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Merritt, Hanne
28  results:
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1

Small molecule inhibition of glycogen synthase 1 restores a..:

Ullman, Julie C. ; Xi, Yannan ; Mellem, Kevin T....
Molecular Genetics and Metabolism.  138 (2023)  2 - p. 107338 , 2023
Link: https://doi.org/10.1016/..
 
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2

The structural mechanism of human glycogen synthesis by the..:

Fastman, Nathan M. ; Liu, Yuxi ; Ramanan, Vyas...
Cell Reports.  40 (2022)  1 - p. 111041 , 2022
Link: https://doi.org/10.1016/..
 
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3

In-vitro characterization of MZE001, an orally active GYS1 ..:

Choy, Rebeca ; Reiton, Daniel ; Merritt, Hanne...
Molecular Genetics and Metabolism.  135 (2022)  2 - p. S32 , 2022
Link: https://doi.org/10.1016/..
 
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4

Substrate reduction therapy for Pompe disease: Small molecu..:

Ullman, Julie C. ; Mellem, Kevin T. ; Xi, Yannan...
Molecular Genetics and Metabolism.  135 (2022)  2 - p. S122 , 2022
Link: https://doi.org/10.1016/..
 
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5

Pharmacology of small molecule inhibitors of GYS1 in a mous..:

Xi, Yannan ; Satterfield, Terrence F. ; Choy, Rebeca...
Molecular Genetics and Metabolism.  135 (2022)  2 - p. S128 , 2022
Link: https://doi.org/10.1016/..
 
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6

Two Distinct Mechanisms of Inhibition of LpxA Acyltransfera..:

Han, Wooseok ; Ma, Xiaolei ; Balibar, Carl J....
Journal of the American Chemical Society.  142 (2020)  9 - p. 4445-4455 , 2020
Link: https://doi.org/10.1021/..
 
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7

Design and Discovery of N-(3-(2-(2-Hydroxyethoxy)-6-morphol..:

Ramurthy, Savithri ; Taft, Benjamin R. ; Aversa, Robert J....
Journal of Medicinal Chemistry.  63 (2019)  5 - p. 2013-2027 , 2019
Link: https://doi.org/10.1021/..
 
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8

Imidazo[1,2- a ]pyridin-6-yl-benzamide analogs as potent RA..:

Smith, Aaron ; Ni, Zhi-Jie ; Poon, Daniel...
Bioorganic & Medicinal Chemistry Letters.  27 (2017)  23 - p. 5221-5224 , 2017
Link: https://doi.org/10.1016/..
 
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9

Design and Discovery of N-(2-Methyl-5′-morpholino-6′-((tetr..:

Nishiguchi, Gisele A. ; Rico, Alice ; Tanner, Huw...
Journal of Medicinal Chemistry.  60 (2017)  12 - p. 4869-4881 , 2017
Link: https://doi.org/10.1021/..
 
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10

Discovery of imidazo[1,2- a ]-pyridine inhibitors of pan-PI..:

Han, Wooseok ; Menezes, Daniel L. ; Xu, Yongjin...
Bioorganic & Medicinal Chemistry Letters.  26 (2016)  3 - p. 742-746 , 2016
Link: https://doi.org/10.1016/..
 
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11

Expression, purification and characterization of inactive a..:

Yan, Kelly ; Merritt, Hanne ; Crawford, Kenneth...
Protein Expression and Purification.  110 (2015)  - p. 172-179 , 2015
Link: https://doi.org/10.1016/..
 
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12

Structure guided optimization of a fragment hit to imidazop..:

Pecchi, Sabina ; Ni, Zhi-Jie ; Han, Wooseok...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  16 - p. 4652-4656 , 2013
Link: https://doi.org/10.1016/..
 
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13

Identification of NVP-BKM120 as a Potent, Selective, Orally..:

Burger, Matthew T. ; Pecchi, Sabina ; Wagman, Allan...
ACS Medicinal Chemistry Letters.  2 (2011)  10 - p. 774-779 , 2011
Link: https://doi.org/10.1021/..
 
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14

Identification and structure–activity relationship of 2-mor..:

Pecchi, Sabina ; Renhowe, Paul A. ; Taylor, Clarke...
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  23 - p. 6895-6898 , 2010
Link: https://doi.org/10.1016/..
 
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15

Internal AU‐rich elements modulate activity of two competin..:

Merritt, Hanne ; McCullough, Andrew J. ; Schuler, Mary A.
The Plant Journal.  12 (1997)  4 - p. 937-943 , 1997
Link: https://doi.org/10.1046/..
 
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