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Pablo David Grigol Martinez
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1

Hit-to-lead optimization of a 2-aminobenzimidazole series a..:

de Oliveira Rezende Júnior, Celso ; Martinez, Pablo David Grigol ; Ferreira, Rafael Augusto Alves...
European Journal of Medicinal Chemistry.  246 (2023)  - p. 114925 , 2023
Link: https://doi.org/10.1016/..
 
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2

2-aminobenzimidazoles for leishmaniasis: From initial hit d..:

Ferreira, Rafael Augusto Alves ; Junior, Celso de Oliveira Rezende ; Martinez, Pablo David Grigol...
PLOS Neglected Tropical Diseases.  15 (2021)  2 - p. e0009196 , 2021
Link: https://doi.org/10.1371/..
 
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3

2-aminobenzimidazoles for leishmaniasis: From initial hit d..:

Rafael Augusto Alves Ferreira ; Celso de Oliveira Rezende Junior ; Pablo David Grigol Martinez...
https://doi.org/10.1371/journal.pntd.0009196.  , 2021
Link: https://doi.org/10.1371/..
 
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4

In vitro profiling of analogues with modifications at the N..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_modifications_at_the_N-alkyl_chain_/14078740.  , 2021
Link: https://doi.org/10.1371/..
 
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5

Chemical structure, initial hit assessment data and metabol..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Chemical_structure_initial_hit_assessment_data_and_metabolic_soft_spots_for_compound_1_/14078728.  , 2021
Link: https://doi.org/10.1371/..
 
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6

Complete biological dataset:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/dataset/Complete_biological_dataset_/14078722.  , 2021
Link: https://doi.org/10.1371/..
 
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7

Proof of concept in vivo activity in a VL acute model:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Proof_of_concept_in_vivo_activity_in_a_VL_acute_model_/14078755.  , 2021
Link: https://doi.org/10.1371/..
 
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8

Synthesis of purine 56:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Synthesis_of_purine_56_/14078734.  , 2021
Link: https://doi.org/10.1371/..
 
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9

In vitro profiling of analogues with additional modificatio..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_additional_modifications_at_the_benzimidazole_core_and_side_chain_/14078746.  , 2021
Link: https://doi.org/10.1371/..
 
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10

Summary of SARs and SPRs for 2-aminobenzimidazole derivativ..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Summary_of_SARs_and_SPRs_for_2-aminobenzimidazole_derivatives_/14078752.  , 2021
Link: https://doi.org/10.1371/..
 
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11

Detailed synthetic and spectral information:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/journal_contribution/Detailed_synthetic_and_spectral_information_/14078725.  , 2021
Link: https://doi.org/10.1371/..
 
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12

In vitro profiling of analogues with modifications in the b..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_modifications_in_the_benzimidazole_ring_/14078737.  , 2021
Link: https://doi.org/10.1371/..
 
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13

In vitro profiling of analogues with modifications at the a..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_modifications_at_the_amide_group_/14078743.  , 2021
Link: https://doi.org/10.1371/..
 
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14

Summary of in vitro ADME and in vivo PK data for selected c..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/dataset/Summary_of_in_vitro_ADME_and_in_vivo_PK_data_for_selected_compounds_/14078758.  , 2021
Link: https://doi.org/10.1371/..
 
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15

Synthesis of 2-aminobenzimidazoles:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Synthesis_of_2-aminobenzimidazoles_/14078731.  , 2021
Link: https://doi.org/10.1371/..
 
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