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Sebhat, Iyassu K.
34  results:
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1

Molecular Profiling Reveals a Common Metabolic Signature of..:

Zhang, Ji ; Muise, Eric S. ; Han, Seongah...
Cell Reports Medicine.  1 (2020)  4 - p. 100056 , 2020
Link: https://doi.org/10.1016/..
 
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2

Hit-to-Lead Optimization and Discovery of 5-((5-([1,1′-Biph..:

Lan, Ping ; Romero, F. Anthony ; Wodka, Dariusz...
Journal of Medicinal Chemistry.  60 (2017)  21 - p. 9040-9052 , 2017
Link: https://doi.org/10.1021/..
 
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3

Systemic pan-AMPK activator MK-8722 improves glucose homeos..:

Myers, Robert W. ; Guan, Hong-Ping ; Ehrhart, Juliann...
Science.  357 (2017)  6350 - p. 507-511 , 2017
Link: https://www.jstor.org/st..
 
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4

Discovery of MK-8722: A Systemic, Direct Pan-Activator of A..:

Feng, Danqing ; Biftu, Tesfaye ; Romero, F. Anthony...
ACS Medicinal Chemistry Letters.  9 (2017)  1 - p. 39-44 , 2017
Link: https://doi.org/10.1021/..
 
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5

A new class of prolylcarboxypeptidase inhibitors, Part 1: D..:

Graham, Thomas H. ; Liu, Wensheng ; Verras, Andreas...
Bioorganic & Medicinal Chemistry Letters.  22 (2012)  8 - p. 2811-2817 , 2012
Link: https://doi.org/10.1016/..
 
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6

Discovery of a piperazine urea based compound as a potent, ..:

Hong, Qingmei ; Bakshi, Raman K. ; Palucki, Brenda L....
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  8 - p. 2330-2334 , 2011
Link: https://doi.org/10.1016/..
 
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7

Discovery of highly potent and efficacious MC4R agonists wi..:

He, Shuwen ; Ye, Zhixiong ; Dobbelaar, Peter H....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  22 - p. 6524-6532 , 2010
Link: https://doi.org/10.1016/..
 
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8

Discovery of MK-5046, a Potent, Selective Bombesin Receptor..:

Sebhat, Iyassu K. ; Franklin, Christopher ; Lo, Michael M.-C....
ACS Medicinal Chemistry Letters.  2 (2010)  1 - p. 43-47 , 2010
Link: https://doi.org/10.1021/..
 
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9

Discovery of potent, selective, and orally bioavailable 3H-..:

Guo, Liangqin ; Ye, Zhixiong ; Liu, Jian...
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  16 - p. 4895-4900 , 2010
Link: https://doi.org/10.1016/..
 
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10

Optimization of privileged structures for selective and pot..:

Hong, Qingmei ; Bakshi, Raman K. ; Dellureficio, James...
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  15 - p. 4483-4486 , 2010
Link: https://doi.org/10.1016/..
 
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11

Discovery of a spiroindane based compound as a potent, sele..:

He, Shuwen ; Ye, Zhixiong ; Dobbelaar, Peter H....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  7 - p. 2106-2110 , 2010
Link: https://doi.org/10.1016/..
 
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12

Synthesis and SAR of derivatives based on 2-biarylethylimid..:

Liu, Jian ; He, Shuwen ; Jian, Tianying...
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  7 - p. 2074-2077 , 2010
Link: https://doi.org/10.1016/..
 
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13

Synthesis and SAR of heterocyclic carboxylic acid isosteres..:

Hadden, Mark ; Goodman, Allan ; Guo, Cheng...
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  9 - p. 2912-2915 , 2010
Link: https://doi.org/10.1016/..
 
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14

Spiroindane based amides as potent and selective MC4R agoni..:

He, Shuwen ; Ye, Zhixiong ; Dobbelaar, Peter H....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  15 - p. 4399-4405 , 2010
Link: https://doi.org/10.1016/..
 
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15

Discovery of substituted biphenyl imidazoles as potent, bio..:

He, Shuwen ; Dobbelaar, Peter H. ; Liu, Jian...
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  6 - p. 1913-1917 , 2010
Link: https://doi.org/10.1016/..
 
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