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Staben, Steven T.
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1

Ternary complex dissociation kinetics contribute to mutant-..:

Rosenberg, Scott C. ; Shanahan, Frances ; Yamazoe, Sayumi...
Cell Chemical Biology.  30 (2023)  2 - p. 175-187.e15 , 2023
Link: https://doi.org/10.1016/..
 
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2

Filling a nick in NIK: Extending the half-life of a NIK inh..:

Crawford, James J. ; Feng, Jianwen ; Brightbill, Hans D....
Bioorganic & Medicinal Chemistry Letters.  89 (2023)  - p. 129277 , 2023
Link: https://doi.org/10.1016/..
 
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3

A Multifaceted Hit-Finding Approach Reveals Novel LC3 Famil..:

Steffek, Micah ; Helgason, Elizabeth ; Popovych, Nataliya...
Biochemistry.  62 (2022)  3 - p. 633-644 , 2022
Link: https://doi.org/10.1021/..
 
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4

Overcoming Preclinical Safety Obstacles to Discover (S)-N-(..:

McBride, Christopher ; Trzoss, Lynnie ; Povero, Davide...
Journal of Medicinal Chemistry.  65 (2022)  21 - p. 14721-14739 , 2022
Link: https://doi.org/10.1021/..
 
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5

Targeted degradation via direct 26S proteasome recruitment:

Bashore, Charlene ; Prakash, Sumit ; Johnson, Matthew C....
Nature Chemical Biology.  19 (2022)  1 - p. 55-63 , 2022
Link: https://doi.org/10.1038/..
 
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6

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part..:

Dragovich, Peter S. ; Pillow, Thomas H. ; Blake, Robert A....
Journal of Medicinal Chemistry.  64 (2021)  5 - p. 2534-2575 , 2021
Link: https://doi.org/10.1021/..
 
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7

Selective activation of PFKL suppresses the phagocytic oxid..:

Amara, Neri ; Cooper, Madison P. ; Voronkova, Maria A....
Cell.  184 (2021)  17 - p. 4480-4494.e15 , 2021
Link: https://doi.org/10.1016/..
 
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8

RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives ..:

Song, Kyung W. ; Edgar, Kyle A. ; Hanan, Emily J....
Cancer Discovery.  12 (2021)  1 - p. 204-219 , 2021
Link: https://doi.org/10.1158/..
 
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9

Structure-Based Design of Potent, Selective, and Orally Bio..:

Hu, Dennis X. ; Patel, Snahel ; Chen, Huifen...
Journal of Medicinal Chemistry.  , 2021
Link: https://doi.org/10.1021/..
 
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10

Identifying transcriptional programs underlying cancer drug..:

Chang, Matthew T. ; Shanahan, Frances ; Nguyen, Thi Thu Thao...
Nature Biotechnology.  40 (2021)  1 - p. 86-93 , 2021
Link: https://doi.org/10.1038/..
 
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11

Primary Amine Tethered Small Molecules Promote the Degradat..:

den Besten, Willem ; Verma, Kshitij ; Yamazoe, Sayumi...
Journal of the American Chemical Society.  143 (2021)  28 - p. 10571-10575 , 2021
Link: https://doi.org/10.1021/..
 
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12

Medicinal Chemistry of Inhibiting RING-Type E3 Ubiquitin Li..:

Blaquiere, Nicole ; Villemure, Elisia ; Staben, Steven T.
Journal of Medicinal Chemistry.  63 (2020)  15 - p. 7957-7985 , 2020
Link: https://doi.org/10.1021/..
 
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13

Monomeric Targeted Protein Degraders:

Hanan, Emily J. ; Liang, Jun ; Wang, Xiaojing...
Journal of Medicinal Chemistry.  63 (2020)  20 - p. 11330-11361 , 2020
Link: https://doi.org/10.1021/..
 
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14

Structure Based Design of Potent Selective Inhibitors of Pr..:

Feng, Jianwen A. ; Lee, Patrick ; Alaoui, Moulay Hicham...
ACS Medicinal Chemistry Letters.  10 (2019)  9 - p. 1260-1265 , 2019
Link: https://doi.org/10.1021/..
 
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15

Correction: MCC950/CRID3 potently targets the NACHT domain ..:

Walle, Lieselotte Vande ; Stowe, Irma B. ; Šácha, Pavel...
PLOS Biology.  17 (2019)  10 - p. e3000529 , 2019
Link: https://doi.org/10.1371/..
 
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