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Tohyama, Kimio
33  results:
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1

Discovery of a novel series of medium-sized cyclic enterope..:

Kikuchi, Fumiaki ; Ikeda, Zenichi ; Kakegawa, Keiko...
Bioorganic & Medicinal Chemistry.  93 (2023)  - p. 117462 , 2023
Link: https://doi.org/10.1016/..
 
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2

Discovery of a Novel Series of Potent, Selective, Orally Av..:

Ikeda, Zenichi ; Kamei, Taku ; Sasaki, Yusuke...
Journal of Medicinal Chemistry.  66 (2023)  9 - p. 6354-6371 , 2023
Link: https://doi.org/10.1021/..
 
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3

Novel insights in drug transporter sciences: the year 2021 ..:

Chothe, Paresh P. ; Mitra, Pallabi ; Nakakariya, Masanori...
Drug Metabolism Reviews.  54 (2022)  3 - p. 299-317 , 2022
Link: https://doi.org/10.1080/..
 
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4

Design, Synthesis, and Biological Evaluation of a Novel Ser..:

Ikeda, Zenichi ; Kakegawa, Keiko ; Kikuchi, Fumiaki...
Journal of Medicinal Chemistry.  65 (2022)  12 - p. 8456-8477 , 2022
Link: https://doi.org/10.1021/..
 
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5

Protective effect of a novel phosphodiesterase 4 selective ..:

Ookawara, Mitsugi ; Nio, Yasunori ; Yamasaki, Midori...
European Journal of Pharmacology.  894 (2021)  - p. 173852 , 2021
Link: https://doi.org/10.1016/..
 
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6

Translational CNS Steady-State Drug Disposition Model in Ra..:

Sato, Sho ; Matsumiya, Kota ; Tohyama, Kimio.
The AAPS Journal.  23 (2021)  4 - p. , 2021
Link: https://doi.org/10.1208/..
 
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7

Ameliorative effect of phosphodiesterase 4 and 5 inhibitors..:

Nio, Yasunori ; Ookawara, Mitsugi ; Yamasaki, Midori...
The FASEB Journal.  34 (2020)  11 - p. 14997-15014 , 2020
Link: https://doi.org/10.1096/..
 
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8

Investigation of MDR1-overexpressing cell lines to derive a..:

Sato, Sho ; Tohyama, Kimio ; Kosugi, Yohei
European Journal of Pharmaceutical Sciences.  142 (2020)  - p. 105119 , 2020
Link: https://doi.org/10.1016/..
 
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9

SAT-356-Anti-metabolic, anti-inflammatory and anti-fibrotic..:

Amano, Yuichiro ; Tsuchiya, Shuntarou ; Matsumoto, Mitsuharu...
Journal of Hepatology.  70 (2019)  1 - p. e796 , 2019
Link: https://doi.org/10.1016/..
 
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10

Relationship of MATE1 Inhibition and Cytotoxicity in Nephro..:

Tohyama, Kimio ; Chisaki, Ikumi ; Takai, Yuichi...
Toxicological Sciences.  170 (2019)  1 - p. 223-233 , 2019
Link: https://doi.org/10.1093/..
 
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11

Discovery and characterization of a small‐molecule enterope..:

Sasaki, Masako ; Miyahisa, Ikuo ; Itono, Sachiko...
Pharmacology Research & Perspectives.  7 (2019)  5 - p. , 2019
Link: https://doi.org/10.1002/..
 
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12

Direct Drug Delivery of Low-Permeable Compounds to the Cent..:

Iwasaki, Shinji ; Yamamoto, Syunsuke ; Sano, Noriyasu...
Pharmaceutical Research.  36 (2019)  5 - p. , 2019
Link: https://doi.org/10.1007/..
 
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13

Combination effects of alogliptin and pioglitazone on steat..:

Amano, Yuichiro ; Tsuchiya, Shuntarou ; Imai, Mayumi...
Biochemical and Biophysical Research Communications.  497 (2018)  1 - p. 207-213 , 2018
Link: https://doi.org/10.1016/..
 
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14

Phosphodiesterase 4 inhibition reduces lung fibrosis follow..:

Sisson, Thomas H. ; Christensen, Paul J. ; Muraki, Yo...
Physiological Reports.  6 (2018)  12 - p. e13753 , 2018
Link: https://doi.org/10.14814..
 
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15

Time-dependent inhibition of drug transporters:

Yucha, Robert ; Chuang, Bei-Ching ; Fukushi, Chiharu...
Drug Metabolism and Pharmacokinetics.  33 (2018)  1 - p. S92-S93 , 2018
Link: https://doi.org/10.1016/..
 
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