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Sheffler, Douglas J.
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1

Neuroscience targets and human studies: future translationa..:

Haass-Koffler, Carolina L. ; Sheffler, Douglas J.
Neuropsychopharmacology.  48 (2023)  5 - p. 711-712 , 2023
Link: https://doi.org/10.1038/..
 
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2

Development and use of a high-throughput screen to identify..:

Haass-Koffler, Carolina L. ; Francis, T. Chase ; Gandhi, Pauravi...
SLAS Discovery.  27 (2022)  8 - p. 448-459 , 2022
Link: https://doi.org/10.1016/..
 
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3

Novel potent azetidine-based compounds irreversibly inhibit..:

Yue, Peibin ; Zhu, Yinsong ; Brotherton-Pleiss, Christine...
Cancer Letters.  534 (2022)  - p. 215613 , 2022
Link: https://doi.org/10.1016/..
 
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4

Corticotropin Releasing Factor Binding Protein as a Novel T..:

Curley, Dallece E. ; Webb, Ashley E. ; Sheffler, Douglas J..
Frontiers in Behavioral Neuroscience.  15 (2021)  - p. , 2021
Link: https://doi.org/10.3389/..
 
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5

Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/..:

Bata, Nicole ; Chaikuad, Apirat ; Bakas, Nicole A....
Journal of Medicinal Chemistry.  65 (2021)  2 - p. 1352-1369 , 2021
Link: https://doi.org/10.1021/..
 
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6

Synthesis and preliminary studies of 11C-labeled tetrahydro..:

Zhang, Xiaofei ; Zhang, Yiding ; Chen, Zhen...
Theranostics.  10 (2020)  24 - p. 11178-11196 , 2020
Link: https://doi.org/10.7150/..
 
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7

Identification and Development of a New Positron Emission T..:

Yamasaki, Tomoteru ; Zhang, Xiaofei ; Kumata, Katsushi...
Journal of Medicinal Chemistry.  63 (2020)  20 - p. 11469-11483 , 2020
Link: https://doi.org/10.1021/..
 
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8

Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosp.. 

JoVE : Cancer Research
Lambert, Lester J. ; Romero, Celeste ; Sheffler, Douglas J.... , 2020
Link: https://www.jove.com/t/6..
 
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9

Design, Synthesis, and Characterization of an Orally Active..:

Ren, Huiyu ; Bakas, Nicole A. ; Vamos, Mitchell...
Journal of Medicinal Chemistry.  63 (2020)  23 - p. 14609-14625 , 2020
Link: https://doi.org/10.1021/..
 
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10

A cellular target engagement assay for the characterization..:

Romero, Celeste ; Lambert, Lester J. ; Sheffler, Douglas J....
Journal of Biological Chemistry.  295 (2020)  9 - p. 2601-2613 , 2020
Link: https://doi.org/10.1074/..
 
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11

A combination of flow and batch mode processes for the effi..:

Dhanya, Raveendra Panickar ; Herath, Ananda ; Sheffler, Douglas J..
Tetrahedron.  74 (2018)  25 - p. 3165-3170 , 2018
Link: https://doi.org/10.1016/..
 
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12

Metabotropic Glutamate Receptor 5 as a Target for the Treat..:

Barnes, Samuel A. ; Sheffler, Douglas J. ; Semenova, Svetlana..
Biological Psychiatry.  83 (2018)  11 - p. 955-962 , 2018
Link: https://doi.org/10.1016/..
 
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13

Co-Activation of Metabotropic Glutamate Receptor 3 and Beta..:

Walker, Adam G ; Sheffler, Douglas J ; Lewis, Andrew S...
Neuropsychopharmacology.  42 (2017)  13 - p. 2553-2566 , 2017
Link: https://doi.org/10.1038/..
 
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14

Synthesis and Preliminary Studies of a Novel Negative Allos..:

Zhang, Xiaofei ; Kumata, Katsushi ; Yamasaki, Tomoteru...
ACS Chemical Neuroscience.  8 (2017)  9 - p. 1937-1948 , 2017
Link: https://doi.org/10.1021/..
 
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15

Corrigendum to "Novel GlyT1 inhibitor chemotypes by scaffol..:

Sheffler, Douglas J. ; Nedelcovych, Michael T. ; Williams, Richard...
Bioorganic & Medicinal Chemistry Letters.  27 (2017)  9 - p. 2079 , 2017
Link: https://doi.org/10.1016/..
 
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