E-LIB Suche - Ergebnisse für: Murray, Brion W.

1

TPX-0131, a Potent CNS-penetrant, Next-generation Inhibitor..:

Murray, Brion W. ; Zhai, Dayong ; Deng, Wei...
Molecular Cancer Therapeutics. 20 (2021) 9 - p. 1499-1507 , 2021

2

Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Trea..:

Freeman-Cook, Kevin D. ; Hoffman, Robert L. ; Behenna, Douglas C....
Journal of Medicinal Chemistry. 64 (2021) 13 - p. 9056-9077 , 2021

Link: https://doi.org/10.1021/..

3

Molecular Characteristics of Repotrectinib That Enable Pote..:

Murray, Brion W. ; Rogers, Evan ; Zhai, Dayong...
Molecular Cancer Therapeutics. 20 (2021) 12 - p. 2446-2456 , 2021

Link: https://doi.org/10.1158/..

4

Symmetric Arginine Dimethylation Is Selectively Required fo..:

Metz, Patrick J. ; Ching, Keith A. ; Xie, Tao...
Cell Reports. 30 (2020) 6 - p. 1935-1950.e8 , 2020

Link: https://doi.org/10.1016/..

5

Discovery of Ketone-Based Covalent Inhibitors of Coronaviru..:

Hoffman, Robert L. ; Kania, Robert S. ; Brothers, Mary A....
Journal of Medicinal Chemistry. 63 (2020) 21 - p. 12725-12747 , 2020

Link: https://doi.org/10.1021/..

6

Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-..:

Planken, Simon ; Behenna, Douglas C. ; Nair, Sajiv K....
Journal of Medicinal Chemistry. 60 (2017) 7 - p. 3002-3019 , 2017

Link: https://doi.org/10.1021/..

7

The Axl kinase domain in complex with a macrocyclic inhibit..:

Gajiwala, Ketan S. ; Grodsky, Neil ; Bolaños, Ben...
Journal of Biological Chemistry. 292 (2017) 38 - p. 15705-15716 , 2017

Link: https://doi.org/10.1074/..

8

Discovery of a Novel and Selective Indoleamine 2,3-Dioxygen..:

Crosignani, Stefano ; Bingham, Patrick ; Bottemanne, Pauline...
Journal of Medicinal Chemistry. 60 (2017) 23 - p. 9617-9629 , 2017

Link: https://doi.org/10.1021/..

9

Genomic profiling and treatment of HER2+, ER+, PgR+ "triple..:

Schwab, Richard B. ; Koehler, Maria ; Ali, Siraj M..
Cancer Treatment and Research Communications. 9 (2016) - p. 27-31 , 2016

Link: https://doi.org/10.1016/..

10

Recent progress on third generation covalent EGFR inhibitor:

Cheng, Hengmiao ; Nair, Sajiv K. ; Murray, Brion W.
Bioorganic & Medicinal Chemistry Letters. 26 (2016) 8 - p. 1861-1868 , 2016

Link: https://doi.org/10.1016/..

11

Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyraz..:

Cheng, Hengmiao ; Nair, Sajiv K. ; Murray, Brion W....
Journal of Medicinal Chemistry. 59 (2016) 5 - p. 2005-2024 , 2016

Link: https://doi.org/10.1021/..

12

Axitinib effectively inhibits BCR-ABL1(T315I) with a distin..:

Pemovska, Tea ; Johnson, Eric ; Kontro, Mika...
Nature. 519 (2015) 7541 - p. 102-105 , 2015

Link: https://doi.org/10.1038/..

13

An algebraic model for the kinetics of covalent enzyme inhi..:

Kuzmič, Petr ; Solowiej, James ; Murray, Brion W.
Analytical Biochemistry. 484 (2015) - p. 82-90 , 2015

Link: https://doi.org/10.1016/..

14

Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiol..:

Martinez, Ricardo ; Blasina, Alessandra ; Hallin, Jill F....
PLOS ONE. 10 (2015) 9 - p. e0138616 , 2015

Link: https://doi.org/10.1371/..

15

Protein redox chemistry: post-translational cysteine modifi..:

Wani, Revati ; Nagata, Asako ; Murray, Brion W.
Frontiers in Pharmacology. 5 (2014) - p. , 2014

Link: https://doi.org/10.3389/..