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Pfefferkorn, Jeffrey A.
191  results:
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1

Discovery of Ervogastat (PF-06865571): A Potent and Selecti..:

Futatsugi, Kentaro ; Cabral, Shawn ; Kung, Daniel W....
Journal of Medicinal Chemistry.  65 (2022)  22 - p. 15000-15013 , 2022
Link: https://doi.org/10.1021/..
 
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2

Pharmacologic inhibition of ketohexokinase prevents fructos..:

Gutierrez, Jemy A. ; Liu, Wei ; Perez, Sylvie...
Molecular Metabolism.  48 (2021)  - p. 101196 , 2021
Link: https://doi.org/10.1016/..
 
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3

ACC inhibitor alone or co-administered with a DGAT2 inhibit..:

Calle, Roberto A. ; Amin, Neeta B. ; Carvajal-Gonzalez, Santos...
Nature Medicine.  27 (2021)  10 - p. 1836-1848 , 2021
Link: https://doi.org/10.1038/..
 
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4

Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhib..:

Huard, Kim ; Smith, Aaron C. ; Cappon, Gregg...
Journal of Medicinal Chemistry.  63 (2020)  19 - p. 10879-10896 , 2020
Link: https://doi.org/10.1021/..
 
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5

Quantitation of Urinary Acylcarnitines by DMS-MS/MS Uncover..:

Vera, Nicholas B. ; Coy, Stephen L. ; Laiakis, Evagelia C....
Journal of the American Society for Mass Spectrometry.  31 (2020)  3 - p. 498-507 , 2020
Link: https://doi.org/10.1021/..
 
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6

Discovery of PF-06835919: A Potent Inhibitor of Ketohexokin..:

Futatsugi, Kentaro ; Smith, Aaron C. ; Tu, Meihua...
Journal of Medicinal Chemistry.  63 (2020)  22 - p. 13546-13560 , 2020
Link: https://doi.org/10.1021/..
 
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7

Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensi..:

Ross, Trenton T. ; Crowley, Collin ; Kelly, Kenneth L....
Cellular and Molecular Gastroenterology and Hepatology.  10 (2020)  4 - p. 829-851 , 2020
Link: https://doi.org/10.1016/..
 
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8

Effect of Hepatic Organic Anion‐Transporting Polypeptide 1B..:

Bergman, Arthur ; Bi, Yi‐an ; Mathialagan, Sumathy...
Clinical Pharmacology & Therapeutics.  106 (2019)  4 - p. 792-802 , 2019
Link: https://doi.org/10.1002/..
 
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9

PS-132-The acetyl-CoA carboxylase inhibitor PF-05221304 exe..:

Ross, Trenton ; Kelly, Kenneth ; Rinaldi, Anthony...
Journal of Hepatology.  70 (2019)  1 - p. e86 , 2019
Link: https://doi.org/10.1016/..
 
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10

PS-109-Partial inhibition of de novo lipogenesis with the a..:

Esler, William ; Ross, Trenton ; Bergman, Arthur...
Journal of Hepatology.  70 (2019)  1 - p. e69 , 2019
Link: https://doi.org/10.1016/..
 
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11

Differential mobility spectrometry (DMS) reveals the elevat..:

Vera, Nicholas B. ; Chen, Zhidan ; Pannkuk, Evan...
Journal of Mass Spectrometry.  53 (2018)  7 - p. 548-559 , 2018
Link: https://doi.org/10.1002/..
 
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12

Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) ..:

Jones, Jessica E. C. ; Esler, William P. ; Patel, Rushi...
PLOS ONE.  12 (2017)  1 - p. e0169566 , 2017
Link: https://doi.org/10.1371/..
 
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13

Discovery of Fragment-Derived Small Molecules for in Vivo I..:

Huard, Kim ; Ahn, Kay ; Amor, Paul...
Journal of Medicinal Chemistry.  60 (2017)  18 - p. 7835-7849 , 2017
Link: https://doi.org/10.1021/..
 
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14

Discovery of a Selective Covalent Inhibitor of Lysophosphol..:

Ahn, Kay ; Boehm, Markus ; Brown, Matthew F....
ACS Chemical Biology.  11 (2016)  9 - p. 2529-2540 , 2016
Link: https://doi.org/10.1021/..
 
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15

Discovery and characterization of novel inhibitors of the s..:

Huard, Kim ; Brown, Janice ; Jones, Jessica C....
Scientific Reports.  5 (2015)  1 - p. , 2015
Link: https://doi.org/10.1038/..
 
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