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Myöhänen, Timo T.
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1

5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl..:

Pätsi, Henri T. ; Kilpeläinen, Tommi P. ; Jumppanen, Mikael...
Journal of Medicinal Chemistry.  67 (2024)  7 - p. 5421-5436 , 2024
Link: https://doi.org/10.1021/..
 
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2

Novel Small‐Molecular Ligands for Prolyl Oligopeptidase to ..:

Eteläinen, Tony ; Pätsi, Henri ; Uhari‐Väänänen, Johanna...
Alzheimer's & Dementia.  19 (2023)  S21 - p. , 2023
Link: https://doi.org/10.1002/..
 
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3

Nigrostriatal 6-hydroxydopamine lesions increase alpha-synu..:

Cui, Hengjing ; Elford, Joshua D. ; Alitalo, Okko...
Neurobiology of Aging.  129 (2023)  - p. 62-71 , 2023
Link: https://doi.org/10.1016/..
 
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4

Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands wit..:

Kilpeläinen, Tommi P. ; Pätsi, Henri T. ; Svarcbahs, Reinis...
Journal of Medicinal Chemistry.  66 (2023)  11 - p. 7475-7496 , 2023
Link: https://doi.org/10.1021/..
 
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5

Removal of proteinase K resistant αSyn species does not cor..:

Eteläinen, Tony S. ; Kilpeläinen, Tommi P. ; Ignatius, Adele...
Neuropharmacology.  218 (2022)  - p. 109213 , 2022
Link: https://doi.org/10.1016/..
 
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6

Prolyl oligopeptidase inhibition reduces alpha‐synuclein ag..:

Cui, Hengjing ; Kilpeläinen, Tommi ; Zouzoula, Lydia...
Journal of Cellular and Molecular Medicine.  25 (2021)  20 - p. 9634-9646 , 2021
Link: https://doi.org/10.1111/..
 
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7

Deletion or inhibition of prolyl oligopeptidase blocks lith..:

Myöhänen, Timo T. ; Mertens, Freke ; Norrbacka, Susanna.
Basic & Clinical Pharmacology & Toxicology.  129 (2021)  4 - p. 287-296 , 2021
Link: https://doi.org/10.1111/..
 
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8

Prolyl Oligopeptidase Regulates Dopamine Transporter Oligom..:

Julku, Ulrika H. ; Jäntti, Maria ; Svarcbahs, Reinis.
International Journal of Molecular Sciences.  22 (2021)  4 - p. 1777 , 2021
Link: https://doi.org/10.3390/..
 
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9

2-Imidazole as a Substitute for the Electrophilic Group Giv..:

Pätsi, Henri T. ; Kilpeläinen, Tommi P. ; Auno, Samuli...
ACS Medicinal Chemistry Letters.  12 (2021)  10 - p. 1578-1584 , 2021
Link: https://doi.org/10.1021/..
 
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10

Prolyl oligopeptidase inhibition activates autophagy via pr..:

Svarcbahs, Reinis ; Jäntti, Maria ; Kilpeläinen, Tommi...
Pharmacological Research.  151 (2020)  - p. 104558 , 2020
Link: https://doi.org/10.1016/..
 
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11

The effect of prolyl oligopeptidase inhibitors on alpha-syn..:

Kilpeläinen, Tommi P. ; Hellinen, Laura ; Vrijdag, Johannes...
Biomedicine & Pharmacotherapy.  128 (2020)  - p. 110253 , 2020
Link: https://doi.org/10.1016/..
 
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12

Prolyl oligopeptidase inhibition reduces PolyQ aggregation ..:

Norrbacka, Susanna ; Lindholm, Dan ; Myöhänen, Timo T.
Journal of Cellular and Molecular Medicine.  23 (2019)  12 - p. 8511-8515 , 2019
Link: https://doi.org/10.1111/..
 
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13

Behavioural and dopaminergic changes in double mutated huma..:

Kilpeläinen, Tommi ; Julku, Ulrika H. ; Svarcbahs, Reinis.
Scientific Reports.  9 (2019)  1 - p. , 2019
Link: https://doi.org/10.1038/..
 
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14

Tetrazole as a Replacement of the Electrophilic Group in Ch..:

Kilpeläinen, Tommi P. ; Tyni, Jonna K. ; Lahtela-Kakkonen, Maija K....
ACS Medicinal Chemistry Letters.  10 (2019)  12 - p. 1635-1640 , 2019
Link: https://doi.org/10.1021/..
 
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15

New tricks of prolyl oligopeptidase inhibitors – A common d..:

Svarcbahs, Reinis ; Julku, Ulrika ; Kilpeläinen, Tommi...
Biochemical Pharmacology.  161 (2019)  - p. 113-120 , 2019
Link: https://doi.org/10.1016/..
 
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