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Stammers, Timothy A.
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1

Aza follow-ups to BI 207524, a thumb pocket 1 HCV NS5B poly..:

Beaulieu, Pierre L. ; Bolger, Gordon ; Duplessis, Martin...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  5 - p. 1135-1139 , 2015
Link: https://doi.org/10.1016/..
 
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2

Multi-parameter optimization of aza-follow-ups to BI 207524..:

Beaulieu, Pierre L. ; Bolger, Gordon ; Deon, Dan...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  5 - p. 1140-1145 , 2015
Link: https://doi.org/10.1016/..
 
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3

A prodrug strategy for the oral delivery of a poorly solubl..:

Beaulieu, Pierre L. ; De Marte, Josie ; Garneau, Michel...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  2 - p. 210-215 , 2015
Link: https://doi.org/10.1016/..
 
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4

Discovery of BI 207524, an Indole Diamide NS5B Thumb Pocket..:

Beaulieu, Pierre L. ; Anderson, Paul C. ; Bethell, Richard...
Journal of Medicinal Chemistry.  57 (2014)  23 - p. 10130-10143 , 2014
Link: https://doi.org/10.1021/..
 
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5

Discovery of a novel series of non-nucleoside thumb pocket ..:

Stammers, Timothy A. ; Coulombe, René ; Rancourt, Jean...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  9 - p. 2585-2589 , 2013
Link: https://doi.org/10.1016/..
 
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6

Molecular Dynamics Simulations and Structure-Based Rational..:

Hucke, Oliver ; Coulombe, René ; Bonneau, Pierre...
Journal of Medicinal Chemistry.  57 (2013)  5 - p. 1932-1943 , 2013
Link: https://doi.org/10.1021/..
 
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7

Structure-based design of novel HCV NS5B thumb pocket 2 all..:

Beaulieu, Pierre L. ; Coulombe, René ; Duan, Jianmin...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  14 - p. 4132-4140 , 2013
Link: https://doi.org/10.1016/..
 
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8

Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase i..:

Stammers, Timothy A. ; Coulombe, René ; Duplessis, Martin...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  24 - p. 6879-6885 , 2013
Link: https://doi.org/10.1016/..
 
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9

Conformation-Based Restrictions and Scaffold Replacements i..:

LaPlante, Steven R. ; Bös, Michael ; Brochu, Christian...
Journal of Medicinal Chemistry.  57 (2013)  5 - p. 1845-1854 , 2013
Link: https://doi.org/10.1021/..
 
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10

Enantiomeric Atropisomers Inhibit HCV Polymerase and/or HIV..:

LaPlante, Steven R. ; Forgione, Pat ; Boucher, Colette...
Journal of Medicinal Chemistry.  57 (2013)  5 - p. 1944-1951 , 2013
Link: https://doi.org/10.1021/..
 
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11

Indole 5-carboxamide Thumb Pocket I inhibitors of HCV NS5B ..:

Beaulieu, Pierre L. ; Chabot, Catherine ; Duan, Jianmin...
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  12 - p. 3664-3670 , 2011
Link: https://doi.org/10.1016/..
 
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12

N-Acetamideindolecarboxylic acid allosteric 'finger-loop' i..:

Beaulieu, Pierre L. ; Jolicoeur, Eric ; Gillard, James...
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  3 - p. 857-861 , 2010
Link: https://doi.org/10.1016/..
 
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13

Improved replicon cellular activity of non-nucleoside allos..:

Beaulieu, Pierre L. ; Gillard, James ; Bykowski, Darren...
Bioorganic & Medicinal Chemistry Letters.  16 (2006)  19 - p. 4987-4993 , 2006
Link: https://doi.org/10.1016/..
 
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14

Oxabicyclo[3.2.1]oct-6-enes as Templates for the Stereosele..:

Lautens, Mark ; Stammers, Timothy
Synthesis.  2002 (2002)  14 Special Issue - p. , 2002
Link: https://doi.org/10.1055/..
 
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15

Cerium(III) chloride promoted opening of [3.2.1] oxabicycle..:

Lautens, Mark ; de Frutos, Oscar ; Stammers, Timothy A.
Tetrahedron Letters.  40 (1999)  48 - p. 8317-8321 , 1999
Link: https://doi.org/10.1016/..
 
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