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Nigel Austin
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1

Discovery of OICR12694: A Novel, Potent, Selective, and Ora..:

Mamai, Ahmed ; Chau, Anh M. ; Wilson, Brian J....
ACS Medicinal Chemistry Letters.  14 (2023)  2 - p. 199-210 , 2023
Link: https://doi.org/10.1021/..
 
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2

Pharmacological modulation of TSPO in microglia/macrophages..:

Vicente-Rodríguez, Marta ; Mancuso, Renzo ; Peris-Yague, Alba...
Journal of Neuroinflammation.  20 (2023)  1 - p. , 2023
Link: https://doi.org/10.1186/..
 
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3

The Identification of GPR52 Agonist HTL0041178, a Potential..:

Poulter, Simon ; Austin, Nigel ; Armstrong, Rachel...
ACS Medicinal Chemistry Letters.  14 (2023)  4 - p. 499-505 , 2023
Link: https://doi.org/10.1021/..
 
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4

JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective B..:

Rombouts, Frederik J. R. ; Kusakabe, Ken-ichi ; Alexander, Richard...
Journal of Medicinal Chemistry.  64 (2021)  19 - p. 14175-14191 , 2021
Link: https://doi.org/10.1021/..
 
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5

A Modest Increase in 11C-PK11195-Positron Emission Tomograp..:

Schubert, Julia J. ; Veronese, Mattia ; Fryer, Tim D....
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.  6 (2021)  7 - p. 716-724 , 2021
Link: https://doi.org/10.1016/..
 
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6

A Brain-Penetrant and Bioavailable Pyrazolopiperazine BACE1..:

Peschiulli, Aldo ; Oehlrich, Daniel ; Van Gool, Michiel...
ACS Medicinal Chemistry Letters.  13 (2021)  1 - p. 76-83 , 2021
Link: https://doi.org/10.1021/..
 
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7

CSF1R inhibitor JNJ-40346527 attenuates microglial prolifer..:

Mancuso, Renzo ; Fryatt, Gemma ; Cleal, Madeleine...
Brain.  142 (2019)  10 - p. 3243-3264 , 2019
Link: https://doi.org/10.1093/..
 
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8

Discovery and optimization of a series of small-molecule al..:

Lu, Tianbao ; Connolly, Peter J. ; Philippar, Ulrike...
Bioorganic & Medicinal Chemistry Letters.  29 (2019)  23 - p. 126743 , 2019
Link: https://doi.org/10.1016/..
 
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9

Evaluation of a Series of β-Secretase 1 Inhibitors Containi..:

Oehlrich, Daniel ; Peschiulli, Aldo ; Tresadern, Gary...
ACS Medicinal Chemistry Letters.  10 (2019)  8 - p. 1159-1165 , 2019
Link: https://doi.org/10.1021/..
 
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10

Design and synthesis of a novel series of cyanoindole deriv..:

Bischoff, François P. ; Velter, Adriana Ingrid ; Minne, Garrett...
Bioorganic & Medicinal Chemistry Letters.  29 (2019)  14 - p. 1737-1745 , 2019
Link: https://doi.org/10.1016/..
 
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11

Trifluoromethyl Dihydrothiazine‐Based β‐Secretase (BACE1) I..:

Anan, Kosuke ; Iso, Yasuyoshi ; Oguma, Takuya...
ChemMedChem.  14 (2019)  22 - p. 1894-1910 , 2019
Link: https://doi.org/10.1002/..
 
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12

Discovery of an Extremely Potent Thiazine-Based β-Secretase..:

Tadano, Genta ; Komano, Kazuo ; Yoshida, Shuhei...
Journal of Medicinal Chemistry.  62 (2019)  20 - p. 9331-9337 , 2019
Link: https://doi.org/10.1021/..
 
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13

Correction to Optimization of 1,4-Oxazine β-Secretase 1 (BA..:

Gijsen, Harrie J. M. ; Alonso de Diego, Sergio A. ; De Cleyn, Michel...
Journal of Medicinal Chemistry.  61 (2018)  24 - p. 11415-11415 , 2018
Link: https://doi.org/10.1021/..
 
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14

Optimization of 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitor..:

Gijsen, Harrie J. M. ; Alonso de Diego, Sergio A. ; De Cleyn, Michel...
Journal of Medicinal Chemistry.  61 (2018)  12 - p. 5292-5303 , 2018
Link: https://doi.org/10.1021/..
 
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15

Discovery of N-(Pyridin-4-yl)-1,5-naphthyridin-2-amines as ..:

Rombouts, Frederik J. R. ; Andrés, José-Ignacio ; Ariza, Manuela...
Journal of Medicinal Chemistry.  60 (2017)  4 - p. 1272-1291 , 2017
Link: https://doi.org/10.1021/..
 
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