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Sloop, Kyle W.
141  results:
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1

Effect of Food Consumption on the Pharmacokinetics, Safety,..:

Ma, Xiaosu ; Liu, Rong ; Pratt, Edward J....
Diabetes Therapy.  15 (2024)  4 - p. 819-832 , 2024
Link: https://doi.org/10.1007/..
 
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2

The incretin co-agonist tirzepatide requires GIPR for hormo..:

El, Kimberley ; Douros, Jonathan D. ; Willard, Francis S....
Nature Metabolism.  5 (2023)  6 - p. 945-954 , 2023
Link: https://doi.org/10.1038/..
 
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3

Orforglipron (LY3502970), a novel, oral non‐peptide glucago..:

Pratt, Edward ; Ma, Xiaosu ; Liu, Rong...
Diabetes, Obesity and Metabolism.  25 (2023)  9 - p. 2634-2641 , 2023
Link: https://doi.org/10.1111/..
 
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4

Orforglipron (LY3502970), a novel, oral non‐peptide glucago..:

Pratt, Edward ; Ma, Xiaosu ; Liu, Rong...
Diabetes, Obesity and Metabolism.  25 (2023)  9 - p. 2642-2649 , 2023
Link: https://doi.org/10.1111/..
 
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5

LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor..:

Coskun, Tamer ; Urva, Shweta ; Roell, William C....
Cell Metabolism.  34 (2022)  9 - p. 1234-1247.e9 , 2022
Link: https://doi.org/10.1016/..
 
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6

Is Glucagon Receptor Activation the Thermogenic Solution fo..:

Conceição-Furber, Ellen ; Coskun, Tamer ; Sloop, Kyle W..
Frontiers in Endocrinology.  13 (2022)  - p. , 2022
Link: https://doi.org/10.3389/..
 
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7

Tirzepatide induces a thermogenic-like amino acid signature..:

Samms, Ricardo J. ; Zhang, GuoFang ; He, Wentao...
Molecular Metabolism.  64 (2022)  - p. 101550 , 2022
Link: https://doi.org/10.1016/..
 
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8

Structural determinants of dual incretin receptor agonism b..:

Sun, Bingfa ; Willard, Francis S. ; Feng, Dan...
Proceedings of the National Academy of Sciences.  119 (2022)  13 - p. , 2022
Link: https://doi.org/10.1073/..
 
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9

Glucagon blockade restores functional β-cell mass in type 1..:

Wang, May-Yun ; Dean, E. Danielle ; Quittner-Strom, Ezekiel...
Proceedings of the National Academy of Sciences.  118 (2021)  9 - p. , 2021
Link: https://doi.org/10.1073/..
 
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10

Discovery of an Orally Efficacious Positive Allosteric Modu..:

Willard, Francis S. ; Wainscott, David B. ; Showalter, Aaron D....
Journal of Medicinal Chemistry.  64 (2021)  6 - p. 3439-3448 , 2021
Link: https://doi.org/10.1021/..
 
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11

GLP-1 receptor signaling increases PCSK1 and β cell feature..:

Saikia, Mridusmita ; Holter, Marlena M. ; Donahue, Leanne R....
JCI Insight.  6 (2021)  3 - p. , 2021
Link: https://doi.org/10.1172/..
 
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12

How May GIP Enhance the Therapeutic Efficacy of GLP-1?:

Samms, Ricardo J. ; Coghlan, Matthew P. ; Sloop, Kyle W.
Trends in Endocrinology & Metabolism.  31 (2020)  6 - p. 410-421 , 2020
Link: https://doi.org/10.1016/..
 
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13

Synthetic protease-activated class B GPCRs:

Willard, Francis S. ; Meredith, Tamika D. ; Showalter, Aaron D....
Biochemical and Biophysical Research Communications.  530 (2020)  1 - p. 246-251 , 2020
Link: https://doi.org/10.1016/..
 
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14

Tirzepatide is an imbalanced and biased dual GIP and GLP-1 ..:

Willard, Francis S. ; Douros, Jonathan D. ; Gabe, Maria B.N....
JCI Insight.  5 (2020)  17 - p. , 2020
Link: https://doi.org/10.1172/..
 
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15

Structural basis for GLP-1 receptor activation by LY3502970..:

Kawai, Takahiro ; Sun, Bingfa ; Yoshino, Hitoshi...
Proceedings of the National Academy of Sciences of the United States of America.  117 (2020)  47 - p. 29959-29967 , 2020
Link: https://www.jstor.org/st..
 
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