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Mandy Lawson
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1

Metabolism-driven in vitro/in vivo disconnect of an oral ER..:

Hayhow, Thomas G. ; Williamson, Beth ; Lawson, Mandy...
Communications Biology.  7 (2024)  1 - p. , 2024
Link: https://doi.org/10.1038/..
 
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2

The Next-Generation Oral Selective Estrogen Receptor Degrad..:

Lawson, Mandy ; Cureton, Natalie ; Ros, Susana...
Cancer Research.  83 (2023)  23 - p. 3989-4004 , 2023
Link: https://doi.org/10.1158/..
 
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3

Discovery of a Potent and Orally Bioavailable Zwitterionic ..:

Scott, James S. ; Stead, Darren ; Barlaam, Bernard...
Journal of Medicinal Chemistry.  66 (2023)  4 - p. 2918-2945 , 2023
Link: https://doi.org/10.1021/..
 
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4

Genome engineering for estrogen receptor mutations reveals ..:

Harrod, Alison ; Lai, Chun-Fui ; Goldsbrough, Isabella...
Oncogene.  41 (2022)  44 - p. 4905-4915 , 2022
Link: https://doi.org/10.1038/..
 
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5

Discovery of AZD9833, a Potent and Orally Bioavailable Sele..:

Scott, James S. ; Moss, Thomas A. ; Balazs, Amber...
Journal of Medicinal Chemistry.  63 (2020)  23 - p. 14530-14559 , 2020
Link: https://doi.org/10.1021/..
 
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6

Tricyclic Indazoles—A Novel Class of Selective Estrogen Rec..:

Scott, James S. ; Bailey, Andrew ; Buttar, David...
Journal of Medicinal Chemistry.  62 (2019)  3 - p. 1593-1608 , 2019
Link: https://doi.org/10.1021/..
 
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7

Discovery of AZD3199, An Inhaled Ultralong Acting β2 Recept..:

Stocks, Michael J. ; Alcaraz, Lilian ; Bailey, Andrew...
ACS Medicinal Chemistry Letters.  5 (2014)  4 - p. 416-421 , 2014
Link: https://doi.org/10.1021/..
 
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8

From libraries to candidate: The discovery of new ultra lon..:

Alcaraz, Lilian ; Bailey, Andrew ; Cadogan, Elaine...
Bioorganic & Medicinal Chemistry Letters.  22 (2012)  1 - p. 689-695 , 2012
Link: https://doi.org/10.1016/..
 
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9

Design driven HtL: The discovery and synthesis of new high ..:

Stocks, Michael J. ; Alcaraz, Lilian ; Bailey, Andrew...
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  13 - p. 4027-4031 , 2011
Link: https://doi.org/10.1016/..
 
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10

Agonist‐specific patterns of β2‐adrenoceptor responses in h..:

Düringer, Caroline ; Grundström, Gunilla ; Gürcan, Eylem...
British Journal of Pharmacology.  158 (2009)  1 - p. 169-179 , 2009
Link: https://doi.org/10.1111/..
 
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11

Discovery of Potent and Selective Adamantane-Based Small-Mo..:

Furber, Mark ; Alcaraz, Lilian ; Bent, Janice E....
Journal of Medicinal Chemistry.  50 (2007)  24 - p. 5882-5885 , 2007
Link: https://doi.org/10.1021/..
 
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12

Reversible phosphatidylserine flip and interleukin-1β relea..:

Stevenson, Diane ; Lawson, Mandy ; Braddock, Martin..
Gastroenterology.  124 (2003)  4 - p. A156 , 2003
Link: https://doi.org/10.1016/..
 
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13

Hit-to-Lead studies: The discovery of potent adamantane ami..:

Baxter, Andrew ; Bent, Janice ; Bowers, Keith...
Bioorganic & Medicinal Chemistry Letters.  13 (2003)  22 - p. 4047-4050 , 2003
Link: https://doi.org/10.1016/..
 
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14

Expression and functions of purinergic receptor P2X7 in col..:

Li, Chris K.F. ; Bowers, Keith ; Pathamakanthan, Shri...
Gastroenterology.  120 (2001)  5 - p. A522 , 2001
Link: https://doi.org/10.1016/..
 
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15

Presence of the purinergic receptor P2X7 in colonic macroph..:

Li, Chris K. ; Bowers, Keith ; Pathmakanthan, Shri...
Gastroenterology.  118 (2000)  4 - p. A348 , 2000
Link: https://doi.org/10.1016/..
 
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