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McKenzie, Grahame J
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1

Reporter cell lines to screen for inhibitors or regulators ..:

Weatherdon, Laura ; Stuart, Kate ; Cassidy, Megan...
Biochemical Journal.  481 (2024)  6 - p. 405-422 , 2024
Link: https://doi.org/10.1042/..
 
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2

A small-molecule inhibitor of the BRCA2-RAD51 interaction m..:

Scott, Duncan E. ; Francis-Newton, Nicola J. ; Marsh, May E....
Cell Chemical Biology.  28 (2021)  6 - p. 835-847.e5 , 2021
Link: https://doi.org/10.1016/..
 
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3

Target identification for small-molecule discovery in the F..:

Emery, Amy ; Hardwick, Bryn S. ; Crooks, Alex T....
Cell Chemical Biology.  28 (2021)  11 - p. 1602-1615.e9 , 2021
Link: https://doi.org/10.1016/..
 
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4

The pharmaceutical solvent N-methyl-2-pyrollidone (NMP) att..:

Roche-Molina, Marta ; Hardwick, Bryn ; Sanchez-Ramos, Cristina...
Scientific Reports.  10 (2020)  1 - p. , 2020
Link: https://doi.org/10.1038/..
 
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5

A cryptic hydrophobic pocket in the polo-box domain of the ..:

Sharma, Pooja ; Mahen, Robert ; Rossmann, Maxim...
Scientific Reports.  9 (2019)  1 - p. , 2019
Link: https://doi.org/10.1038/..
 
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6

Computationally-guided optimization of small-molecule inhib..:

Cole, Daniel J. ; Janecek, Matej ; Stokes, Jamie E....
Chemical Communications.  53 (2017)  67 - p. 9372-9375 , 2017
Link: https://doi.org/10.1039/..
 
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7

Modulating Protein-Protein Interactions of the Mitotic Polo..:

Narvaez, Ana J. ; Ber, Suzan ; Crooks, Alex...
Cell Chemical Biology.  24 (2017)  8 - p. 1017-1028.e7 , 2017
Link: https://doi.org/10.1016/..
 
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8

Allosteric modulation of AURKA kinase activity by a small-m..:

Janeček, Matej ; Rossmann, Maxim ; Sharma, Pooja...
Scientific Reports.  6 (2016)  1 - p. , 2016
Link: https://doi.org/10.1038/..
 
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9

Overcoming Chemical, Biological, and Computational Challeng..:

Laraia, Luca ; McKenzie, Grahame ; Spring, David R...
Chemistry & Biology.  22 (2015)  6 - p. 689-703 , 2015
Link: https://doi.org/10.1016/..
 
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10

Double Strain‐Promoted Macrocyclization for the Rapid Selec..:

Lau, Yu Heng ; Wu, Yuteng ; Rossmann, Maxim...
Angewandte Chemie International Edition.  54 (2015)  51 - p. 15410-15413 , 2015
Link: https://doi.org/10.1002/..
 
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11

LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldo..:

Shaikh, Lalarukh Haris ; Zhou, Junhua ; Teo, Ada E. D....
The Journal of Clinical Endocrinology & Metabolism.  100 (2015)  6 - p. E836-E844 , 2015
Link: https://doi.org/10.1210/..
 
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12

Double Strain-Promoted Macrocyclization for the Rapid Selec..:

Lau, Yu Heng ; Wu, Yuteng ; Rossmann, Maxim...
Angewandte Chemie.  127 (2015)  51 - p. 15630-15633 , 2015
Link: https://doi.org/10.1002/..
 
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13

Investigating peptide sequence variations for 'double-click..:

Lau, Yu Heng ; de Andrade, Peterson ; Sköld, Niklas...
Org. Biomol. Chem..  12 (2014)  24 - p. 4074-4077 , 2014
Link: https://doi.org/10.1039/..
 
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14

High Content Screening of Diverse Compound Libraries Identi..:

Laraia, Luca ; Stokes, Jamie ; Emery, Amy...
ACS Medicinal Chemistry Letters.  5 (2014)  5 - p. 598-603 , 2014
Link: https://doi.org/10.1021/..
 
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15

Linear Aliphatic Dialkynes as Alternative Linkers for Doubl..:

Lau, Yu Heng ; de Andrade, Peterson ; McKenzie, Grahame J...
ChemBioChem.  15 (2014)  18 - p. 2680-2683 , 2014
Link: https://doi.org/10.1002/..
 
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