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Takafumi, Takai
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1

Approach to de-risk structural alerts in compound progressi..:

Rotter, Charles ; Estrella, Heather ; Takafumi, Takai.
Drug Metabolism and Pharmacokinetics.  55 (2024)  - p. 100939 , 2024
Link: https://doi.org/10.1016/..
 
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2

Retrospective Analysis of Chemical Structure-Based in silic..:

Takai, Takafumi ; Jeffy, Brandon D ; Prabhu, Swathi.
Computational Toxicology.  26 (2023)  - p. 100273 , 2023
Link: https://doi.org/10.1016/..
 
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3

Discovery of a Potent and Orally Bioavailable Melatonin Rec..:

Hoashi, Yasutaka ; Takai, Takafumi ; Kosugi, Yohei...
Journal of Medicinal Chemistry.  64 (2021)  6 - p. 3059-3074 , 2021
Link: https://doi.org/10.1021/..
 
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4

Structure-based design, synthesis, and biological evaluatio..:

Kaieda, Akira ; Takahashi, Masashi ; Takai, Takafumi...
Bioorganic & Medicinal Chemistry.  26 (2018)  3 - p. 647-660 , 2018
Link: https://doi.org/10.1016/..
 
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5

Discovery of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole..:

Kojima, Takuto ; Mochizuki, Michiyo ; Takai, Takafumi...
Bioorganic & Medicinal Chemistry.  26 (2018)  9 - p. 2229-2250 , 2018
Link: https://doi.org/10.1016/..
 
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6

Practical application of 3-substituted-2,6-difluoropyridine..:

Katoh, Taisuke ; Tomata, Yoshihide ; Setoh, Masaki...
Bioorganic & Medicinal Chemistry Letters.  27 (2017)  11 - p. 2497-2501 , 2017
Link: https://doi.org/10.1016/..
 
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7

Discovery of a novel B-cell lymphoma 6 (BCL6)–corepressor i..:

Yasui, Takeshi ; Yamamoto, Takeshi ; Sakai, Nozomu...
Bioorganic & Medicinal Chemistry.  25 (2017)  17 - p. 4876-4886 , 2017
Link: https://doi.org/10.1016/..
 
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8

Discovery of novel 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]..:

Takai, Takafumi ; Koike, Tatsuki ; Nakamura, Minoru...
Bioorganic & Medicinal Chemistry.  24 (2016)  14 - p. 3192-3206 , 2016
Link: https://doi.org/10.1016/..
 
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9

Discovery and optimization of 1,7-disubstituted-2,2-dimethy..:

Katoh, Taisuke ; Takai, Takafumi ; Yukawa, Takafumi...
Bioorganic & Medicinal Chemistry.  24 (2016)  11 - p. 2466-2475 , 2016
Link: https://doi.org/10.1016/..
 
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10

Design and synthesis of piperazine derivatives as a novel c..:

Takai, Takafumi ; Koike, Tatsuki ; Honda, Eiji...
Bioorganic & Medicinal Chemistry.  23 (2015)  9 - p. 1923-1934 , 2015
Link: https://doi.org/10.1016/..
 
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11

Discovery of novel 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]..:

Takai, Takafumi ; Hoashi, Yasutaka ; Tomata, Yoshihide...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  19 - p. 4245-4249 , 2015
Link: https://doi.org/10.1016/..
 
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12

Discovery of a Novel Series of N-Phenylindoline-5-sulfonami..:

Sato, Kenjiro ; Takahagi, Hiroki ; Yoshikawa, Takeshi...
Journal of Medicinal Chemistry.  58 (2015)  9 - p. 3892-3909 , 2015
Link: https://doi.org/10.1021/..
 
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13

Synthesis of a novel tricyclic 1,6,7,8-tetrahydro-2H-cyclop..:

Hoashi, Yasutaka ; Takai, Takafumi ; Koike, Tatsuki.
Tetrahedron Letters.  55 (2014)  29 - p. 4014-4016 , 2014
Link: https://doi.org/10.1016/..
 
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14

Synthesis of pyrazolo[1,5-a]pyridines by thermal intramolec..:

Hoashi, Yasutaka ; Takai, Takafumi ; Kotani, Etsuo.
Tetrahedron Letters.  54 (2013)  17 - p. 2199-2202 , 2013
Link: https://doi.org/10.1016/..
 
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15

Synthesis of 4-aza analog of ramelteon: a novel tricyclic 1..:

Koike, Tatsuki ; Hoashi, Yasutaka ; Takai, Takafumi.
Tetrahedron Letters.  52 (2011)  23 - p. 3009-3011 , 2011
Link: https://doi.org/10.1016/..
 
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