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Martínez-Botella, Gabriel
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1

Discovery of the First Orally Available, Selective KNa1.1 I..:

Griffin, Andrew M. ; Kahlig, Kristopher M. ; Hatch, Robert John...
ACS Medicinal Chemistry Letters.  12 (2021)  4 - p. 593-602 , 2021
Link: https://doi.org/10.1021/..
 
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2

Discovery of VX-509 (Decernotinib): A Potent and Selective ..:

Farmer, Luc J. ; Ledeboer, Mark W. ; Hoock, Thomas...
Journal of Medicinal Chemistry.  58 (2015)  18 - p. 7195-7216 , 2015
Link: https://doi.org/10.1021/..
 
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3

Negishi cross-coupling enabled synthesis of novel NAD+-depe..:

Murphy-Benenato, Kerry E. ; Gingipalli, Lakshmaiah ; Boriack-Sjodin, P. Ann...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  22 - p. 5172-5177 , 2015
Link: https://doi.org/10.1016/..
 
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4

Antibacterial Inhibitors of Gram-Positive Thymidylate Kinas..:

Kawatkar, Sameer P. ; Keating, Thomas A. ; Olivier, Nelson B....
Journal of Medicinal Chemistry.  57 (2014)  11 - p. 4584-4597 , 2014
Link: https://doi.org/10.1021/..
 
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5

Structural Basis for Isoform Selectivity in a Class of Benz..:

Collier, Philip N. ; Martinez-Botella, Gabriel ; Cornebise, Mark...
Journal of Medicinal Chemistry.  58 (2014)  1 - p. 517-521 , 2014
Link: https://doi.org/10.1021/..
 
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6

Sulfonylpiperidines as novel, antibacterial inhibitors of G..:

Martínez-Botella, Gabriel ; Loch, James T. ; Green, Oluyinka M....
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  1 - p. 169-173 , 2013
Link: https://doi.org/10.1016/..
 
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7

In Vivo Validation of Thymidylate Kinase (TMK) with a Ratio..:

Keating, Thomas A. ; Newman, Joseph V. ; Olivier, Nelson B....
ACS Chemical Biology.  7 (2012)  11 - p. 1866-1872 , 2012
Link: https://doi.org/10.1021/..
 
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8

Discovery of Selective and Potent Inhibitors of Gram-Positi..:

Martínez-Botella, Gabriel ; Breen, John N. ; Duffy, James E. S....
Journal of Medicinal Chemistry.  55 (2012)  22 - p. 10010-10021 , 2012
Link: https://doi.org/10.1021/..
 
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9

Structure-Guided Design of Potent and Selective Pyrimidylpy..:

Aronov, Alex M. ; Tang, Qing ; Martinez-Botella, Gabriel...
Journal of Medicinal Chemistry.  52 (2009)  20 - p. 6362-6368 , 2009
Link: https://doi.org/10.1021/..
 
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10

Flipped Out:  Structure-Guided Design of Selective Pyrazoly..:

Aronov, Alex M. ; Baker, Christopher ; Bemis, Guy W....
Journal of Medicinal Chemistry.  50 (2007)  6 - p. 1280-1287 , 2007
Link: https://doi.org/10.1021/..
 
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11

The novel persistent sodium current inhibitor PRAX‐562 has ..:

Kahlig, Kristopher M. ; Scott, Liam ; Hatch, Robert J....
Epilepsia.  63 (2022)  3 - p. 697-708 , 2022
Link: https://doi.org/10.1111/..
 
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12

Discovery of the First Orally Available, Selective K(Na)1.1..:

Griffin, Andrew M ; Kahlig, Kristopher M ; Hatch, Robert John...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040054/.  , 2021
Link: http://www.ncbi.nlm.nih...
 
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13

Neuroactive Steroid N-Methyl-d-aspartate Receptor Positive ..:

La, Daniel S. ; Salituro, Francesco G. ; Martinez Botella, Gabriel...
Journal of Medicinal Chemistry.  62 (2019)  16 - p. 7526-7542 , 2019
Link: https://doi.org/10.1021/..
 
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14

Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1..:

Martinez Botella, Gabriel ; Salituro, Francesco G. ; Harrison, Boyd L....
Journal of Medicinal Chemistry.  60 (2017)  18 - p. 7810-7819 , 2017
Link: https://doi.org/10.1021/..
 
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15

Anticonvulsant profile of the neuroactive steroid, SGE-516,..:

Hammond, Rebecca S. ; Althaus, Alison L. ; Ackley, Michael A....
Epilepsy Research.  134 (2017)  - p. 16-25 , 2017
Link: https://doi.org/10.1016/..
 
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