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Rueeger, Heinrich
24
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Online (24)
Mediatypes
Articles (Online) (17)
OpenAccess-fulltext (7)
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1
Identification of NVP-CLR457 as an Orally Bioavailable Non-..:
Fairhurst, Robin A.
;
Furet, Pascal
;
Imbach-Weese, Patricia
...
Journal of Medicinal Chemistry. 65 (2022) 12 - p. 8345-8379 , 2022
Link:
https://doi.org/10.1021/..
?
2
BET bromodomain inhibitors regulate keratinocyte plasticity:
Schutzius, Gabi
;
Kolter, Christian
;
Bergling, Sebastian
...
Nature Chemical Biology. 17 (2021) 3 - p. 280-290 , 2021
Link:
https://doi.org/10.1038/..
?
3
Discovery of Umibecestat (CNP520): A Potent, Selective, and..:
Machauer, Rainer
;
Lueoend, Rainer
;
Hurth, Konstanze
...
Journal of Medicinal Chemistry. 64 (2021) 20 - p. 15262-15279 , 2021
Link:
https://doi.org/10.1021/..
?
4
Synthesis of the Potent, Selective, and Efficacious β-Secre..:
Rueeger, Heinrich
;
Lueoend, Rainer
;
Machauer, Rainer
...
Journal of Medicinal Chemistry. 64 (2021) 8 - p. 4677-4696 , 2021
Link:
https://doi.org/10.1021/..
?
5
TheBACE‐1 inhibitorCNP520 for prevention trials in Alzheime..:
Neumann, Ulf
;
Ufer, Mike
;
Jacobson, Laura H
...
EMBO Molecular Medicine. 10 (2018) 11 - p. , 2018
Link:
https://doi.org/10.15252..
?
6
Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors:
Veenstra, Siem Jakob
;
Rueeger, Heinrich
;
Voegtle, Markus
...
Bioorganic & Medicinal Chemistry Letters. 28 (2018) 12 - p. 2195-2200 , 2018
Link:
https://doi.org/10.1016/..
?
7
A novel BACE inhibitor NB-360 shows a superior pharmacologi..:
Neumann, Ulf
;
Rueeger, Heinrich
;
Machauer, Rainer
...
Molecular Neurodegeneration. 10 (2015) 1 - p. , 2015
Link:
https://doi.org/10.1186/..
?
8
P4‐363: THE BACE INHIBITOR NB‐360 HAS EXCELLENT BRAIN PENET..:
Neumann, Ulf
;
Rueeger, Heinrich
;
Machauer, Rainer
...
Alzheimer's & Dementia. 10 (2014) 4S_Part_16 - p. , 2014
Link:
https://doi.org/10.1016/..
?
9
Discovery of cyclic sulfoxide hydroxyethylamines as potent ..:
Rueeger, Heinrich
;
Lueoend, Rainer
;
Machauer, Rainer
...
Bioorganic & Medicinal Chemistry Letters. 23 (2013) 19 - p. 5300-5306 , 2013
Link:
https://doi.org/10.1016/..
?
10
Discovery of Cyclic Sulfone Hydroxyethylamines as Potent an..:
Rueeger, Heinrich
;
Lueoend, Rainer
;
Rogel, Olivier
...
Journal of Medicinal Chemistry. 55 (2012) 7 - p. 3364-3386 , 2012
Link:
https://doi.org/10.1021/..
?
11
Structure based design, synthesis and SAR of cyclic hydroxy..:
Rueeger, Heinrich
;
Rondeau, Jean-Michel
;
McCarthy, Clive
...
Bioorganic & Medicinal Chemistry Letters. 21 (2011) 7 - p. 1942-1947 , 2011
Link:
https://doi.org/10.1016/..
?
12
Macrocyclic BACE-1 inhibitors acutely reduce Aβ in brain af..:
Lerchner, Andreas
;
Machauer, Rainer
;
Betschart, Claudia
...
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 2 - p. 603-607 , 2010
Link:
https://doi.org/10.1016/..
?
13
Signal peptide peptidase dependent cleavage of type II tran..:
Dev, Kumlesh K.
;
Chatterjee, Sandipan
;
Osinde, Maribel
...
European Journal of Pharmacology. 540 (2006) 1-3 - p. 10-17 , 2006
Link:
https://doi.org/10.1016/..
?
14
Discovery and SAR of potent, orally available and brain-pen..:
Rueeger, Heinrich
;
Gerspacher, Marc
;
Buehlmayer, Peter
...
Bioorganic & Medicinal Chemistry Letters. 14 (2004) 10 - p. 2451-2457 , 2004
Link:
https://doi.org/10.1016/..
?
15
P2-064 Rapid Aβ turnover and reduction of amyloid plaque fo..:
Abramowski, Dorothee
;
Holloway, Robert
;
Wiederhold, Karl-Heinz
...
Neurobiology of Aging. 25 (2004) - p. S242 , 2004
Link:
https://doi.org/10.1016/..
1-15