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Pinto, Donald J.P.
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1

Discovery of Milvexian, a High-Affinity, Orally Bioavailabl..:

Dilger, Andrew K. ; Pabbisetty, Kumar B. ; Corte, James R....
Journal of Medicinal Chemistry.  65 (2021)  3 - p. 1770-1785 , 2021
Link: https://doi.org/10.1021/..
 
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2

Structure based design of macrocyclic factor XIa inhibitors..:

Clark, Charles G. ; Rossi, Karen A. ; Corte, James R....
Bioorganic & Medicinal Chemistry Letters.  29 (2019)  19 - p. 126604 , 2019
Link: https://doi.org/10.1016/..
 
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3

Potent, Orally Bioavailable, and Efficacious Macrocyclic In..:

Corte, James R. ; Pinto, Donald J. P. ; Fang, Tianan...
Journal of Medicinal Chemistry.  63 (2019)  2 - p. 784-803 , 2019
Link: https://doi.org/10.1021/..
 
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4

Factor XIa Inhibitors as New Anticoagulants:

Quan, Mimi L. ; Pinto, Donald J. P. ; Smallheer, Joanne M....
Journal of Medicinal Chemistry.  61 (2018)  17 - p. 7425-7447 , 2018
Link: https://doi.org/10.1021/..
 
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5

Structure-Based Design of Macrocyclic Factor XIa Inhibitors..:

Corte, James R. ; Fang, Tianan ; Osuna, Honey...
Journal of Medicinal Chemistry.  60 (2017)  3 - p. 1060-1075 , 2017
Link: https://doi.org/10.1021/..
 
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6

Discovery of a Parenteral Small Molecule Coagulation Factor..:

Pinto, Donald J. P. ; Orwat, Michael J. ; Smith II, Leon M....
Journal of Medicinal Chemistry.  60 (2017)  23 - p. 9703-9723 , 2017
Link: https://doi.org/10.1021/..
 
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7

Novel phenylalanine derived diamides as Factor XIa inhibito..:

Smith II, Leon M. ; Orwat, Michael J. ; Hu, Zilun...
Bioorganic & Medicinal Chemistry Letters.  26 (2016)  2 - p. 472-478 , 2016
Link: https://doi.org/10.1016/..
 
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8

Orally bioavailable pyridine and pyrimidine-based Factor XI..:

Corte, James R. ; Fang, Tianan ; Pinto, Donald J.P....
Bioorganic & Medicinal Chemistry.  24 (2016)  10 - p. 2257-2272 , 2016
Link: https://doi.org/10.1016/..
 
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9

Structure-based design of inhibitors of coagulation factor ..:

Pinto, Donald J.P. ; Smallheer, Joanne M. ; Corte, James R....
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  7 - p. 1635-1642 , 2015
Link: https://doi.org/10.1016/..
 
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10

Orally bioavailable factor Xa inhibitors containing alpha-s..:

Orwat, Michael J. ; Qiao, Jennifer X. ; He, Kan...
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  15 - p. 3341-3345 , 2014
Link: https://doi.org/10.1016/..
 
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11

Preclinical pharmacokinetics and pharmacodynamics of apixab..:

He, Kan ; Luettgen, Joseph M. ; Zhang, Donglu...
European Journal of Drug Metabolism and Pharmacokinetics.  36 (2011)  3 - p. 129-139 , 2011
Link: https://doi.org/10.1007/..
 
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12

Preclinical discovery of apixaban, a direct and orally bioa..:

Wong, Pancras C. ; Pinto, Donald J. P. ; Zhang, Donglu
Journal of Thrombosis and Thrombolysis.  31 (2011)  4 - p. 478-492 , 2011
Link: https://doi.org/10.1007/..
 
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13

Factor Xa Inhibitors: Next-Generation Antithrombotic Agents:

Pinto, Donald J. P. ; Smallheer, Joanne M. ; Cheney, Daniel L...
Journal of Medicinal Chemistry.  53 (2010)  17 - p. 6243-6274 , 2010
Link: https://doi.org/10.1021/..
 
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14

Phenyltriazolinones as potent factor Xa inhibitors:

Quan, Mimi L. ; Pinto, Donald J.P. ; Rossi, Karen A....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  4 - p. 1373-1377 , 2010
Link: https://doi.org/10.1016/..
 
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15

Structure–activity relationship and pharmacokinetic profile..:

Varnes, Jeffrey G. ; Wacker, Dean A. ; Pinto, Donald J.P....
Bioorganic & Medicinal Chemistry Letters.  18 (2008)  2 - p. 749-754 , 2008
Link: https://doi.org/10.1016/..
 
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