p. 490-495 , 2018
Link: https://doi.org/10.1021/..
 
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7

The crystallization additive hexatungstotellurate promotes ..:

Mac Sweeney, Aengus ; Chambovey, Alain ; Wicki, Micha...
PLOS ONE.  13 (2018)  6 - p. e0199639 , 2018
Link: https://doi.org/10.1371/..
 
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8

Discovery of Highly Potent and Selective Small-Molecule Rev..:

Lorthiois, Edwige ; Anderson, Karen ; Vulpetti, Anna...
Journal of Medicinal Chemistry.  60 (2017)  13 - p. 5717-5735 , 2017
Link: https://doi.org/10.1021/..
 
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9

Structure-Based Library Design and Fragment Screening for t..:

Vulpetti, Anna ; Randl, Stefan ; Rüdisser, Simon...
Journal of Medicinal Chemistry.  60 (2017)  5 - p. 1946-1958 , 2017
Link: https://doi.org/10.1021/..
 
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10

Structure-based design and optimization of potent inhibitor..:

Grosche, Philipp ; Sirockin, Finton ; Mac Sweeney, Aengus...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  3 - p. 438-443 , 2015
Link: https://doi.org/10.1016/..
 
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11

Discovery and Structure-Based Optimization of Adenain Inhib..:

Mac Sweeney, Aengus ; Grosche, Philipp ; Ellis, David...
ACS Medicinal Chemistry Letters.  5 (2014)  8 - p. 937-941 , 2014
Link: https://doi.org/10.1021/..
 
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12

The Crystal Structure of E.coli 1-Deoxy-d-xylulose-5-phosph..:

Mac Sweeney, Aengus ; Lange, Roland ; Fernandes, Roberta P.M....
Journal of Molecular Biology.  345 (2005)  1 - p. 115-127 , 2005
Link: https://doi.org/10.1016/..
 
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13

Crystal Structures of Staphylococcus aureus Methionine Amin..:

Douangamath, Alice ; Dale, Glenn E. ; D'Arcy, Allan...
Journal of Medicinal Chemistry.  48 (2004)  1 - p. 336-336 , 2004
Link: https://doi.org/10.1021/..
 
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14

Modified microbatch and seeding in protein crystallization ..:

D'Arcy, Allan ; Mac Sweeney, Aengus ; Habera, Alexander
Journal of Synchrotron Radiation.  11 (2003)  1 - p. 24-26 , 2003
Link: https://doi.org/10.1107/..
 
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15

A simple and rapid method for mounting protein crystals at ..:

Mac Sweeney, Aengus ; D'Arcy, Allan
Journal of Applied Crystallography.  36 (2003)  1 - p. 165-166 , 2003
Link: https://doi.org/10.1107/..
 
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