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Saiki, Anne Y.
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1

Diverse alterations associated with resistance to KRAS(G12C..:

Zhao, Yulei ; Murciano-Goroff, Yonina R. ; Xue, Jenny Y....
Nature.  599 (2021)  7886 - p. 679-683 , 2021
Link: https://doi.org/10.1038/..
 
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2

The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumou..:

Canon, Jude ; Rex, Karen ; Saiki, Anne Y....
Nature.  575 (2019)  7781 - p. 217-223 , 2019
Link: https://doi.org/10.1038/..
 
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3

Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)a..:

Shin, Youngsook ; Jeong, Joon Won ; Wurz, Ryan P....
ACS Medicinal Chemistry Letters.  10 (2019)  9 - p. 1302-1308 , 2019
Link: https://doi.org/10.1021/..
 
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4

Identifying the determinants of response to MDM2 inhibition:

Saiki, Anne Y. ; Caenepeel, Sean ; Cosgrove, Elissa...
Oncotarget.  6 (2015)  10 - p. 7701-7712 , 2015
Link: https://doi.org/10.18632..
 
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5

Discovery of Potent and Simplified Piperidinone-Based Inhib..:

Yu, Ming ; Wang, Yingcai ; Zhu, Jiang...
ACS Medicinal Chemistry Letters.  5 (2014)  8 - p. 894-899 , 2014
Link: https://doi.org/10.1021/..
 
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6

MDM2 antagonists synergize broadly and robustly with compou..:

Saiki, Anne Y. ; Caenepeel, Sean ; Yu, Dongyin...
Oncotarget.  5 (2014)  8 - p. 2030-2043 , 2014
Link: https://doi.org/10.18632..
 
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7

Discovery of AM-7209, a Potent and Selective 4-Amidobenzoic..:

Rew, Yosup ; Sun, Daqing ; Yan, Xuelei...
Journal of Medicinal Chemistry.  57 (2014)  24 - p. 10499-10511 , 2014
Link: https://doi.org/10.1021/..
 
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8

Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydr..:

Gonzalez, Ana Z. ; Li, Zhihong ; Beck, Hilary P....
Journal of Medicinal Chemistry.  57 (2014)  7 - p. 2963-2988 , 2014
Link: https://doi.org/10.1021/..
 
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9

Selective and Potent Morpholinone Inhibitors of the MDM2–p5..:

Gonzalez, Ana Z. ; Eksterowicz, John ; Bartberger, Michael D....
Journal of Medicinal Chemistry.  57 (2014)  6 - p. 2472-2488 , 2014
Link: https://doi.org/10.1021/..
 
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10

Rational Design and Binding Mode Duality of MDM2–p53 Inhibi..:

Gonzalez-Lopez de Turiso, Felix ; Sun, Daqing ; Rew, Yosup...
Journal of Medicinal Chemistry.  56 (2013)  10 - p. 4053-4070 , 2013
Link: https://doi.org/10.1021/..
 
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11

Structure-Based Design of Novel Inhibitors of the MDM2–p53 ..:

Rew, Yosup ; Sun, Daqing ; Gonzalez-Lopez De Turiso, Felix...
Journal of Medicinal Chemistry.  55 (2012)  11 - p. 4936-4954 , 2012
Link: https://doi.org/10.1021/..
 
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12

Improvement of the synthesis and pharmacokinetic properties..:

Beck, Hilary P. ; DeGraffenreid, Michael ; Fox, Brian...
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  9 - p. 2752-2755 , 2011
Link: https://doi.org/10.1016/..
 
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13

A Strategy for Discovery of Novel Broad-Spectrum Antibacter..:

Pratt, Steven D. ; David, Caroline A. ; Black-Schaefer, Candace...
SLAS Discovery.  9 (2004)  1 - p. 3-11 , 2004
Link: https://doi.org/10.1177/..
 
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14

Solution structure and function of an essential CMP kinase ..:

Yu, Liping ; Mack, Jamey ; Hajduk, Philip J....
Protein Science.  12 (2003)  11 - p. 2613-2621 , 2003
Link: https://doi.org/10.1110/..
 
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15

Scintillation Proximity Assay for Human DNA Topoisomerase I..:

Lerner, Claude G. ; Saiki, Anne Y.Chiang
Analytical Biochemistry.  240 (1996)  2 - p. 185-196 , 1996
Link: https://doi.org/10.1006/..
 
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