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Scarfe, Graeme
17  results:
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1

Discovery and characterisation of quinazolines and 8-Azaqui..:

O' Donovan, Daniel H. ; Baker, David ; Ciotta, Giovanni...
Bioorganic & Medicinal Chemistry Letters.  96 (2023)  - p. 129518 , 2023
Link: https://doi.org/10.1016/..
 
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2

A Phase 1 Study to Evaluate Absolute Bioavailability and Ab..:

Miah, Kowser ; Vishwanathan, Karthick ; Scarfe, Graeme...
Clinical Pharmacology in Drug Development.  12 (2023)  4 - p. 424-435 , 2023
Link: https://doi.org/10.1002/..
 
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3

A PKPD Case Study: Achieving Clinically Relevant Exposures ..:

White, Michael J. ; Cheatham, Letitia ; Wen, Shenghua...
The AAPS Journal.  25 (2023)  4 - p. , 2023
Link: https://doi.org/10.1208/..
 
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4

Non‐Labeled, Stable Labeled, or Radiolabelled Approaches fo..:

Young, Graeme C. ; Spracklin, Douglas K. ; James, Alexander D....
Clinical Pharmacology & Therapeutics.  115 (2023)  5 - p. 931-938 , 2023
Link: https://doi.org/10.1002/..
 
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5

Considerations for Human ADME Strategy and Design Paradigm ..:

Young, Graeme C. ; Spracklin, Douglas K. ; James, Alexander D....
Clinical Pharmacology & Therapeutics.  113 (2022)  4 - p. 775-781 , 2022
Link: https://doi.org/10.1002/..
 
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6

Clinical evaluation of the potential drug–drug interactions..:

Ren, Song ; Vishwanathan, Karthick ; Cantarini, Mireille...
British Journal of Clinical Pharmacology.  88 (2021)  2 - p. 655-668 , 2021
Link: https://doi.org/10.1111/..
 
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7

Phase I study of orally administered 14Carbon-isotope label..:

MacDonald, Alexander ; Scarfe, Graeme ; Magirr, Dominic...
Cancer Chemotherapy and Pharmacology.  83 (2019)  4 - p. 787-795 , 2019
Link: https://doi.org/10.1007/..
 
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8

Physiologically Based Pharmacokinetic Modeling for Olaparib..:

Pilla Reddy, Venkatesh ; Bui, Khanh ; Scarfe, Graeme..
Clinical Pharmacology & Therapeutics.  105 (2018)  1 - p. 229-241 , 2018
Link: https://doi.org/10.1002/..
 
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9

Pharmacokinetics, absorption, and excretion of radiolabeled..:

Flach, Stephen ; Croft, Marie ; Ding, Jie...
Drug Design, Development and Therapy.  10 (2016)  - p. 3125-3132 , 2016
Link: https://doi.org/10.2147/..
 
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10

A Phase I Study to Investigate the Absorption, Pharmacokine..:

Flach, Stephen ; Scarfe, Graeme ; Dragone, Jeffrey...
Clinical Therapeutics.  38 (2016)  9 - p. 2106-2115 , 2016
Link: https://doi.org/10.1016/..
 
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11

Virtual Chromatographic Resolution Enhancement in Cryoflow ..:

Cloarec, Olivier ; Campbell, Alison ; Tseng, Li-hong...
Analytical Chemistry.  79 (2007)  9 - p. 3304-3311 , 2007
Link: https://doi.org/10.1021/..
 
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12

Improving metabolic stability and removing aldehyde oxidase..:

Degorce, Sébastien L. ; Aagaard, Anna ; Anjum, Rana...
Bioorganic & Medicinal Chemistry.  28 (2020)  23 - p. 115815 , 2020
Link: https://doi.org/10.1016/..
 
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13

High-Performance Liquid Chromatography Linked to Inductivel..:

Nicholson, Jeremy K. ; Lindon, John C. ; Scarfe, Graeme B....
Analytical Chemistry.  73 (2001)  7 - p. 1491-1494 , 2001
Link: https://doi.org/10.1021/..
 
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14

Clinical evaluation of the potential drug–drug interactions..:

Ren, Song ; Vishwanathan, Karthick ; Cantarini, Mireille...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292161/.  , 2021
Link: http://www.ncbi.nlm.nih...
 
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15

Physiologically Based Pharmacokinetic Modeling for Olaparib..:

Pilla Reddy, Venkatesh ; Bui, Khanh ; Scarfe, Graeme..
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585620/.  , 2018
Link: http://www.ncbi.nlm.nih...
 
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