E-LIB Suche - Ergebnisse für: Shaw, David E.

1

Discovery of lirafugratinib (RLY-4008), a highly selective ..:

Schönherr, Heike ; Ayaz, Pelin ; Taylor, Alexander M....
Proceedings of the National Academy of Sciences. 121 (2024) 6 - p. , 2024

Link: https://doi.org/10.1073/..

2

Times Square Sampling: An Adaptive Algorithm for Free Energ..:

Predescu, Cristian ; Snarski, Michael ; Robinson-Mosher, Avi...
Journal of Computational and Graphical Statistics. , 2024

Link: https://doi.org/10.1080/..

3

Desensitization dynamics of the AMPA receptor:

Aittoniemi, Jussi ; Jensen, Morten Ø. ; Pan, Albert C..
Structure. 31 (2023) 6 - p. 724-734.e3 , 2023

Link: https://doi.org/10.1016/..

4

Structural mechanism of a drug-binding process involving a ..:

Ayaz, Pelin ; Lyczek, Agatha ; Paung, YiTing...
Nature Communications. 14 (2023) 1 - p. , 2023

Link: https://doi.org/10.1038/..

5

Functional dynamics and allosteric modulation of TRPA1:

Koldsø, Heidi ; Jensen, Morten Ø. ; Jogini, Vishwanath.
Structure. 31 (2023) 12 - p. 1556-1566.e3 , 2023

Link: https://doi.org/10.1016/..

6

Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Des..:

Taylor, Alexander M. ; Williams, Bret R. ; Giordanetto, Fabrizio...
Journal of Medicinal Chemistry. 66 (2023) 19 - p. 13384-13399 , 2023

Link: https://doi.org/10.1021/..

7

A Conserved Local Structural Motif Controls the Kinetics of..:

Yeh, Christine Y. ; Izaguirre, Jesus A. ; Greisman, Jack B....
Journal of Chemical Information and Modeling. 63 (2023) 13 - p. 4115-4124 , 2023

Link: https://doi.org/10.1021/..

8

Discovery and Validation of the Binding Poses of Allosteric..:

Greisman, Jack B. ; Willmore, Lindsay ; Yeh, Christine Y....
Journal of Chemical Information and Modeling. 63 (2023) 9 - p. 2644-2650 , 2023

Link: https://doi.org/10.1021/..

9

RLY-4008, the First Highly Selective FGFR2 Inhibitor with A..:

Subbiah, Vivek ; Sahai, Vaibhav ; Maglic, Dejan...
Cancer Discovery. 13 (2023) 9 - p. 2012-2031 , 2023

Link: https://doi.org/10.1158/..

10

Gating and modulation of an inward-rectifier potassium chan..:

Jogini, Vishwanath ; Jensen, Morten Ø. ; Shaw, David E.
Journal of General Physiology. 155 (2022) 2 - p. , 2022

Link: https://doi.org/10.1085/..

11

Ensemble cryo-EM reveals conformational states of the nsp13..:

Chen, James ; Wang, Qi ; Malone, Brandon...
Nature Structural & Molecular Biology. 29 (2022) 3 - p. 250-260 , 2022

Link: https://doi.org/10.1038/..

12

The Specialized High-Performance Network on Anton 3:

, In: 2022 IEEE International Symposium on High-Performance Computer Architecture (HPCA),

Shim, Keun Sup ; Greskamp, Brian ; Towles, Brian... - p. 1211-1223 , 2022

Link: https://doi.org/10.1109/..

13

How does a small molecule bind at a cryptic binding site?:

Shan, Yibing ; Mysore, Venkatesh P. ; Leffler, Abba E....
PLOS Computational Biology. 18 (2022) 3 - p. e1009817 , 2022

Link: https://doi.org/10.1371/..

14

Targetable HER3 functions driving tumorigenic signaling in ..:

Campbell, Marcia R. ; Ruiz-Saenz, Ana ; Peterson, Elliott...
Cell Reports. 38 (2022) 5 - p. 110291 , 2022

Link: https://doi.org/10.1016/..

15

Development of Force Field Parameters for the Simulation of..:

Tucker, Maxwell R. ; Piana, Stefano ; Tan, Dazhi..
The Journal of Physical Chemistry B. 126 (2022) 24 - p. 4442-4457 , 2022

Link: https://doi.org/10.1021/..