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Owen, Dafydd R.
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1

Discovery of PFI-6, a small-molecule chemical probe for the..:

Raux, Brigitt ; Buchan, Karly A. ; Bennett, James...
Bioorganic & Medicinal Chemistry Letters.  98 (2024)  - p. 129546 , 2024
Link: https://doi.org/10.1016/..
 
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2

A chemical probe to modulate human GID4 Pro/N-degron intera..:

Owens, Dominic D. G. ; Maitland, Matthew E. R. ; Khalili Yazdi, Aliakbar...
Nature Chemical Biology.  , 2024
Link: https://doi.org/10.1038/..
 
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3

A data science roadmap for open science organizations engag..:

Edfeldt, Kristina ; Edwards, Aled M. ; Engkvist, Ola...
Nature Communications.  15 (2024)  1 - p. , 2024
Link: https://doi.org/10.1038/..
 
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4

Chemical tools for the Gid4 subunit of the human E3 ligase ..:

Yazdi, Aliakbar Khalili ; Perveen, Sumera ; Dong, Cheng...
RSC Medicinal Chemistry.  15 (2024)  3 - p. 1066-1071 , 2024
Link: https://doi.org/10.1039/..
 
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5

Discovery of High-Affinity Small-Molecule Binders of the Ep..:

Londregan, Allyn T. ; Aitmakhanova, Karlygash ; Bennett, James...
Journal of Medicinal Chemistry.  66 (2022)  1 - p. 460-472 , 2022
Link: https://doi.org/10.1021/..
 
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6

An oral SARS-CoV-2 Mproinhibitor clinical candidate for the..:

Owen, Dafydd R. ; Allerton, Charlotte M. N. ; Anderson, Annaliesa S....
Science.  374 (2021)  6575 - p. 1586-1593 , 2021
Link: https://doi.org/10.1126/..
 
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7

Structure and Inhibitor Binding Characterization of Oncogen..:

Ni, Xiaomin ; Londregan, Allyn T. ; Owen, Dafydd R...
ACS Chemical Biology.  16 (2021)  4 - p. 571-578 , 2021
Link: https://doi.org/10.1021/..
 
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8

Investigating 3,3-diaryloxetanes as potential bioisosteres ..:

Dubois, Maryne A. J. ; Croft, Rosemary A. ; Ding, Yujie...
RSC Medicinal Chemistry.  12 (2021)  12 - p. 2045-2052 , 2021
Link: https://doi.org/10.1039/..
 
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9

Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-0682664..:

Gerstenberger, Brian S. ; Ambler, Catherine ; Arnold, Eric P....
Journal of Medicinal Chemistry.  63 (2020)  22 - p. 13561-13577 , 2020
Link: https://doi.org/10.1021/..
 
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10

Selective, Small-Molecule Co-Factor Binding Site Inhibition..:

Taylor, Alexandria P. ; Swewczyk, Magdalena ; Kennedy, Steven...
Journal of Medicinal Chemistry.  62 (2019)  17 - p. 7669-7683 , 2019
Link: https://doi.org/10.1021/..
 
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11

Design and identification of a novel, functionally subtype ..:

Owen, Robert M. ; Blakemore, David C ; Cao, Lishuang...
Journal of Medicinal Chemistry.  , 2019
Link: https://doi.org/10.1021/..
 
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12

Design of a Biased Potent Small Molecule Inhibitor of the B..:

Igoe, Niall ; Bayle, Elliott D. ; Fedorov, Oleg...
Journal of Medicinal Chemistry.  60 (2017)  2 - p. 668-680 , 2017
Link: https://doi.org/10.1021/..
 
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13

Selective Targeting of Bromodomains of the Bromodomain-PHD ..:

Meier, Julia C. ; Tallant, Cynthia ; Fedorov, Oleg...
ACS Chemical Biology.  12 (2017)  10 - p. 2619-2630 , 2017
Link: https://doi.org/10.1021/..
 
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14

Identification of a Chemical Probe for Family VIII Bromodom..:

Gerstenberger, Brian S. ; Trzupek, John D. ; Tallant, Cynthia...
Journal of Medicinal Chemistry.  59 (2016)  10 - p. 4800-4811 , 2016
Link: https://doi.org/10.1021/..
 
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15

Lysine Methyltransferase SETD7 (SET7/9) Regulates ROS Signa..:

He, Shuying ; Owen, Dafydd R. ; Jelinsky, Scott A..
Scientific Reports.  5 (2015)  1 - p. , 2015
Link: https://doi.org/10.1038/..
 
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