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McKerrecher, Darren
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1

Potent and Selective Inhibitors of the Epidermal Growth Fac..:

Finlay, M. Raymond V. ; Barton, Peter ; Bickerton, Sue...
Journal of Medicinal Chemistry.  64 (2021)  18 - p. 13704-13718 , 2021
Link: https://doi.org/10.1021/..
 
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2

Challenges and Opportunities in Cancer Drug Resistance:

Ward, Richard A. ; Fawell, Stephen ; Floc'h, Nicolas...
Chemical Reviews.  121 (2020)  6 - p. 3297-3351 , 2020
Link: https://doi.org/10.1021/..
 
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3

Intramolecular Ring-Opening of Oxetanes: Access to Function..:

Bagal, Sharan K. ; Bodnarchuk, Michael S. ; King, Thomas A....
Synlett.  31 (2020)  5 - p. 502-506 , 2020
Link: https://doi.org/10.1055/..
 
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4

Circumventing Seizure Activity in a Series of G Protein Cou..:

Scott, James S. ; Bowker, Suzanne S. ; Brocklehurst, Katy J....
Journal of Medicinal Chemistry.  57 (2014)  21 - p. 8984-8998 , 2014
Link: https://doi.org/10.1021/..
 
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5

Optimisation of aqueous solubility in a series of G protein..:

Scott, James S. ; Birch, Alan M. ; Brocklehurst, Katy J....
MedChemComm.  4 (2013)  1 - p. 95-100 , 2013
Link: https://doi.org/10.1039/..
 
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6

Conformational restriction in a series of GPR119 agonists: ..:

Scott, James S. ; Brocklehurst, Katy J. ; Brown, Hayley S....
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  11 - p. 3175-3179 , 2013
Link: https://doi.org/10.1016/..
 
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7

A chemistry wiki to facilitate and enhance compound design ..:

Robb, Graeme R. ; McKerrecher, Darren ; Newcombe, Nicholas J..
Drug Discovery Today.  18 (2013)  3-4 - p. 141-147 , 2013
Link: https://doi.org/10.1016/..
 
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8

Use of Small-Molecule Crystal Structures To Address Solubil..:

Scott, James S. ; Birch, Alan M. ; Brocklehurst, Katy J....
Journal of Medicinal Chemistry.  55 (2012)  11 - p. 5361-5379 , 2012
Link: https://doi.org/10.1021/..
 
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9

Property based optimisation of glucokinase activators – dis..:

Waring, Michael J. ; Clarke, David S. ; Fenwick, Mark D....
MedChemComm.  3 (2012)  9 - p. 1077 , 2012
Link: https://doi.org/10.1039/..
 
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10

Overcoming retinoic acid receptor-α based testicular toxici..:

Waring, Michael J. ; Brogan, Iain J. ; Coghlan, Matthew...
MedChemComm.  2 (2011)  8 - p. 771 , 2011
Link: https://doi.org/10.1039/..
 
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11

Discovery, optimisation and in vivo evaluation of novel GPR..:

Brocklehurst, Katy J. ; Broo, Anders ; Butlin, Roger J....
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  24 - p. 7310-7316 , 2011
Link: https://doi.org/10.1016/..
 
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12

Matrix-based multiparameter optimisation of glucokinase act..:

Waring, Michael J. ; Johnstone, Craig ; McKerrecher, Darren..
MedChemComm.  2 (2011)  8 - p. 775 , 2011
Link: https://doi.org/10.1039/..
 
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13

Design of a potent, soluble glucokinase activator with incr..:

Pike, Kurt G. ; Allen, Joanne V. ; Caulkett, Peter W.R....
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  11 - p. 3467-3470 , 2011
Link: https://doi.org/10.1016/..
 
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14

Design of a potent, soluble glucokinase activator with exce..:

McKerrecher, Darren ; Allen, Joanne V. ; Caulkett, Peter W.R....
Bioorganic & Medicinal Chemistry Letters.  16 (2006)  10 - p. 2705-2709 , 2006
Link: https://doi.org/10.1016/..
 
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15

Discovery, synthesis and biological evaluation of novel glu..:

McKerrecher, Darren ; Allen, Joanne V. ; Bowker, Suzanne S....
Bioorganic & Medicinal Chemistry Letters.  15 (2005)  8 - p. 2103-2106 , 2005
Link: https://doi.org/10.1016/..
 
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