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Marcotte, Douglas J
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1

Discovery of Potent Isoindolinone Inhibitors that Target an..:

McCarthy, Kelly A. ; Marcotte, Douglas J. ; Parelkar, Sangram...
ChemMedChem.  19 (2024)  11 - p. , 2024
Link: https://doi.org/10.1002/..
 
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2

Elucidation of the GSK3α Structure Informs the Design of No..:

Amaral, Brenda ; Capacci, Andrew ; Anderson, Trip...
ACS Chemical Neuroscience.  14 (2023)  6 - p. 1080-1094 , 2023
Link: https://doi.org/10.1021/..
 
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3

Discovery of structural diverse reversible BTK inhibitors u..:

Vandeveer, George H. ; Arduini, Robert M. ; Baker, Darren P....
Bioorganic & Medicinal Chemistry Letters.  80 (2023)  - p. 129108 , 2023
Link: https://doi.org/10.1016/..
 
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4

Utilizing structure based drug design and metabolic soft sp..:

Hopkins, Brian T. ; Bame, Eris ; Bell, Noah...
Bioorganic & Medicinal Chemistry.  44 (2021)  - p. 116275 , 2021
Link: https://doi.org/10.1016/..
 
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5

Discovery of Potent, Selective, and Brain-Penetrant Apoptos..:

Jones, J. Howard ; Xin, Zhili ; Himmelbauer, Martin...
Journal of Medicinal Chemistry.  64 (2021)  20 - p. 15402-15419 , 2021
Link: https://doi.org/10.1021/..
 
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6

Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase ..:

Halkina, Tamara ; Henderson, Jaclyn L. ; Lin, Edward Y....
Journal of Medicinal Chemistry.  64 (2021)  9 - p. 6358-6380 , 2021
Link: https://doi.org/10.1021/..
 
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7

Discovery of Potent Selective Nonzinc Binding Autotaxin Inh..:

Ma, Bin ; Zhang, Lei ; Sun, Lihong...
ACS Medicinal Chemistry Letters.  12 (2021)  7 - p. 1124-1129 , 2021
Link: https://doi.org/10.1021/..
 
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8

Design, synthesis and identification of novel, orally bioav..:

Ma, Bin ; Lucas, Brian ; Capacci, Andrew...
Bioorganic & Medicinal Chemistry Letters.  30 (2020)  4 - p. 126852 , 2020
Link: https://doi.org/10.1016/..
 
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9

Mechanisms of Regulation and Diverse Activities of Tau-Tubu..:

Bao, Channa ; Bajrami, Bekim ; Marcotte, Douglas J....
Cellular and Molecular Neurobiology.  41 (2020)  4 - p. 669-685 , 2020
Link: https://doi.org/10.1007/..
 
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10

Discovery of BIIB068: A Selective, Potent, Reversible Bruto..:

Ma, Bin ; Bohnert, Tonika ; Otipoby, Kevin L....
Journal of Medicinal Chemistry.  63 (2020)  21 - p. 12526-12541 , 2020
Link: https://doi.org/10.1021/..
 
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11

Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kina..:

Xin, Zhili ; Himmelbauer, Martin K. ; Jones, J. Howard...
ACS Medicinal Chemistry Letters.  11 (2020)  4 - p. 485-490 , 2020
Link: https://doi.org/10.1021/..
 
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12

The crystal structure of the catalytic domain of tau tubuli..:

Marcotte, Douglas J. ; Spilker, Kerri A. ; Wen, Dingyi...
Acta Crystallographica Section F Structural Biology Communications.  76 (2020)  3 - p. 103-108 , 2020
Link: https://doi.org/10.1107/..
 
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13

Optimization of novel reversible Bruton's tyrosine kinase i..:

Hopkins, Brian T. ; Bame, Eris ; Bell, Noah...
Bioorganic & Medicinal Chemistry.  27 (2019)  13 - p. 2905-2913 , 2019
Link: https://doi.org/10.1016/..
 
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14

Rational Design and Optimization of a Novel Class of Macroc..:

Himmelbauer, Martin K. ; Xin, Zhili ; Jones, J. Howard...
Journal of Medicinal Chemistry.  62 (2019)  23 - p. 10740-10756 , 2019
Link: https://doi.org/10.1021/..
 
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15

Investigating small molecules to inhibit germinal center ki..:

May-Dracka, Tricia L. ; Arduini, Robert ; Bertolotti-Ciarlet, Andrea...
Bioorganic & Medicinal Chemistry Letters.  28 (2018)  10 - p. 1964-1971 , 2018
Link: https://doi.org/10.1016/..
 
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