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Sousa, Jacquelyn
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1

Quantifying the activity profile of ASO and siRNA conjugate..:

Sarli, Samantha L ; Fakih, Hassan H ; Kelly, Karen...
Nucleic Acids Research.  52 (2024)  9 - p. 4799-4817 , 2024
Link: https://doi.org/10.1093/..
 
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2

THU-198 In vitro and in vivo pharmacological characterizati..:

Song, Jieun ; Deval, Jerome ; Adame, Lillian...
Journal of Hepatology.  80 (2024)  - p. S564-S565 , 2024
Link: https://doi.org/10.1016/..
 
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3

TOP-357 Second generation HBV siRNAs with novel chemistries..:

Hong, Jin ; Rajwanshi, Vivek ; Montero, Saul...
Journal of Hepatology.  80 (2024)  - p. S727-S728 , 2024
Link: https://doi.org/10.1016/..
 
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4

A combinatorial approach for achieving CNS-selective RNAi:

Ferguson, Chantal M ; Godinho, Bruno M D C ; Echeverria, Dimas...
Nucleic Acids Research.  52 (2024)  9 - p. 5273-5284 , 2024
Link: https://doi.org/10.1093/..
 
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5

Silencing Apoe with divalent‐siRNAs improves amyloid burden..:

Ferguson, Chantal M. ; Hildebrand, Samuel ; Godinho, Bruno M. D. C....
Alzheimer's & Dementia.  20 (2024)  4 - p. 2632-2652 , 2024
Link: https://doi.org/10.1002/..
 
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6

Divalent siRNAs are bioavailable in the lung and efficientl..:

Hariharan, Vignesh N. ; Shin, Minwook ; Chang, Ching-Wen...
Proceedings of the National Academy of Sciences.  120 (2023)  11 - p. , 2023
Link: https://doi.org/10.1073/..
 
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7

Rational design of a JAK1-selective siRNA inhibitor for the..:

Tang, Qi ; Fakih, Hassan H. ; Zain UI Abideen, Mohammad...
Nature Communications.  14 (2023)  1 - p. , 2023
Link: https://doi.org/10.1038/..
 
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8

G-rich motifs within phosphorothioate-based antisense oligo..:

Wang, Feng ; Calvo-Roitberg, Ezequiel ; Rembetsy-Brown, Julia M...
Nucleic Acids Research.  50 (2022)  22 - p. 12657-12673 , 2022
Link: https://doi.org/10.1093/..
 
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9

RNAi-based modulation of IFN-γ signaling in skin:

Tang, Qi ; Sousa, Jacquelyn ; Echeverria, Dimas...
Molecular Therapy.  30 (2022)  8 - p. 2709-2721 , 2022
Link: https://doi.org/10.1016/..
 
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10

Intratracheally administered LNA gapmer antisense oligonucl..:

Shin, Minwook ; Chan, Io Long ; Cao, Yuming...
Nucleic Acids Research.  50 (2022)  15 - p. 8418-8430 , 2022
Link: https://doi.org/10.1093/..
 
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11

An RNAi therapeutic targeting hepatic DGAT2 in a geneticall..:

Yenilmez, Batuhan ; Wetoska, Nicole ; Kelly, Mark...
Molecular Therapy.  30 (2022)  3 - p. 1329-1342 , 2022
Link: https://doi.org/10.1016/..
 
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12

Chemical optimization of siRNA for safe and efficient silen..:

Davis, Sarah M. ; Hariharan, Vignesh N. ; Lo, Agnes...
Molecular Therapy - Nucleic Acids.  29 (2022)  - p. 135-149 , 2022
Link: https://doi.org/10.1016/..
 
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13

The chemical structure and phosphorothioate content of hydr..:

Biscans, Annabelle ; Caiazzi, Jillian ; Davis, Sarah...
Nucleic Acids Research.  48 (2020)  14 - p. 7665-7680 , 2020
Link: https://doi.org/10.1093/..
 
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14

Single-Stranded Phosphorothioated Regions Enhance Cellular ..:

Ly, Socheata ; Echeverria, Dimas ; Sousa, Jacquelyn.
Molecular Therapy - Nucleic Acids.  21 (2020)  - p. 991-1005 , 2020
Link: https://doi.org/10.1016/..
 
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15

2′-O-Methyl at 20-mer Guide Strand 3′ Termini May Negativel..:

Davis, Sarah M. ; Sousa, Jacquelyn ; Vangjeli, Lorenc...
Molecular Therapy - Nucleic Acids.  21 (2020)  - p. 266-277 , 2020
Link: https://doi.org/10.1016/..
 
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