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Salphati, Laurent
102
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Online (102)
Mediatypes
Articles (Online) (67)
OpenAccess-fulltext (35)
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1
Early Stage Preclinical Formulation Strategies to Alter the..:
An, Le
;
De Bruyn, Tom
;
Pang, Jodie
...
Pharmaceuticals. 17 (2024) 2 - p. 179 , 2024
Link:
https://doi.org/10.3390/..
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2
Discovery and Optimization of Selective Brain-Penetrant EBP..:
Dorel, Ruth
;
Sun, Dawei
;
Carruthers, Nicholas
...
Journal of Medicinal Chemistry. 67 (2024) 6 - p. 4819-4832 , 2024
Link:
https://doi.org/10.1021/..
?
3
Absorption, metabolism, and excretion of inavolisib (GDC-00..:
Cho, Sungjoon
;
Ma, Shuguang
;
Johnson, Ryan
...
Drug Metabolism and Pharmacokinetics. 55 (2024) - p. 100922 , 2024
Link:
https://doi.org/10.1016/..
?
4
Structure-based optimization of hydroxylactam as potent, ce..:
Wei, BinQing
;
Robarge, Kirk
;
Labadie, Sharada S.
...
Bioorganic & Medicinal Chemistry Letters. 59 (2022) - p. 128576 , 2022
Link:
https://doi.org/10.1016/..
?
5
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhi..:
Hanan, Emily J.
;
Braun, Marie-Gabrielle
;
Heald, Robert A.
...
Journal of Medicinal Chemistry. 65 (2022) 24 - p. 16589-16621 , 2022
Link:
https://doi.org/10.1021/..
?
6
Growth‐rate model predicts in vivo tumor response from in v..:
Diegmiller, Rocky
;
Salphati, Laurent
;
Alicke, Bruno
...
CPT: Pharmacometrics & Systems Pharmacology. 11 (2022) 9 - p. 1183-1193 , 2022
Link:
https://doi.org/10.1002/..
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7
Discovery of Spiro-azaindoline Inhibitors of Hematopoietic ..:
Chan, Bryan K.
;
Seward, Eileen
;
Lainchbury, Michael
...
ACS Medicinal Chemistry Letters. 13 (2021) 1 - p. 84-91 , 2021
Link:
https://doi.org/10.1021/..
?
8
Structure-Based Design of Potent, Selective, and Orally Bio..:
Hu, Dennis X.
;
Patel, Snahel
;
Chen, Huifen
...
Journal of Medicinal Chemistry. , 2021
Link:
https://doi.org/10.1021/..
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9
RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives ..:
Song, Kyung W.
;
Edgar, Kyle A.
;
Hanan, Emily J.
...
Cancer Discovery. 12 (2021) 1 - p. 204-219 , 2021
Link:
https://doi.org/10.1158/..
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10
P129 - In-vivo transporter-mediated hepatic clearance of ro..:
Kumar, Vineet
;
Ishida, Kazuya
;
Salphati, Laurent
...
Drug Metabolism and Pharmacokinetics. 35 (2020) 1 - p. S61-S62 , 2020
Link:
https://doi.org/10.1016/..
?
11
Can transporter-expressing cells predict rosuvastatin uptak..:
Kumar, Vineet
;
Salphati, Laurent
;
Hop, Cornelis E.C.A.
...
Drug Metabolism and Pharmacokinetics. 34 (2019) 1 - p. S22-S23 , 2019
Link:
https://doi.org/10.1016/..
?
12
Investigation of the absolute bioavailability and human mas..:
Ma, Shuguang
;
Suchomel, Julia
;
Yanez, Evelyn
...
British Journal of Clinical Pharmacology. 85 (2019) 8 - p. 1751-1760 , 2019
Link:
https://doi.org/10.1111/..
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13
Interindividual and Regional Variability in Drug Transporte..:
Billington, Sarah
;
Salphati, Laurent
;
Hop, Cornelis E. C. A.
...
Clinical Pharmacology & Therapeutics. 106 (2019) 1 - p. 228-237 , 2019
Link:
https://doi.org/10.1002/..
?
14
Does plasma membrane and total transporter abundance differ..:
Kumar, Vineet
;
Salphati, Laurent
;
Hop, Cornelis E.C.A.
...
Drug Metabolism and Pharmacokinetics. 34 (2019) 1 - p. S17 , 2019
Link:
https://doi.org/10.1016/..
?
15
Preclinical development of the PI3K Alpha selective and PIK..:
Pang, Jodie
;
Baumgardner, Matthew
;
Braun, Marie-Gabrielle
...
Drug Metabolism and Pharmacokinetics. 34 (2019) 1 - p. S37 , 2019
Link:
https://doi.org/10.1016/..
1-15