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Shima, Fumi
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1

Oncogenic mutations Q61L and Q61H confer active form-like s..:

Matsumoto, Shigeyuki ; Taniguchi-Tamura, Haruka ; Araki, Mitsugu...
Biochemical and Biophysical Research Communications.  565 (2021)  - p. 85-90 , 2021
Link: https://doi.org/10.1016/..
 
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2

Molecular Basis for Allosteric Inhibition of GTP-Bound H-Ra..:

Matsumoto, Shigeyuki ; Hiraga, Toshiki ; Hayashi, Yuki...
Biochemistry.  57 (2018)  36 - p. 5350-5358 , 2018
Link: https://doi.org/10.1021/..
 
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3

Ras inhibitors display an anti-metastatic effect by downreg..:

Yoshikawa, Yoko ; Takano, Osamu ; Kato, Ichiro...
Cancer Letters.  410 (2017)  - p. 82-91 , 2017
Link: https://doi.org/10.1016/..
 
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4

Structural transition of solvated H-Ras/GTP revealed by mol..:

Matsunaga, Shota ; Hano, Yuta ; Saito, Yuta...
Journal of Molecular Graphics and Modelling.  77 (2017)  - p. 51-63 , 2017
Link: https://doi.org/10.1016/..
 
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5

Molecular Mechanism for Conformational Dynamics of Ras·GTP ..:

Matsumoto, Shigeyuki ; Miyano, Nao ; Baba, Seiki...
Scientific Reports.  6 (2016)  1 - p. , 2016
Link: https://doi.org/10.1038/..
 
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6

Current status of the development of Ras inhibitors:

Shima, Fumi ; Matsumoto, Shigeyuki ; Yoshikawa, Yoko...
Journal of Biochemistry.  158 (2015)  2 - p. 91-99 , 2015
Link: https://doi.org/10.1093/..
 
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7

In silicodiscovery of small-molecule Ras inhibitors that di..:

Shima, Fumi ; Yoshikawa, Yoko ; Ye, Min...
Proceedings of the National Academy of Sciences.  110 (2013)  20 - p. 8182-8187 , 2013
Link: https://doi.org/10.1073/..
 
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8

In silico discovery of small-molecule Ras inhibitors that d..:

Shima, Fumi ; Yoshikawa, Yoko ; Ye, Min...
Proceedings of the National Academy of Sciences of the United States of America.  110 (2013)  20 - p. 8182-8187 , 2013
Link: https://www.jstor.org/st..
 
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9

Crystal structures of the state 1 conformations of the GTP‐..:

Muraoka, Shin ; Shima, Fumi ; Araki, Mitsugu...
FEBS Letters.  586 (2012)  12 - p. 1715-1718 , 2012
Link: https://doi.org/10.1016/..
 
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10

Critical Roles of Interactions among Switch I-preceding Res..:

Matsumoto, Kousuke ; Shima, Fumi ; Muraoka, Shin...
Journal of Biological Chemistry.  286 (2011)  17 - p. 15403-15412 , 2011
Link: https://doi.org/10.1074/..
 
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11

Solution Structure of the State 1 Conformer of GTP-bound H-..:

Araki, Mitsugu ; Shima, Fumi ; Yoshikawa, Yoko...
Journal of Biological Chemistry.  286 (2011)  45 - p. 39644-39653 , 2011
Link: https://doi.org/10.1074/..
 
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12

Structural Basis for Conformational Dynamics of GTP-bound R..:

Shima, Fumi ; Ijiri, Yuichi ; Muraoka, Shin...
Journal of Biological Chemistry.  285 (2010)  29 - p. 22696-22705 , 2010
Link: https://doi.org/10.1074/..
 
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13

Biochemical characterization of missense mutations in the A..:

Kobayashi, Tetsuo ; Hori, Yuji ; Ueda, Nami...
Biochemical and Biophysical Research Communications.  381 (2009)  3 - p. 439-442 , 2009
Link: https://doi.org/10.1016/..
 
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14

Two conformational states of Ras GTPase exhibit differentia..:

Liao, Jingling ; Shima, Fumi ; Araki, Mitsugu...
Biochemical and Biophysical Research Communications.  369 (2008)  2 - p. 327-332 , 2008
Link: https://doi.org/10.1016/..
 
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15

Crystal Structure of M-Ras Reveals a GTP-bound "Off" State ..:

Ye, Min ; Shima, Fumi ; Muraoka, Shin...
Journal of Biological Chemistry.  280 (2005)  35 - p. 31267-31275 , 2005
Link: https://doi.org/10.1074/..
 
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